Identification
HMDB Protein ID CDBP00168
Secondary Accession Numbers Not Available
Name NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7
Description Not Available
Synonyms
  1. CI-B18
  2. Cell adhesion protein SQM1
  3. Complex I-B18
  4. NADH-ubiquinone oxidoreductase B18 subunit
Gene Name NDUFB7
Protein Type Enzyme
Biological Properties
General Function Involved in NADH dehydrogenase activity
Specific Function Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
GO Classification
Component
intracellular membrane-bounded organelle
mitochondrion
organelle
membrane-bounded organelle
Function
catalytic activity
nadh dehydrogenase activity
nadh dehydrogenase (quinone) activity
nadh dehydrogenase (ubiquinone) activity
oxidoreductase activity
oxidoreductase activity, acting on nadh or nadph
Cellular Location
  1. Peripheral membrane protein
  2. Mitochondrion inner membrane
  3. Matrix side
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 19p13.12
SNPs NDUFB7
Gene Sequence
>414 bp
ATGGGGGCCCACCTGGTCCGGCGCTACCTGGGCGATGCCTCGGTGGAGCCCGACCCCCTG
CAGATGCCAACCTTCCCGCCAGACTACGGCTTCCCCGAACGCAAGGAGCGCGAGATGGTG
GCCACACAGCAGGAGATGATGGACGCGCAGCTGAGGCTCCAGCTGCGGGACTACTGCGCC
CACCACCTCATCCGGCTGCTCAAGTGCAAGCGTGACAGCTTCCCCAACTTCCTGGCCTGC
AAGCAGGAGCGGCACGACTGGGACTACTGCGAGCACCGCGACTATGTGATGCGCATGAAG
GAGTTTGAGCGGGAGCGGAGGCTGCTCCAGCGGAAGAAGCGGCGGGAGAAGAAGGCGGCA
GAGTTGGCCAAAGGCCAGGGACCCGGGGAAGTGGACCCCAAGGTGGCCCTGTAG
Protein Properties
Number of Residues 137
Molecular Weight 16401.8
Theoretical pI 9.21
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7
MGAHLVRRYLGDASVEPDPLQMPTFPPDYGFPERKEREMVATQQEMMDAQLRLQLRDYCA
HHLIRLLKCKRDSFPNFLACKQERHDWDYCEHRDYVMRMKEFERERRLLQRKKRREKKAA
ELAKGQGPGEVDPKVAL
GenBank ID Protein 6563188
UniProtKB/Swiss-Prot ID P17568
UniProtKB/Swiss-Prot Entry Name NDUB7_HUMAN
PDB IDs Not Available
GenBank Gene ID AF112200
GeneCard ID NDUFB7
GenAtlas ID NDUFB7
HGNC ID HGNC:7702
References
General References Not Available