| Identification |
|---|
| HMDB Protein ID
| CDBP00730 |
| Secondary Accession Numbers
| Not Available |
| Name
| Alcohol dehydrogenase 6 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| ADH6 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in zinc ion binding |
| Specific Function
| Not Available |
| GO Classification
|
| Biological Process |
| response to ethanol |
| xenobiotic metabolic process |
| ethanol oxidation |
| Cellular Component |
| cytosol |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| catalytic activity |
| transition metal ion binding |
| zinc ion binding |
| oxidoreductase activity |
| Molecular Function |
| alcohol dehydrogenase (NAD) activity |
| metal ion binding |
| zinc ion binding |
| nucleotide binding |
| Process |
| metabolic process |
| oxidation reduction |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Glycolysis / Gluconeogenesis | Not Available |  | | Metabolism of xenobiotics by cytochrome P450 | Not Available |  | | Drug metabolism - cytochrome P450 | Not Available |  | | Chemical carcinogenesis | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| 4 |
| Locus
| 4q23 |
| SNPs
| ADH6 |
| Gene Sequence
|
>1107 bp
ATGAGTACTACAGGCCAAGTCATCAGATGCAAAGCAGCCATACTCTGGAAGCCTGGTGCA
CCATTTTCTATTGAAGAGGTAGAAGTGGCCCCACCAAAGGCAAAGGAAGTTCGCATAAAG
GTTGTGGCCACCGGACTGTGTGGTACAGAGATGAAAGTGTTGGGGAGTAAACACTTGGAC
CTCTTGTATCCCACCATCTTGGGCCATGAAGGGGCTGGAATCGTTGAGAGTATTGGAGAA
GGAGTAAGCACAGTGAAACCAGGTGACAAAGTTATCACACTCTTTCTGCCACAGTGTGGA
GAATGTACCTCTTGCCTGAATTCTGAGGGCAATTTTTGTATACAATTCAAACAGTCAAAA
ACCCAACTGATGTCTGATGGTACCAGCAGGTTTACCTGCAAGGGAAAATCAATATATCAC
TTTGGTAATACCAGCACCTTCTGTGAATACACAGTGATAAAGGAAATCTCAGTTGCCAAG
ATTGATGCAGTCGCTCCTCTAGAGAAAGTATGCCTAATTAGCTGTGGCTTTTCCACTGGG
TTTGGTGCTGCAATCAATACTGCCAAGGTGACTCCAGGTTCTACCTGTGCTGTGTTTGGC
CTGGGAGGAGTCGGCTTGTCTGTTGTCATGGGTTGTAAAGCAGCAGGAGCAGCCAGGATC
ATTGGAGTGGATGTCAACAAGGAGAAATTTAAGAAGGCACAGGAATTGGGTGCTACTGAG
TGCCTCAACCCTCAGGACTTAAAGAAACCCATTCAAGAAGTTTTATTTGATATGACAGAT
GCTGGTATAGACTTCTGCTTTGAGGCCATTGGAAATCTGGACGTTCTGGCAGCTGCCCTC
GCCTCCTGCAATGAGAGCTATGGGGTCTGTGTGGTTGTTGGGGTGTTGCCTGCCAGTGTT
CAACTCAAAATCAGTGGCCAGTTGTTCTTCTCAGGACGTTCTTTGAAGGGTTCTGTTTTT
GGAGGCTGGAAGAGCAGACAGCACATCCCTAAACTGGTTGCTGATTATATGGCAGAGAAG
TTGAATCTAGATCCACTAATTACTCATACTCTGAATCTTGATAAAATCAATGAAGCAGTT
GAATTAATGAAAACTGGAAAATGGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 368 |
| Molecular Weight
| 39072.275 |
| Theoretical pI
| 7.796 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Alcohol dehydrogenase 6
MCTTGQVIRCKAAILWKPGAPFSIEEVEVAPPKAKEVRIKVVATGLCGTEMKVLGSKHLD
LLYPTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSK
TQLMSDGTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFSTG
FGAAINTAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGATE
CLNPQDLKKPIQEVLFDMTDAGIDFCFEAIGNLDVLAAALASCNESYGVCVVVGVLPASV
QLKISGQLFFSGRSLKGSVFGGWKSRQHIPKLVADYMAEKLNLDPLITHTLNLDKINEAV
ELMKTGKW
|
| External Links |
|---|
| GenBank ID Protein
| 4501939 |
| UniProtKB/Swiss-Prot ID
| P28332 |
| UniProtKB/Swiss-Prot Entry Name
| ADH6_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_000672.3 |
| GeneCard ID
| ADH6 |
| GenAtlas ID
| ADH6 |
| HGNC ID
| HGNC:255 |
| References |
|---|
| General References
| Not Available |