Showing Protein Deoxyhypusine synthase (CDBP00213)
| Identification | ||||||||||||||||||||
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| HMDB Protein ID | CDBP00213 | |||||||||||||||||||
| Secondary Accession Numbers | Not Available | |||||||||||||||||||
| Name | Deoxyhypusine synthase | |||||||||||||||||||
| Description | Not Available | |||||||||||||||||||
| Synonyms |
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| Gene Name | DHPS | |||||||||||||||||||
| Protein Type | Enzyme | |||||||||||||||||||
| Biological Properties | ||||||||||||||||||||
| General Function | Involved in peptidyl-lysine modification to hypusine | |||||||||||||||||||
| Specific Function | Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. | |||||||||||||||||||
| GO Classification |
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| Cellular Location | Not Available | |||||||||||||||||||
| Pathways |
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| Gene Properties | ||||||||||||||||||||
| Chromosome Location | 19 | |||||||||||||||||||
| Locus | 19p13.2 | |||||||||||||||||||
| SNPs | DHPS | |||||||||||||||||||
| Gene Sequence |
>1110 bp ATGGAAGGTTCCCTGGAACGGGAGGCGCCAGCGGGGGCGCTGGCCGCCGTGCTAAAGCAC AGCTCGACGTTGCCGCCCGAAAGCACCCAGGTCCGGGGCTACGACTTCAACCGCGGTGTG AATTACCGCGCACTGCTGGAGGCCTTCGGCACCACCGGCTTCCAAGCAACCAACTTCGGG CGCGCTGTACAGCAAGTCAATGCCATGATCGAGAAGAAGCTGGAACCACTGTCACAGGAT GAAGACCAGCACGCGGACCTGACCCAGAGCCGCCGCCCACTTACCAGCTGCACCATTTTC CTGGGATATACATCCAACCTCATCAGTTCAGGCATCCGTGAGACCATTCGCTACCTTGTG CAGCACAACATGGTGGACGTATTGGTGACCACAGCTGGCGGCGTGGAGGAAGACCTCATC AAGTGCCTGGCGCCCACATACTTGGGCGAGTTTAGCCTCAGGGGGAAGGAGCTCCGGGAG AACGGGATCAATAGGATCGGAAACCTGCTGGTGCCCAATGAGAATTACTGCAAGTTTGAG GACTGGCTGATGCCCATTCTGGACCAGATGGTGATGGAGCAGAACACAGAGGGTGTAAAG TGGACGCCTTCTAAGATGATCGCCCGGCTGGGCAAGGAGATCAACAACCCAGAGTCCGTG TATTACTGGGCCCAGAAGAACCACATCCCTGTGTTTAGTCCCGCACTTACAGACGGCTCG CTGGGCGACATGATCTTCTTCCATTCCTACAAGAACCCGGGCCTGGTCCTGGACATCGTT GAGGACCTGAGGCTCATCAACACACAGGCCATCTTTGCCAAGTGCACTGGGATGATCATT CTGGGCGGGGGCGTGGTCAAGCACCACATTGCCAATGCCAACCTCATGCGGAACGGGGCC GACTACGCTGTTTACATCAACACAGCCCAGGAGTTTGATGGCTCTGACTCAGGTGCCCGA CCAGACGAGGCTGTCTCCTGGGGCAAGATCCGGGTGGATGCACAGCCCGTCAAGGTCTAT GCTGACGCCTCCCTGGTCTTCCCCCTGCTTGTGGCTGAAACCTTTGCCCAGAAGATGGAT GCCTTCATGCATGAGAAGAACGAGGACTGA |
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| Protein Properties | ||||||||||||||||||||
| Number of Residues | 369 | |||||||||||||||||||
| Molecular Weight | 40970.28 | |||||||||||||||||||
| Theoretical pI | 5.36 | |||||||||||||||||||
| Pfam Domain Function |
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| Signals | Not Available | |||||||||||||||||||
| Transmembrane Regions | Not Available | |||||||||||||||||||
| Protein Sequence |
>Deoxyhypusine synthase MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFG RAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLV QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFE DWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGS LGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGA DYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMD AFMHEKNED |
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| External Links | ||||||||||||||||||||
| GenBank ID Protein | Not Available | |||||||||||||||||||
| UniProtKB/Swiss-Prot ID | P49366 | |||||||||||||||||||
| UniProtKB/Swiss-Prot Entry Name | DHYS_HUMAN | |||||||||||||||||||
| PDB IDs | ||||||||||||||||||||
| GenBank Gene ID | L39068 | |||||||||||||||||||
| GeneCard ID | DHPS | |||||||||||||||||||
| GenAtlas ID | DHPS | |||||||||||||||||||
| HGNC ID | HGNC:2869 | |||||||||||||||||||
| References | ||||||||||||||||||||
| General References | Not Available | |||||||||||||||||||