Cannabis Compound Database: Showing Protein Alcohol dehydrogenase 4 (CDBP00490)

Identification Biological properties Gene properties Protein properties External links References XML Show 10 compounds

Identification

HMDB Protein ID

CDBP00490

Secondary Accession Numbers

Not Available

Name

Alcohol dehydrogenase 4

Description

Not Available

Synonyms

Alcohol dehydrogenase class II pi chain

Gene Name

ADH4

Protein Type

Enzyme

Biological Properties

General Function

Involved in zinc ion binding

Specific Function

Not Available

GO Classification

Biological Process
alcohol catabolic process
cellular aldehyde metabolic process
quinone cofactor metabolic process
retinol metabolic process
xenobiotic metabolic process
ethanol oxidation
Cellular Component
cytosol
microtubule cytoskeleton
Function
binding
catalytic activity
transition metal ion binding
zinc ion binding
oxidoreductase activity
ion binding
cation binding
metal ion binding
Molecular Function
NAD binding
alcohol dehydrogenase activity, zinc-dependent
alditol:NADP+ 1-oxidoreductase activity
all-trans retinal binding
benzaldehyde dehydrogenase activity
NADPH:quinone reductase activity
retinol binding
retinol dehydrogenase activity
metal ion binding
zinc ion binding
Process
oxidation reduction
metabolic process

Cellular Location

Cytoplasm

Pathways

Name	SMPDB/Pathwhiz	KEGG
Glycolysis / Gluconeogenesis	Not Available
Metabolism of xenobiotics by cytochrome P450	Not Available
Drug metabolism - cytochrome P450	Not Available
Chemical carcinogenesis	Not Available

Gene Properties

Chromosome Location

Locus

4q22

SNPs

ADH4

Gene Sequence

>1143 bp
ATGGGCACCAAGGGCAAAGTTATTAAATGCAAAGCAGCCATCGCCTGGGAAGCAGGCAAG
CCCCTTTGCATTGAAGAGGTTGAAGTAGCTCCCCCCAAGGCTCATGAAGTTCGCATTCAG
ATCATTGCTACCTCCCTGTGCCATACTGATGCCACTGTTATCGATTCTAAATTTGAGGGC
CTAGCTTTCCCAGTGATCGTTGGCCATGAGGCTGCAGGTATTGTGGAAAGTATTGGGCCA
GGAGTGACCAACGTCAAACCAGGTGACAAAGTAATTCCACTTTATGCACCTCTATGTAGA
AAATGCAAGTTTTGTCTGAGTCCACTCACAAATTTGTGTGGGAAAATCAGTAATCTCAAA
AGTCCTGCTAGTGATCAACAACTAATGGAAGACAAAACCAGCAGGTTTACCTGCAAAGGA
AAACCAGTTTACCATTTCTTTGGAACCAGTACATTCTCTCAGTACACTGTGGTGTCAGAT
ATCAATCTTGCCAAAATAGATGATGATGCAAATTTAGAGAGAGTTTGTCTGCTTGGATGT
GGGTTTTCAACTGGCTATGGGGCTGCAATCAACAATGCCAAGGTCACCCCTGGTTCGACT
TGTGCTGTCTTTGGCCTAGGAGGTGTGGGTCTTTCTGCTGTAATGGGTTGTAAAGCAGCA
GGAGCTTCCAGAATCATAGGTATTGACATCAACAGTGAGAAGTTTGTGAAGGCTAAAGCC
CTGGGAGCCACTGACTGCCTCAATCCTAGAGACTTACATAAACCAATCCAGGAAGTTATC
ATTGAATTGACCAAGGGAGGTGTGGATTTTGCCCTTGACTGTGCAGGTGGATCTGAAACC
ATGAAAGCAGCCCTGGACTGTACAACCGCAGGCTGGGGATCATGTACTTTCATTGGAGTA
GCTGCTGGTAGCAAAGGATTGACTATTTTTCCAGAGGAGCTAATAATCGGCCGTACTATA
AATGGAACATTCTTTGGTGGTTGGAAAAGTGTAGATTCTATCCCAAAGCTGGTCACTGAC
TATAAGAATAAGAAATTCAATCTGGATGCATTGGTGACCCATACCCTGCCTTTTGACAAA
ATCAGTGAGGCATTTGACCTAATGAACCAAGGAAAAAGCGTCCGAACAATCCTCATCTTT
TGA

Protein Properties

Number of Residues

380

Molecular Weight

40221.335

Theoretical pI

7.936

Pfam Domain Function

ADH_zinc_N (PF00107 )
ADH_N (PF08240 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Alcohol dehydrogenase 4
MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG
LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK
SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC
GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA
LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV
AAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK
ISEAFDLMNQGKSVRTILIF

External Links

GenBank ID Protein

158255106

UniProtKB/Swiss-Prot ID

P08319

UniProtKB/Swiss-Prot Entry Name

ADH4_HUMAN

PDB IDs