Identification |
HMDB Protein ID
| CDBP00628 |
Secondary Accession Numbers
| Not Available |
Name
| Putative adenosylhomocysteinase 2 |
Description
| Not Available |
Synonyms
|
- AdoHcyase 2
- DC-expressed AHCY-like molecule
- S-adenosyl-L-homocysteine hydrolase 2
- S-adenosylhomocysteine hydrolase-like protein 1
|
Gene Name
| AHCYL1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in adenosylhomocysteinase activity |
Specific Function
| Not Available |
GO Classification
|
Biological Process |
protein export from nucleus |
regulation of anion transport |
regulation of ion transmembrane transporter activity |
regulation of mRNA 3'-end processing |
mRNA polyadenylation |
one-carbon metabolic process |
positive regulation of sodium ion transport |
Cellular Component |
endoplasmic reticulum |
Function |
catalytic activity |
hydrolase activity |
hydrolase activity, acting on ether bonds |
trialkylsulfonium hydrolase activity |
adenosylhomocysteinase activity |
Molecular Function |
nucleotide binding |
adenosylhomocysteinase activity |
Process |
metabolic process |
cellular metabolic process |
one-carbon metabolic process |
|
Cellular Location
|
- Endoplasmic reticulum
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | L-homocysteine biosynthesis | Not Available | Not Available | Cysteine and methionine metabolism | Not Available | |
|
Gene Properties |
Chromosome Location
| 1 |
Locus
| 1p13.2 |
SNPs
| AHCYL1 |
Gene Sequence
|
>1593 bp
ATGTCGATGCCTGACGCGATGCCGCTGCCCGGGGTCGGGGAGGAGCTGAAGCAGGCCAAG
GAGATCGAGGACGCCGAGAAGTACTCCTTCATGGCCACCGTCACCAAGGCGCCCAAGAAG
CAAATCCAGTTTGCTGATGACATGCAGGAGTTCACCAAATTCCCCACCAAAACTGGCCGA
AGATCTTTGTCTCGCTCGATCTCACAGTCCTCCACTGACAGCTACAGTTCAGCTGCATCC
TACACAGATAGCTCTGATGATGAGGTTTCTCCCCGAGAGAAGCAGCAAACCAACTCCAAG
GGCAGCAGCAATTTCTGTGTGAAGAACATCAAGCAGGCAGAATTTGGACGCCGGGAGATT
GAGATTGCAGAGCAAGACATGTCTGCTCTGATTTCACTCAGGAAACGTGCTCAGGGGGAG
AAGCCCTTGGCTGGTGCTAAAATAGTGGGCTGTACACACATCACAGCCCAGACAGCGGTG
TTGATTGAGACACTCTGTGCCCTGGGGGCTCAGTGCCGCTGGTCTGCTTGTAACATCTAC
TCAACTCAGAATGAAGTAGCTGCAGCACTGGCTGAGGCTGGAGTTGCAGTGTTCGCTTGG
AAGGGCGAGTCAGAAGATGACTTCTGGTGGTGTATTGACCGCTGTGTGAACATGGATGGG
TGGCAGGCCAACATGATCCTGGATGATGGGGGAGACTTAACCCACTGGGTTTATAAGAAG
TATCCAAACGTGTTTAAGAAGATCCGAGGCATTGTGGAAGAGAGCGTGACTGGTGTTCAC
AGGCTGTATCAGCTCTCCAAAGCTGGGAAGCTCTGTGTTCCGGCCATGAACGTCAATGAT
TCTGTTACCAAACAGAAGTTTGATAACTTGTACTGCTGCCGAGAATCCATTTTGGATGGC
CTGAAGAGGACCACAGATGTGATGTTTGGTGGGAAACAAGTGGTGGTGTGTGGCTATGGT
GAGGTAGGCAAGGGCTGCTGTGCTGCTCTCAAAGCTCTTGGAGCAATTGTCTACATTACC
GAAATCGACCCCATCTGTGCTCTGCAGGCCTGCATGGATGGGTTCAGGGTGGTAAAGCTA
AATGAAGTCATCCGGCAAGTCGATGTCGTAATAACTTGCACAGGAAATAAGAATGTAGTG
ACACGGGAGCACTTGGATCGCATGAAAAACAGTTGTATCGTATGCAATATGGGCCACTCC
AACACAGAAATCGATGTGACCAGCCTCCGCACTCCGGAGCTGACGTGGGAGCGAGTACGT
TCTCAGGTGGACCATGTCATCTGGCCAGATGGCAAACGAGTTGTCCTCCTGGCAGAGGGT
CGTCTACTCAATTTGAGCTGCTCCACAGTTCCCACCTTTGTTCTGTCCATCACAGCCACA
ACACAGGCTTTGGCACTGATAGAACTCTATAATGCACCCGAGGGGCGATACAAGCAGGAT
GTGTACTTGCTTCCTAAGAAAATGGATGAATACGTTGCCAGCTTGCATCTGCCATCATTT
GATGCCCACCTTACAGAGCTGACAGATGACCAAGCAAAATATCTGGGACTCAACAAAAAT
GGGCCATTCAAACCTAATTATTACAGATACTAA
|
Protein Properties |
Number of Residues
| 530 |
Molecular Weight
| 53753.0 |
Theoretical pI
| 7.44 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Putative adenosylhomocysteinase 2
MSMPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGR
RSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREI
EIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETLCALGAQCRWSACNIY
STQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKK
YPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDG
LKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL
NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVR
SQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQD
VYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY
|
External Links |
GenBank ID Protein
| 16588687 |
UniProtKB/Swiss-Prot ID
| O43865 |
UniProtKB/Swiss-Prot Entry Name
| SAHH2_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| AF315687 |
GeneCard ID
| AHCYL1 |
GenAtlas ID
| AHCYL1 |
HGNC ID
| HGNC:344 |
References |
General References
| Not Available |