Identification
HMDB Protein ID CDBP02179
Secondary Accession Numbers Not Available
Name Pyrroline-5-carboxylate reductase 3
Description Not Available
Synonyms
  1. P5C reductase 3
  2. P5CR 3
  3. Pyrroline-5-carboxylate reductase-like protein
Gene Name PYCRL
Protein Type Enzyme
Biological Properties
General Function Involved in oxidoreductase activity
Specific Function Not Available
GO Classification
Biological Process
L-proline biosynthetic process
Function
binding
catalytic activity
pyrroline-5-carboxylate reductase activity
oxidoreductase activity, acting on the ch-nh group of donors
oxidoreductase activity, acting on the ch-nh group of donors, nad or nadp as acceptor
oxidoreductase activity
Molecular Function
pyrroline-5-carboxylate reductase activity
nucleotide binding
Process
metabolic process
cellular metabolic process
glutamine family amino acid metabolic process
proline metabolic process
proline biosynthetic process
oxidation reduction
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location 8
Locus 8q24.3
SNPs PYCRL
Gene Sequence
>825 bp
ATGGCAGCTGCGGAGCCGTCTCCGCGGCGCGTGGGCTTCGTGGGCGCGGGCCGCATGGCG
GGGGCCATCGCGCAGGGCCTCATCAGAGCAGGAAAAGTGGAAGCTCAGCACATACTGGCC
AGTGCACCAACAGACAGGAACCTATGTCACTTTCAAGCTCTGGGTTGCCGGACCACGCAC
TCCAACCAGGAGGTGCTGCAGAGCTGCCTGCTCGTCATCTTTGCCACCAAGCCTCATGTG
CTGCCAGCTGTCCTGGCAGAGGTGGCTCCTGTGGTCACCACTGAACACATCTTGGTGTCC
GTGGCTGCTGGGGTGTCTCTGAGCACCCTGGAGGAGCTGCTGCCCCCGAACACACGGGTG
CTGCGGGTCTTGCCCAACCTGCCCTGTGTGGTCCAGGAAGGGGCCATAGTGATGGCGCGG
GGCCGCCACGTGGGGAGCAGCGAGACCAACCTCCTGCAGCATCTGCTGGAGGCCTGTGGG
CGGTGTGAGGAGGTGCCTGAAGCCTACGTCGACATCCACACTGGCCTCAGTGGCAGTGGC
GTGGCCTTCGTGTGTGCATTCTCCGAGGCCCTGGCTGAAGGAGCCGTCAAGATGGGCATG
CCCAGCAGCCTGGCCCACCGCATCGCTGCCCAGACCCTGCTGGGGACGGCCAAGATGCTG
CTGCACGAGGGCCAACACCCAGCCCAGCTGCGCTCAGACGTGTGCACCCCGGGTGGCACC
ACCATCTATGGACTCCACGCCCTGGAGCAGGGCGGGCTGCGAGCAGCCACCATGAGCGCC
GTGGAGGCTGCCACCTGCCGGGCCAAGGAGCTCAGCAGAAAGTAG
Protein Properties
Number of Residues 274
Molecular Weight 29892.415
Theoretical pI 8.109
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Pyrroline-5-carboxylate reductase 3
MAAAEPSPRRVGFVGAGRMAGAIAQGLIRAGKVEAQHILASAPTDRNLCHFQALGCRTTH
SNQEVLQSCLLVIFATKPHVLPAVLAEVAPVVTTEHILVSVAAGVSLSTLEELLPPNTRV
LRVLPNLPCVVQEGAIVMARGRHVGSSETNLLQHLLEACGRCEEVPEAYVDIHTGLSGSG
VAFVCAFSEALAEGAVKMGMPSSLAHRIAAQTLLGTAKMLLHEGQHPAQLRSDVCTPGGT
TIYGLHALEQGGLRAATMSAVEAATCRAKELSRK
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q53H96
UniProtKB/Swiss-Prot Entry Name P5CR3_HUMAN
PDB IDs Not Available
GenBank Gene ID AK001500
GeneCard ID PYCRL
GenAtlas ID PYCRL
HGNC ID HGNC:25846
References
General References Not Available