Identification
HMDB Protein ID CDBP00154
Secondary Accession Numbers Not Available
Name NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
Description Not Available
Synonyms
  1. CI-B8
  2. Complex I-B8
  3. NADH-ubiquinone oxidoreductase B8 subunit
Gene Name NDUFA2
Protein Type Enzyme
Biological Properties
General Function Involved in NADH dehydrogenase (ubiquinone) activity
Specific Function Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
GO Classification Not Available
Cellular Location
  1. Peripheral membrane protein
  2. Mitochondrion inner membrane
  3. Matrix side
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5q31
SNPs NDUFA2
Gene Sequence
>300 bp
ATGGCGGCGGCCGCAGCAAGTCGAGGAGTCGGGGCAAAGCTGGGCCTGCGTGAGATTCGC
ATCCACTTATGTCAGCGCTCGCCCGGCAGCCAGGGCGTCAGGGACTTCATTGAGAAACGC
TACGTGGAGCTGAAGAAGGCGAATCCCGACCTACCCATCCTAATCCGCGAATGCTCCGAT
GTGCAGCCCAAGCTCTGGGCCCGCTACGCATTTGGCCAAGAGACGAATGTCCCTTTGAAC
AACTTCAGTGCTGATCAGGTAACCAGAGCCCTGGAGAACGTTCTAAGTGGTAAAGCCTGA
Protein Properties
Number of Residues 99
Molecular Weight 10921.4
Theoretical pI 10.11
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
MAAAAASRGVGAKLGLREIRIHLCQRSPGSQGVRDFIEKRYVELKKANPDLPILIRECSD
VQPKLWARYAFGQETNVPLNNFSADQVTRALENVLSGKA
GenBank ID Protein 12539408
UniProtKB/Swiss-Prot ID O43678
UniProtKB/Swiss-Prot Entry Name NDUA2_HUMAN
PDB IDs
GenBank Gene ID AB054976
GeneCard ID NDUFA2
GenAtlas ID NDUFA2
HGNC ID HGNC:7685
References
General References Not Available