Record Information
Version1.0
Created at2020-04-17 18:45:04 UTC
Updated at2020-11-18 16:38:53 UTC
CannabisDB IDCDB004868
Secondary Accession NumbersNot Available
Cannabis Compound Identification
Common NameNAD
DescriptionNAD+, also known as codehydrogenase I or coenzyme I, belongs to the class of organic compounds known as (5'->5')-dinucleotides. These are dinucleotides where the two bases are connected via a (5'->5')-phosphodiester linkage. NAD+ is a very strong basic compound (based on its pKa). In humans, NAD+ is involved in citric acid cycle. Outside of the human body, NAD+ has been detected, but not quantified in, several different foods, such as garden tomato, devilfish, saffrons, cloud ear fungus, and bog bilberries. This could make NAD+ a potential biomarker for the consumption of these foods. NAD is expected to be in Cannabis as all living plants are known to produce and metabolize it.
Structure
Thumb
Synonyms
ValueSource
Codehydrogenase IChEBI
Coenzyme IChEBI
Cozymase IChEBI
Diphosphopyridine nucleotideChEBI
DPNChEBI
NadideChEBI
NICOTINAMIDE-adenine-dinucleotideChEBI
Adenine dinucleotide, dihydronicotinamideMeSH
NADMeSH
Nicotinamide-adenine dinucleotideMeSH
Nucleotide, diphosphopyridineMeSH
Dihydronicotinamide adenine dinucleotideMeSH
NADHMeSH
Nicotinamide adenine dinucleotideMeSH
Dinucleotide, nicotinamide-adenineMeSH
Dinucleotide, dihydronicotinamide adenineMeSH
Adenine-nicotinamide dinucleotideHMDB
NAD+HMDB
Oxidized diphosphopyridine nucleotideHMDB
beta-Diphosphopyridine nucleotideHMDB
beta-NADHMDB
beta-NAD+HMDB
beta-Nicotinamide adenine dinucleotideHMDB
beta-Nicotinamide adenine dinucleotide hydrateHMDB
β-Diphosphopyridine nucleotideHMDB
β-NADHMDB
β-NAD+HMDB
β-Nicotinamide adenine dinucleotideHMDB
β-Nicotinamide adenine dinucleotide hydrateHMDB
Chemical FormulaC21H27N7O14P2
Average Molecular Weight663.43
Monoisotopic Molecular Weight663.1091
IUPAC Name1-[(2R,3R,4S,5R)-5-({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono}oxy)(hydroxy)phosphoryl]oxy}methyl)-3,4-dihydroxyoxolan-2-yl]-3-(C-hydroxycarbonimidoyl)-1lambda5-pyridin-1-ylium
Traditional Name1-[(2R,3R,4S,5R)-5-{[({[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono}oxy(hydroxy)phosphoryl)oxy]methyl}-3,4-dihydroxyoxolan-2-yl]-3-(C-hydroxycarbonimidoyl)-1lambda5-pyridin-1-ylium
CAS Registry Number53-84-9
SMILES
NC(=O)C1=C[N+](=CC=C1)[C@@H]1O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C2N=CN=C3N)[C@@H](O)[C@H]1O
InChI Identifier
InChI=1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
InChI KeyBAWFJGJZGIEFAR-NNYOXOHSSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as (5'->5')-dinucleotides. These are dinucleotides where the two bases are connected via a (5'->5')-phosphodiester linkage.
KingdomOrganic compounds
Super ClassNucleosides, nucleotides, and analogues
Class(5'->5')-dinucleotides
Sub ClassNot Available
Direct Parent(5'->5')-dinucleotides
Alternative Parents
Substituents
  • (5'->5')-dinucleotide
  • Purine nucleotide sugar
  • Purine ribonucleoside diphosphate
  • Purine ribonucleoside monophosphate
  • Nicotinamide-nucleotide
  • Pyridine nucleotide
  • Pentose-5-phosphate
  • Pentose phosphate
  • Glycosyl compound
  • N-glycosyl compound
  • 6-aminopurine
  • Monosaccharide phosphate
  • Organic pyrophosphate
  • Purine
  • Imidazopyrimidine
  • Nicotinamide
  • Monoalkyl phosphate
  • Aminopyrimidine
  • Monosaccharide
  • N-substituted imidazole
  • Organic phosphoric acid derivative
  • Imidolactam
  • Phosphoric acid ester
  • Alkyl phosphate
  • Pyrimidine
  • Pyridinium
  • Pyridine
  • Tetrahydrofuran
  • Azole
  • Imidazole
  • Heteroaromatic compound
  • Secondary alcohol
  • Carboximidic acid derivative
  • Carboximidic acid
  • Organoheterocyclic compound
  • Oxacycle
  • Azacycle
  • Hydrocarbon derivative
  • Organopnictogen compound
  • Organic oxide
  • Organic zwitterion
  • Primary amine
  • Organonitrogen compound
  • Amine
  • Organic nitrogen compound
  • Alcohol
  • Organic oxygen compound
  • Organooxygen compound
  • Aromatic heteropolycyclic compound
Molecular FrameworkAromatic heteropolycyclic compounds
External Descriptors
Ontology
Physiological effect

Health effect:

Disposition

Source:

Biological location:

Physical Properties
StateSolid
Experimental Properties
PropertyValueReference
Melting Point140.0 - 142.0 °CNot Available
Boiling PointNot AvailableNot Available
Water Solubility752.5 mg/mLNot Available
logPNot AvailableNot Available
Predicted Properties
PropertyValueSource
logP-1.2ALOGPS
logP-10ChemAxon
logS-2.5ALOGPS
pKa (Strongest Acidic)1.85ChemAxon
pKa (Strongest Basic)6.38ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count16ChemAxon
Hydrogen Donor Count8ChemAxon
Polar Surface Area322.08 ŲChemAxon
Rotatable Bond Count11ChemAxon
Refractivity151.81 m³·mol⁻¹ChemAxon
Polarizability58.5 ųChemAxon
Number of Rings5ChemAxon
BioavailabilityNoChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleYesChemAxon
Spectra
EI-MS/GC-MSNot Available
MS/MS
TypeDescriptionSplash KeyView
MS/MSLC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)splash10-03di-0000029000-870aa620464a4fedbe8dSpectrum
MS/MSLC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)splash10-002r-0930610000-ccd233f26036136ba3e8Spectrum
MS/MSLC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)splash10-000i-0900000000-ec77ba41ae7dbcfd08a2Spectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positivesplash10-00dl-0219003700-2f52e3c5db41066a112cSpectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positivesplash10-0uk9-0301009000-a3d0c464e56f6e320c80Spectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positivesplash10-00dl-0000090000-c18a7719161c63a71938Spectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positivesplash10-0udi-0000009000-1dde5b221786fe375304Spectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positivesplash10-0002-0911001000-bd16ca8021ab63e9e290Spectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positivesplash10-001i-0900000000-662adda5a00fce5c5017Spectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positivesplash10-03di-0900000000-a2724dbab2ca6eb7e8daSpectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Positivesplash10-00dl-0400090000-19bb49ef6fe960f224d2Spectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negativesplash10-006x-0011297400-efee4fe3a4cf024c960aSpectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negativesplash10-004i-0028900000-8ec9bcaf25513495b979Spectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negativesplash10-0a4i-0011953000-577487fb6aff29c77330Spectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negativesplash10-00di-0000009000-e1d0afb4e7926a0f845eSpectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negativesplash10-0006-0001092010-1dcbca7a5ffe61f23e50Spectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negativesplash10-004i-0028900000-764e3ecea72fe178a87eSpectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negativesplash10-004i-0018900000-3b774fba9b96129baa6cSpectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-ITFT (LTQ Orbitrap XL, Thermo Scientfic) , Negativesplash10-0006-0000090000-d4236efb9eec36017416Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-03di-0000009000-3cb1cc8e613a3e179149Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-014j-0000009000-4bd400c0be81ab938465Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0006-6920102000-5fc300f474c5dc2b8600Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-03di-0000009000-96d7faa48cdd181798a0Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-03di-1100109000-f496601a0ac75ae3d4a5Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-003s-9201000000-c06274c9b4d1b70a9ce2Spectrum
NMR
TypeDescriptionView
1D NMR1H NMR SpectrumSpectrum
1D NMR1H NMR SpectrumSpectrum
1D NMR1H NMR SpectrumSpectrum
1D NMR1H NMR SpectrumSpectrum
1D NMR13C NMR SpectrumSpectrum
2D NMR[1H,1H] 2D NMR SpectrumSpectrum
2D NMR[1H,13C] 2D NMR SpectrumSpectrum
Pathways
Pathways
Protein Targets
Enzymes
Protein NameGene NameLocusUniprot IDDetails
Pyruvate dehydrogenase E1 component subunit beta, mitochondrialPDHB3p21.1-p14.2P11177 details
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrialPDHA1Xp22.1P08559 details
Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrialPDHA24q22-q23P29803 details
Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrialALDH6A114q24.3Q02252 details
Dihydrolipoyl dehydrogenase, mitochondrialDLD7q31-q32P09622 details
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrialDLAT11q23.1P10515 details
Aldo-keto reductase family 1 member C4AKR1C410p15.1P17516 details
15-hydroxyprostaglandin dehydrogenase [NAD(+)]HPGD4q34-q35P15428 details
TyrosinaseTYR11q14-q21P14679 details
Aldose reductaseAKR1B17q35P15121 details
Short-chain specific acyl-CoA dehydrogenase, mitochondrialACADS12q24.31P16219 details
NADH-ubiquinone oxidoreductase chain 1MT-ND1P03886 details
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1NDUFB114q32.12O75438 details
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1ENPP16q22-q23P22413 details
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrialNDUFS21q23O75306 details
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12NDUFA1212q22Q9UI09 details
NADH-cytochrome b5 reductase 3CYB5R322q13.2P00387 details
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1NDUFA1O15239 details
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2NDUFA4L212q13.3Q9NRX3 details
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3NDUFA319q13.42O95167 details
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8NDUFA89q33.2P51970 details
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4NDUFA47p21.3O00483 details
NADH-ubiquinone oxidoreductase chain 4LMT-ND4LP03901 details
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11NDUFA1119p13.3Q86Y39 details
Lathosterol oxidaseSC5DL11q23.3O75845 details
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrialNDUFS45q11.1O43181 details
Ribosyldihydronicotinamide dehydrogenase [quinone]NQO26p25.2P16083 details
NADH-ubiquinone oxidoreductase chain 5MT-ND5P03915 details
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrialNDUFS311p11.11O75489 details
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5NDUFS51p34.2-p33O43920 details
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrialNDUFV218p11.22P19404 details
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrialNDUFA102q37.3O95299 details
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6NDUFA622q13.2P56556 details
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4NDUFB43q13.33O95168 details
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrialNDUFS811q13O00217 details
NADH-ubiquinone oxidoreductase chain 2MT-ND2P03891 details
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrialALDH4A11p36P30038 details
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7NDUFA719p13.2O95182 details
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2NDUFA25q31O43678 details
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrialNDUFS12q33-q34P28331 details
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrialNDUFB53q26.33O43674 details
NADH dehydrogenase [ubiquinone] 1 subunit C2NDUFC211q14.1O95298 details
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3NDUFB32q31.3O43676 details
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7NDUFB719p13.12P17568 details
Acyl carrier protein, mitochondrialNDUFAB116p12.2O14561 details
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5NDUFA57q32Q16718 details
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrialNDUFA912p13.3Q16795 details
NADH-ubiquinone oxidoreductase chain 4MT-ND4P03905 details
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrialNDUFS719p13.3O75251 details
Xanthine dehydrogenase/oxidaseXDH2p23.1P47989 details
NADH-ubiquinone oxidoreductase chain 3MT-ND3P03897 details
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrialNDUFV111q13P49821 details
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9NDUFB98q13.3Q9Y6M9 details
Methylenetetrahydrofolate reductaseMTHFR1p36.3P42898 details
NADH-ubiquinone oxidoreductase chain 6MT-ND6P03923 details
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13NDUFA1319p13.2Q9P0J0 details
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrialNDUFS65p15.33O75380 details
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3ENPP36q22O14638 details
Glutathione reductase, mitochondrialGSR8p21.1P00390 details
Retinal dehydrogenase 1ALDH1A19q21.13P00352 details
Retinal dehydrogenase 2ALDH1A215q21.3O94788 details
Deoxyhypusine synthaseDHPS19p13.2P49366 details
Succinate-semialdehyde dehydrogenase, mitochondrialALDH5A16p22P51649 details
Squalene synthaseFDFT18p23.1-p22P37268 details
Methylsterol monooxygenase 1MSMO14q32-q34Q15800 details
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylatingNSDHLXq28Q15738 details
4-trimethylaminobutyraldehyde dehydrogenaseALDH9A11q23.1P49189 details
Aldehyde dehydrogenase, dimeric NADP-preferringALDH3A117p11.2P30838 details
Alpha-aminoadipic semialdehyde dehydrogenaseALDH7A15q31P49419 details
Aldehyde dehydrogenase family 1 member A3ALDH1A315q26.3P47895 details
Aldehyde dehydrogenase, mitochondrialALDH212q24.2P05091 details
Fatty aldehyde dehydrogenaseALDH3A217p11.2P51648 details
Aldehyde dehydrogenase X, mitochondrialALDH1B19p11.1P30837 details
Pyrroline-5-carboxylate reductase 1, mitochondrialPYCR117q25.3P32322 details
Pyrroline-5-carboxylate reductase 2PYCR21q42.12Q96C36 details
KynureninaseKYNU2q22.2Q16719 details
Nicotinamide mononucleotide adenylyltransferase 1NMNAT11p36.22Q9HAN9 details
Nicotinamide mononucleotide adenylyltransferase 3NMNAT33q23Q96T66 details
Nicotinate-nucleotide pyrophosphorylase [carboxylating]QPRT16p11.2Q15274 details
Nicotinamide mononucleotide adenylyltransferase 2NMNAT21q25Q9BZQ4 details
Aldo-keto reductase family 1 member C3AKR1C310p15-p14P42330 details
3-hydroxyacyl-CoA dehydrogenase type-2HSD17B10Xp11.2Q99714 details
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrialHADH4q22-q26Q16836 details
GDP-mannose 4,6 dehydrataseGMDS6p25O60547 details
Aldo-keto reductase family 1 member C1AKR1C110p15-p14Q04828 details
Aldo-keto reductase family 1 member C2AKR1C210p15-p14P52895 details
Glyoxylate reductase/hydroxypyruvate reductaseGRHPR9q12Q9UBQ7 details
3-hydroxyisobutyrate dehydrogenase, mitochondrialHIBADH7p15.2P31937 details
2-oxoglutarate dehydrogenase, mitochondrialOGDH7p14-p13Q02218 details
Estradiol 17-beta-dehydrogenase 2HSD17B216q24.1-q24.2P37059 details
Estradiol 17-beta-dehydrogenase 8HSD17B86p21.3Q92506 details
11-cis retinol dehydrogenaseRDH512q13-q14Q92781 details
Sorbitol dehydrogenaseSORD15q15.3Q00796 details
Alcohol dehydrogenase [NADP(+)]AKR1A11p33-p32P14550 details
Alcohol dehydrogenase 4ADH44q22P08319 details
D-beta-hydroxybutyrate dehydrogenase, mitochondrialBDH13q29Q02338 details
Aldehyde dehydrogenase family 3 member B2ALDH3B211q13P48448 details
Aldehyde dehydrogenase family 3 member B1ALDH3B111q13P43353 details
Dihydropteridine reductaseQDPR4p15.31P09417 details
Estradiol 17-beta-dehydrogenase 11HSD17B114q22.1Q8NBQ5 details
7-dehydrocholesterol reductaseDHCR711q13.4Q9UBM7 details
Putative adenosylhomocysteinase 3AHCYL27q32.1Q96HN2 details
AdenosylhomocysteinaseAHCY20q11.22P23526 details
Putative adenosylhomocysteinase 2AHCYL11p13.2O43865 details
Glutamate dehydrogenase 2, mitochondrialGLUD2Xq24-q25P49448 details
Aminomethyltransferase, mitochondrialAMT3p21.2-p21.1P48728 details
Glyceraldehyde-3-phosphate dehydrogenase, testis-specificGAPDHS19q13.12O14556 details
Glutamate dehydrogenase 1, mitochondrialGLUD110q23.3P00367 details
Glyceraldehyde-3-phosphate dehydrogenaseGAPDH12p13P04406 details
Biliverdin reductase ABLVRA7p13P53004 details
Flavin reductase (NADPH)BLVRB19q13.1-q13.2P30043 details
Adenylate cyclase type 7ADCY716q12.1P51828 details
Adenylate cyclase type 4ADCY414q12Q8NFM4 details
Adenylate cyclase type 6ADCY612q12-q13O43306 details
Adenylate cyclase type 5ADCY53q21.1O95622 details
Adenylate cyclase type 8ADCY88q24P40145 details
Adenylate cyclase type 9ADCY916p13.3O60503 details
Adenylate cyclase type 3ADCY32p23.3O60266 details
Adenylate cyclase type 1ADCY17p13-p12Q08828 details
Corticosteroid 11-beta-dehydrogenase isozyme 2HSD11B216q22P80365 details
Corticosteroid 11-beta-dehydrogenase isozyme 1HSD11B11q32-q41P28845 details
Alcohol dehydrogenase class-3ADH54q23P11766 details
Alcohol dehydrogenase 1BADH1B4q23P00325 details
Alcohol dehydrogenase class 4 mu/sigma chainADH74q23-q24P40394 details
Alcohol dehydrogenase 1AADH1A4q23P07327 details
Alcohol dehydrogenase 6ADH64q23P28332 details
Alcohol dehydrogenase 1CADH1C4q23P00326 details
Dihydrofolate reductaseDHFR5q11.2-q13.2P00374 details
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmicGPD112q12-q13P21695 details
Estradiol 17-beta-dehydrogenase 1HSD17B117q11-q21P14061 details
3-keto-steroid reductaseHSD17B71q23P56937 details
Alpha-aminoadipic semialdehyde synthase, mitochondrialAASS7q31.3Q9UDR5 details
Malate dehydrogenase, mitochondrialMDH27cen-q22P40926 details
Malate dehydrogenase, cytoplasmicMDH12p13.3P40925 details
Inosine-5'-monophosphate dehydrogenase 2IMPDH23p21.2P12268 details
Inosine-5'-monophosphate dehydrogenase 1IMPDH17q31.3-q32P20839 details
L-lactate dehydrogenase A-like 6ALDHAL6A11p15.1Q6ZMR3 details
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrialIDH3B20p13O43837 details
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrialIDH3A15q25.1-q25.2P50213 details
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrialIDH3GXq28P51553 details
Tankyrase-2TNKS210q23.3Q9H2K2 details
dTDP-D-glucose 4,6-dehydrataseTGDS13q32.1O95455 details
NAD-dependent protein deacetylase sirtuin-6SIRT619p13.3Q8N6T7 details
UDP-glucose 4-epimeraseGALE1p36-p35Q14376 details
Poly [ADP-ribose] polymerase 3PARP33p21.31-p21.1Q9Y6F1 details
Ecto-ADP-ribosyltransferase 3ART34p15.1-p14Q13508 details
UDP-glucose 6-dehydrogenaseUGDH4p15.1O60701 details
Ecto-ADP-ribosyltransferase 5ART511p15.4Q96L15 details
GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1ART111p15P52961 details
NAD(P) transhydrogenase, mitochondrialNNT5p12Q13423 details
Tankyrase-1TNKS8p23.1O95271 details
Poly [ADP-ribose] polymerase 1PARP11q41-q42P09874 details
Urocanate hydrataseUROC13q21.3Q96N76 details
ADP-ribosyl cyclase 2BST14p15Q10588 details
Poly [ADP-ribose] polymerase 2PARP214q11.2-q12Q9UGN5 details
NAD kinaseNADK1p36.33O95544 details
ADP-ribosyl cyclase 1CD384p15P28907 details
Ecto-ADP-ribosyltransferase 4ART412p13-p12Q93070 details
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrialMTHFD22p13.1P13995 details
Adenylate cyclase type 2ADCY25p15.3Q08462 details
D-3-phosphoglycerate dehydrogenasePHGDH1p12O43175 details
C-1-tetrahydrofolate synthase, cytoplasmicMTHFD114q24P11586 details
Poly [ADP-ribose] polymerase 4PARP413q11Q9UKK3 details
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrialNDUFB11Q9NX14 details
Prostaglandin reductase 1PTGR19q31.3Q14914 details
NAD(P)H dehydrogenase [quinone] 1NQO116q22.1P15559 details
Proline dehydrogenase 1, mitochondrialPRODH22q11.21O43272 details
Kynurenine 3-monooxygenaseKMO1q42-q44O15229 details
17-beta-hydroxysteroid dehydrogenase type 6HSD17B612q13O14756 details
Pyrroline-5-carboxylate reductase 3PYCRL8q24.3Q53H96 details
Retinol dehydrogenase 16RDH1612q13.3O75452 details
Glycine cleavage system H protein, mitochondrialGCSHP23434 details
Dual oxidase 2DUOX215q15.3Q9NRD8 details
UDP-glucuronic acid decarboxylase 1UXS12q12.2Q8NBZ7 details
Glutamine-dependent NAD(+) synthetaseNADSYN111q13.4Q6IA69 details
L-lactate dehydrogenase B chainLDHB12p12.2-p12.1P07195 details
L-lactate dehydrogenase C chainLDHC11p15.1P07864 details
L-lactate dehydrogenase A chainLDHA11p15.4P00338 details
L-lactate dehydrogenase A-like 6BLDHAL6B15q22.2Q9BYZ2 details
Nicotinamide riboside kinase 1NMRK19q21.13Q9NWW6 details
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1HSD3B11p13.1P14060 details
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2HSD3B21p13.1P26439 details
3 beta-hydroxysteroid dehydrogenase type 7HSD3B716p11.2Q9H2F3 details
Inositol-3-phosphate synthase 1ISYNA119p13.11Q9NPH2 details
Dual oxidase 1DUOX115q15.3Q9NRD9 details
3-hydroxybutyrate dehydrogenase type 2BDH24q24Q9BUT1 details
Glycerol-3-phosphate dehydrogenase 1-like proteinGPD1L3p22.3Q8N335 details
Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2MTHFD2L4q13.3Q9H903 details
NADH-cytochrome b5 reductase 1CYB5R11q32.1Q9UHQ9 details
NADH-cytochrome b5 reductase 2CYB5R211p15.4Q6BCY4 details
Cytochrome b5 reductase 4CYB5R46pter-q22.33Q7L1T6 details
NADH-cytochrome b5 reductase-likeCYB5RL1p32.3Q6IPT4 details
Probable saccharopine dehydrogenaseSCCPDH1q44Q8NBX0 details
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolaseMTHFD22p13.1Q7Z650 details
Kynurenine formamidaseAFMID17q25.3Q63HM1 details
Acyl-CoA synthetase family member 4AASDH4q12Q4L235 details
Aminoadipate-semialdehyde synthaseAASS7q31.3A4D0W4 details
Peroxisomal NADH pyrophosphatase NUDT12NUDT125q21.2Q9BQG2 details
Inosine-5'-monophosphate dehydrogenaseIMPDH17q31.3-q32A4D0Z6 details
Metalloreductase STEAP3STEAP32q14.2Q658P3 details
All-trans-retinol 13,14-reductaseRETSAT2p11.2Q6NUM9 details
Metalloreductase STEAP1STEAP17q21Q9UHE8 details
Metalloreductase STEAP2STEAP27q21Q8NFT2 details
Metalloreductase STEAP4STEAP47q21.12Q687X5 details
Peroxisomal coenzyme A diphosphatase NUDT7NUDT716q23.1P0C024 details
Aldehyde dehydrogenase family 8 member A1ALDH8A16q23.2Q9H2A2 details
Putative L-aspartate dehydrogenaseASPDH19q13.33A6ND91 details
Estradiol 17-beta-dehydrogenase 12HSD17B1211p11.2Q53GQ0 details
17-beta-hydroxysteroid dehydrogenase 14HSD17B1419q13.33Q9BPX1 details
Nicotinamide phosphoribosyltransferaseNAMPT7q22.3P43490 details
Nicotinamide riboside kinase 2NMRK219p13.3Q9NPI5 details
Poly [ADP-ribose] polymerase 10PARP108q24.3Q53GL7 details
Poly [ADP-ribose] polymerase 11PARP1112p13.3Q9NR21 details
Poly [ADP-ribose] polymerase 12PARP127q34Q9H0J9 details
Poly [ADP-ribose] polymerase 14PARP143q21.1Q460N5 details
Poly [ADP-ribose] polymerase 15PARP153q21.1Q460N3 details
Mono [ADP-ribose] polymerase PARP16PARP1615q22.31Q8N5Y8 details
Poly [ADP-ribose] polymerase 6PARP615q23Q2NL67 details
Poly [ADP-ribose] polymerase 8PARP85q11.1Q8N3A8 details
Poly [ADP-ribose] polymerase 9PARP93q21Q8IXQ6 details
TCDD-inducible poly [ADP-ribose] polymeraseTIPARP3q25.31Q7Z3E1 details
Nicotinate phosphoribosyltransferaseNAPRT18q24.3Q6XQN6 details
Prostaglandin reductase 2PTGR214q24.3Q8N8N7 details
NAD-dependent protein deacetylase sirtuin-1SIRT110q21.3Q96EB6 details
NAD-dependent protein deacetylase sirtuin-2SIRT219q13Q8IXJ6 details
NAD-dependent protein deacetylase sirtuin-3, mitochondrialSIRT311p15.5Q9NTG7 details
NAD-dependent protein deacetylase sirtuin-4SIRT412qQ9Y6E7 details
NAD-dependent protein deacylase sirtuin-5, mitochondrialSIRT56p23Q9NXA8 details
NAD-dependent protein deacetylase sirtuin-7SIRT717q25Q9NRC8 details
tRNA 2'-phosphotransferase 1TRPT111q13.1Q86TN4 details
2-oxoglutarate dehydrogenase-like, mitochondrialOGDHLQ9ULD0 details
NADH dehydrogenase (Ubiquinone) 1 beta subcomplex, 2, 8kDaNDUFB27q34A4D1T5 details
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferaseAASDHPPT11q22Q9NRN7 details
14 kDa phosphohistidine phosphatasePHPT1Q9NRX4 details
Aldo-keto reductase family 1 member B10AKR1B10O60218 details
Dihydrofolate reductase, mitochondrialDHFRL13q11.1Q86XF0 details
NAD kinase domain-containing protein 1, mitochondrialNADKD15p13.2Q4G0N4 details
Epidermal retinol dehydrogenase 2SDR16C58q12.1Q8N3Y7 details
Transporters
Protein NameGene NameLocusUniprot IDDetails
Aldo-keto reductase family 1 member C4AKR1C410p15.1P17516 details
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11NDUFA1119p13.3Q86Y39 details
Acyl carrier protein, mitochondrialNDUFAB116p12.2O14561 details
Putative adenosylhomocysteinase 2AHCYL11p13.2O43865 details
Tricarboxylate transport protein, mitochondrialSLC25A122q11.21P53007 details
Transient receptor potential cation channel subfamily M member 2TRPM221q22.3O94759 details
Glycerol-3-phosphate dehydrogenase 1-like proteinGPD1L3p22.3Q8N335 details
Acyl-CoA synthetase family member 4AASDH4q12Q4L235 details
Metal Bindings
Protein NameGene NameLocusUniprot IDDetails
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1ENPP16q22-q23P22413 details
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrialNDUFS21q23O75306 details
Lathosterol oxidaseSC5DL11q23.3O75845 details
Ribosyldihydronicotinamide dehydrogenase [quinone]NQO26p25.2P16083 details
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrialNDUFV218p11.22P19404 details
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrialNDUFS811q13O00217 details
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrialNDUFS12q33-q34P28331 details
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrialNDUFS719p13.3O75251 details
Xanthine dehydrogenase/oxidaseXDH2p23.1P47989 details
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrialNDUFV111q13P49821 details
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3ENPP36q22O14638 details
Methylsterol monooxygenase 1MSMO14q32-q34Q15800 details
Cytochrome P450 4A11CYP4A111p33Q02928 details
Sorbitol dehydrogenaseSORD15q15.3Q00796 details
Alcohol dehydrogenase 4ADH44q22P08319 details
Biliverdin reductase ABLVRA7p13P53004 details
Adenylate cyclase type 7ADCY716q12.1P51828 details
Adenylate cyclase type 4ADCY414q12Q8NFM4 details
Adenylate cyclase type 6ADCY612q12-q13O43306 details
Adenylate cyclase type 5ADCY53q21.1O95622 details
Adenylate cyclase type 8ADCY88q24P40145 details
Adenylate cyclase type 9ADCY916p13.3O60503 details
Adenylate cyclase type 3ADCY32p23.3O60266 details
Adenylate cyclase type 1ADCY17p13-p12Q08828 details
Alcohol dehydrogenase class-3ADH54q23P11766 details
Alcohol dehydrogenase 1BADH1B4q23P00325 details
Alcohol dehydrogenase class 4 mu/sigma chainADH74q23-q24P40394 details
Alcohol dehydrogenase 1AADH1A4q23P07327 details
Alcohol dehydrogenase 6ADH64q23P28332 details
Alcohol dehydrogenase 1CADH1C4q23P00326 details
NADP-dependent malic enzymeME16q12P48163 details
NADP-dependent malic enzyme, mitochondrialME311cen-q22.3Q16798 details
NAD-dependent malic enzyme, mitochondrialME218q21P23368 details
Inosine-5'-monophosphate dehydrogenase 2IMPDH23p21.2P12268 details
Inosine-5'-monophosphate dehydrogenase 1IMPDH17q31.3-q32P20839 details
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrialIDH3B20p13O43837 details
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrialIDH3A15q25.1-q25.2P50213 details
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrialIDH3GXq28P51553 details
Tankyrase-2TNKS210q23.3Q9H2K2 details
NAD-dependent protein deacetylase sirtuin-6SIRT619p13.3Q8N6T7 details
Tankyrase-1TNKS8p23.1O95271 details
Poly [ADP-ribose] polymerase 1PARP11q41-q42P09874 details
NAD kinaseNADK1p36.33O95544 details
Adenylate cyclase type 2ADCY25p15.3Q08462 details
Prostaglandin reductase 1PTGR19q31.3Q14914 details
Dual oxidase 2DUOX215q15.3Q9NRD8 details
Nicotinamide riboside kinase 1NMRK19q21.13Q9NWW6 details
Dual oxidase 1DUOX115q15.3Q9NRD9 details
Cytochrome b5 reductase 4CYB5R46pter-q22.33Q7L1T6 details
Cytochrome P450 4A22CYP4A221p33Q5TCH4 details
Peroxisomal NADH pyrophosphatase NUDT12NUDT125q21.2Q9BQG2 details
Metalloreductase STEAP3STEAP32q14.2Q658P3 details
Metalloreductase STEAP1STEAP17q21Q9UHE8 details
Metalloreductase STEAP2STEAP27q21Q8NFT2 details
Metalloreductase STEAP4STEAP47q21.12Q687X5 details
Peroxisomal coenzyme A diphosphatase NUDT7NUDT716q23.1P0C024 details
Nicotinamide riboside kinase 2NMRK219p13.3Q9NPI5 details
Poly [ADP-ribose] polymerase 12PARP127q34Q9H0J9 details
TCDD-inducible poly [ADP-ribose] polymeraseTIPARP3q25.31Q7Z3E1 details
Prostaglandin reductase 2PTGR214q24.3Q8N8N7 details
NAD-dependent protein deacetylase sirtuin-1SIRT110q21.3Q96EB6 details
NAD-dependent protein deacetylase sirtuin-2SIRT219q13Q8IXJ6 details
NAD-dependent protein deacetylase sirtuin-3, mitochondrialSIRT311p15.5Q9NTG7 details
NAD-dependent protein deacetylase sirtuin-4SIRT412qQ9Y6E7 details
NAD-dependent protein deacylase sirtuin-5, mitochondrialSIRT56p23Q9NXA8 details
NAD-dependent protein deacetylase sirtuin-7SIRT717q25Q9NRC8 details
L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferaseAASDHPPT11q22Q9NRN7 details
Receptors
Protein NameGene NameLocusUniprot IDDetails
15-hydroxyprostaglandin dehydrogenase [NAD(+)]HPGD4q34-q35P15428 details
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1ENPP16q22-q23P22413 details
Ectonucleotide pyrophosphatase/phosphodiesterase family member 3ENPP36q22O14638 details
Retinal dehydrogenase 2ALDH1A215q21.3O94788 details
Aldo-keto reductase family 1 member C3AKR1C310p15-p14P42330 details
Aldo-keto reductase family 1 member C2AKR1C210p15-p14P52895 details
Adenylate cyclase type 7ADCY716q12.1P51828 details
Adenylate cyclase type 4ADCY414q12Q8NFM4 details
Adenylate cyclase type 6ADCY612q12-q13O43306 details
Adenylate cyclase type 5ADCY53q21.1O95622 details
Adenylate cyclase type 8ADCY88q24P40145 details
Adenylate cyclase type 9ADCY916p13.3O60503 details
Adenylate cyclase type 3ADCY32p23.3O60266 details
Adenylate cyclase type 1ADCY17p13-p12Q08828 details
Alcohol dehydrogenase class 4 mu/sigma chainADH74q23-q24P40394 details
Tankyrase-2TNKS210q23.3Q9H2K2 details
Tankyrase-1TNKS8p23.1O95271 details
Poly [ADP-ribose] polymerase 1PARP11q41-q42P09874 details
ADP-ribosyl cyclase 1CD384p15P28907 details
Adenylate cyclase type 2ADCY25p15.3Q08462 details
Transient receptor potential cation channel subfamily M member 2TRPM221q22.3O94759 details
TCDD-inducible poly [ADP-ribose] polymeraseTIPARP3q25.31Q7Z3E1 details
NAD-dependent protein deacetylase sirtuin-1SIRT110q21.3Q96EB6 details
14 kDa phosphohistidine phosphatasePHPT1Q9NRX4 details
Myotubularin-related protein 2MTMR2Q13614 details
Transcriptional Factors
Protein NameGene NameLocusUniprot IDDetails
Dihydrofolate reductaseDHFR5q11.2-q13.2P00374 details
NAD-dependent protein deacetylase sirtuin-6SIRT619p13.3Q8N6T7 details
Tankyrase-1TNKS8p23.1O95271 details
Poly [ADP-ribose] polymerase 1PARP11q41-q42P09874 details
ADP-ribosyl cyclase 1CD384p15P28907 details
Forkhead box protein O4FOXO4P98177 details
Nicotinamide phosphoribosyltransferaseNAMPT7q22.3P43490 details
Poly [ADP-ribose] polymerase 14PARP143q21.1Q460N5 details
Poly [ADP-ribose] polymerase 15PARP153q21.1Q460N3 details
NAD-dependent protein deacetylase sirtuin-1SIRT110q21.3Q96EB6 details
NAD-dependent protein deacetylase sirtuin-2SIRT219q13Q8IXJ6 details
NAD-dependent protein deacetylase sirtuin-3, mitochondrialSIRT311p15.5Q9NTG7 details
NAD-dependent protein deacetylase sirtuin-4SIRT412qQ9Y6E7 details
NAD-dependent protein deacylase sirtuin-5, mitochondrialSIRT56p23Q9NXA8 details
NAD-dependent protein deacetylase sirtuin-7SIRT717q25Q9NRC8 details
Concentrations Data
Not Available
HMDB IDHMDB0000902
DrugBank IDDB14128
Phenol Explorer Compound IDNot Available
FoodDB IDFDB022309
KNApSAcK IDC00007256
Chemspider ID5682
KEGG Compound IDC00003
BioCyc IDNAD
BiGG IDNot Available
Wikipedia LinkNicotinamide_adenine_dinucleotide
METLIN IDNot Available
PubChem Compound5892
PDB IDNot Available
ChEBI ID44215
References
General ReferencesNot Available

Only showing the first 10 proteins. There are 353 proteins in total.

Enzymes

General function:
Involved in catalytic activity
Specific function:
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
Gene Name:
PDHB
Uniprot ID:
P11177
Molecular weight:
39233.1
General function:
Involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Specific function:
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
Gene Name:
PDHA1
Uniprot ID:
P08559
Molecular weight:
43295.255
General function:
Involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Specific function:
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
Gene Name:
PDHA2
Uniprot ID:
P29803
Molecular weight:
42932.855
General function:
Involved in oxidoreductase activity
Specific function:
Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.
Gene Name:
ALDH6A1
Uniprot ID:
Q02252
Molecular weight:
57839.31
General function:
Involved in oxidoreductase activity
Specific function:
Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction.
Gene Name:
DLD
Uniprot ID:
P09622
Molecular weight:
54176.91
General function:
Involved in acyltransferase activity
Specific function:
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
Gene Name:
DLAT
Uniprot ID:
P10515
Molecular weight:
68996.03
General function:
Involved in oxidoreductase activity
Specific function:
Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
Gene Name:
AKR1C4
Uniprot ID:
P17516
Molecular weight:
37094.57
General function:
Involved in oxidoreductase activity
Specific function:
Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.
Gene Name:
HPGD
Uniprot ID:
P15428
Molecular weight:
28977.105
General function:
Involved in oxidoreductase activity
Specific function:
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.
Gene Name:
TYR
Uniprot ID:
P14679
Molecular weight:
60392.69
General function:
Involved in oxidoreductase activity
Specific function:
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
Gene Name:
AKR1B1
Uniprot ID:
P15121
Molecular weight:
35853.125

Transporters

General function:
Involved in oxidoreductase activity
Specific function:
Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
Gene Name:
AKR1C4
Uniprot ID:
P17516
Molecular weight:
37094.57
General function:
Involved in protein transporter activity
Specific function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Gene Name:
NDUFA11
Uniprot ID:
Q86Y39
Molecular weight:
14852.0
General function:
Involved in acyl carrier activity
Specific function:
Carrier of the growing fatty acid chain in fatty acid biosynthesis in mitochondria. Accessory and non-catalytic subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain
Gene Name:
NDUFAB1
Uniprot ID:
O14561
Molecular weight:
17417.1
General function:
Involved in adenosylhomocysteinase activity
Specific function:
Not Available
Gene Name:
AHCYL1
Uniprot ID:
O43865
Molecular weight:
53753.0
General function:
Involved in transporter activity
Specific function:
Involved in citrate-H(+)/malate exchange. Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD+ for the glycolytic pathway
Gene Name:
SLC25A1
Uniprot ID:
P53007
Molecular weight:
34012.5
General function:
Involved in ion channel activity
Specific function:
Nonselective, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress. Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation. Activated by ADP-ribose, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid. Inactivated by intracellular ATP. Confers susceptibility to cell death following oxidative stress. Isoform 2 does not seem to be regulated by ADPR. Has ADP-ribose pyrophosphatase activity.
Gene Name:
TRPM2
Uniprot ID:
O94759
Molecular weight:
171224.9
General function:
Involved in oxidoreductase activity
Specific function:
Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L.
Gene Name:
GPD1L
Uniprot ID:
Q8N335
Molecular weight:
38418.44
General function:
Involved in acyl carrier activity
Specific function:
Acyl-CoA synthases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA
Gene Name:
AASDH
Uniprot ID:
Q4L235
Molecular weight:
122596.1

Only showing the first 10 proteins. There are 353 proteins in total.