Identification |
HMDB Protein ID
| CDBP00154 |
Secondary Accession Numbers
| Not Available |
Name
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 |
Description
| Not Available |
Synonyms
|
- CI-B8
- Complex I-B8
- NADH-ubiquinone oxidoreductase B8 subunit
|
Gene Name
| NDUFA2 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in NADH dehydrogenase (ubiquinone) activity |
Specific Function
| Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone |
GO Classification
|
Not Available
|
Cellular Location
|
- Peripheral membrane protein
- Mitochondrion inner membrane
- Matrix side
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:5 |
Locus
| 5q31 |
SNPs
| NDUFA2 |
Gene Sequence
|
>300 bp
ATGGCGGCGGCCGCAGCAAGTCGAGGAGTCGGGGCAAAGCTGGGCCTGCGTGAGATTCGC
ATCCACTTATGTCAGCGCTCGCCCGGCAGCCAGGGCGTCAGGGACTTCATTGAGAAACGC
TACGTGGAGCTGAAGAAGGCGAATCCCGACCTACCCATCCTAATCCGCGAATGCTCCGAT
GTGCAGCCCAAGCTCTGGGCCCGCTACGCATTTGGCCAAGAGACGAATGTCCCTTTGAAC
AACTTCAGTGCTGATCAGGTAACCAGAGCCCTGGAGAACGTTCTAAGTGGTAAAGCCTGA
|
Protein Properties |
Number of Residues
| 99 |
Molecular Weight
| 10921.4 |
Theoretical pI
| 10.11 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2
MAAAAASRGVGAKLGLREIRIHLCQRSPGSQGVRDFIEKRYVELKKANPDLPILIRECSD
VQPKLWARYAFGQETNVPLNNFSADQVTRALENVLSGKA
|
External Links |
GenBank ID Protein
| 12539408 |
UniProtKB/Swiss-Prot ID
| O43678 |
UniProtKB/Swiss-Prot Entry Name
| NDUA2_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| AB054976 |
GeneCard ID
| NDUFA2 |
GenAtlas ID
| NDUFA2 |
HGNC ID
| HGNC:7685 |
References |
General References
| Not Available |