Identification |
HMDB Protein ID
| CDBP04083 |
Secondary Accession Numbers
| Not Available |
Name
| Poly [ADP-ribose] polymerase 8 |
Description
| Not Available |
Synonyms
|
- PARP-8
- ADP-ribosyltransferase diphtheria toxin-like 16
- ARTD16
|
Gene Name
| PARP8 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in NAD+ ADP-ribosyltransferase activity |
Specific Function
| Not Available |
GO Classification
|
Cellular Component |
intracellular |
Function |
catalytic activity |
transferase activity |
nad+ adp-ribosyltransferase activity |
transferase activity, transferring pentosyl groups |
transferase activity, transferring glycosyl groups |
Molecular Function |
NAD+ ADP-ribosyltransferase activity |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| 5 |
Locus
| 5q11.1 |
SNPs
| PARP8 |
Gene Sequence
|
>2565 bp
ATGGGGATGTGTTCAAGGCAAGAGCGAATTCAGAAGGATATCGACGTCGTGATCCAGAAG
TCCAGAGCTGAGAAGGACTGCCTGTTTGCAGATTTCAGATACTCTGACTCCACCTTTACT
TTTACCTACGTTGGCGGCCCCAGAAGTGTATCCTACTCAGTACATGTATCTGAAGATTAC
CCAGATAATACATATGTGTCAAGTTCAGAGAATGATGAAGATGTGCTAGTTACTACAGAG
CCAATACCAGTAATTTTTCATAGAATAGCAACAGAATTAAGAAAAACAAATGACATTAAC
TGTTGCTTATCCATAAAATCCAAATTACAAAAGGAAAATGGGGAGGAATCAAGACAGAAT
AGTACAGTGGAGGAAGATTCTGAAGGTGACAATGATTCCGAAGAATTTTATTACGGAGGG
CAGGTGAACTATGATGGGGAACTGCACAAGCACCCACAACTGGAAGCTGATTTGTCAGCA
GTTAGAGAGATATATGGGCCACATGCAGTTTCTCTCAGGGAATATGGAGCCATTGATGAT
GTAGATATTGATCTGCATATCGATGTTAGCTTTCTTGATGAGGAGATTGCTGTGGCTTGG
GAAGTAATTCGAACAGAACCTATAATTGTTCGACTACACTGTTCACTTACACAGTATTTA
AATGGCCCAGTGCCCACTGTTGATGTCTTTCAGATTTCCACAAAAGAGCGATTTGGATTG
GGACATCAGCTGAAAAAAATCATGCAGACATTTGTTACACAGCAGTGGAAACAGAGCAAA
GAAAAATCCAATTGCCTGCACAATAAAAAGTTGTCAGAGAAGAAAGTGAAGTCTCCCCTG
CATTTATTTTCTACTTTGCGCAGGTCGCCAAGTTATCCTCCCCCTGGTTGTGGCAAAAGC
AAATCCAAACTGAAATCTGAGCAGGACGGAATCTCCAAAACGCATAAGCTGCTGCGGAGG
ACTTGTTCCAGCACAGTCAAGACTGATGATGTGTGTGTCACAAAGTCACACAGGACCTTT
GGCCGCTCCTTGTCCAGCGATCCCAGGGCGGAGCAGGCTATGACAGCAATTAAATCGCAC
AAACTTTTGAACCGTCCTTGCCCTGCAGCTGTTAAGTCAGAGGAATGCCTAACTCTAAAG
TCGCATAGACTATTGACTCGATCTTGTTCTGGAGATCCACGATGTGAGCACAACACAAAC
TTGAAGCCCCATAAACTGTTAAGCAGGTCTTACTCTAGTAATCTCAGAATGGAAGAATTA
TATGGACTGAAAAATCACAAATTGCTCAGCAAGTCCTACTCCAGTGCCCCCAAGTCATCC
AAAACTGAGCTTTTCAAGGAACCTAACGCAGAGGGCAGGAGGCTCTCTCTTACCTCAGGG
CTTATTGGTATCCTAACACCATCTTCATCTTCATCTTCTCAGCTTGCTCCAAATGGTGCA
AAATGCATTCCAGTACGAGACCGTGGCTTCCTGGTGCAGACAATTGAGTTTGCTGAACAG
CGGATCCCTGTATTAAATGAATATTGTGTGGTTTGTGATGAGCCACATGTGTTTCAAAAT
GGCCCTATGCTTAGGCCTACCGTATGTGAACGGGAGCTGTGTGTGTTTGCTTTTCAAACC
CTGGGAGTAATGAATGAAGCTGCTGATGAAATAGCAACTGGAGCTCAGGTGGTAGATCTA
CTAGTATCCATGTGTAGGTCTGCGTTGGAATCTCCTAGAAAAGTTGTGATTTTCGAGCCA
TATCCTTCTGTGGTAGATCCTAATGATCCTCAGATGTTGGCCTTCAACCCCAGGAAAAAG
AACTATGATCGAGTAATGAAAGCACTGGATAGCATAACTTCTATCAGAGAAATGACACAA
GCACCATATCTGGAAATCAAGAAGCAAATGGATAAACAGGACCCCCTTGCTCATCCCTTA
CTGCAATGGGTTATATCAAGTAATAGATCACATATTGTGAAACTGCCAGTTAACAGGCAA
TTGAAGTTTATGCATACTCCACATCAGTTCCTTCTTCTCAGCAGTCCACCAGCCAAAGAA
TCCAATTTTAGAGCTGCTAAAAAACTCTTTGGAAGCACCTTTGCATTTCATGGCTCACAC
ATTGAAAACTGGCACTCCATCCTGAGGAATGGTCTGGTTGTTGCTTCTAATACACGATTG
CAGCTCCATGGTGCAATGTATGGAAGTGGAATCTATCTTAGTCCAATGTCAAGCATATCA
TTTGGTTACTCAGGGATGAACAAGAAACAGAAGGTGTCAGCCAAGGACGAGCCAGCTTCA
AGCAGTAAAAGCAGCAATACATCACAGTCACAGAAAAAAGGACAGCAATCCCAATTCCTG
CAAAGCCGTAACTTAAAATGCATAGCCTTATGTGAAGTGATCACCTCATCTGACCTGCAC
AAACATGGAGAGATATGGGTTGTCCCCAATACTGACCATGTCTGCACACGATTCTTTTTC
GTCTATGAAGACGGCCAAGTGGGAGATGCAAATATTAATACACAAGAAGGAGGCATTCAC
AAAGAGATCCTCCGAGTAATTGGTAATCAAACTGCTACTGGTTAA
|
Protein Properties |
Number of Residues
| 854 |
Molecular Weight
| 95870.105 |
Theoretical pI
| 8.279 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Poly [ADP-ribose] polymerase 8
MGMCSRQERIQKDIDVVIQKSRAEKDCLFADFRYSDSTFTFTYVGGPRSVSYSVHVSEDY
PDNTYVSSSENDEDVLVTTEPIPVIFHRIATELRKTNDINCCLSIKSKLQKENGEESRQN
STVEEDSEGDNDSEEFYYGGQVNYDGELHKHPQLEADLSAVREIYGPHAVSLREYGAIDD
VDIDLHIDVSFLDEEIAVAWEVIRTEPIIVRLHCSLTQYLNGPVPTVDVFQISTKERFGL
GHQLKKIMQTFVTQQWKQSKEKSNCLHNKKLSEKKVKSPLHLFSTLRRSPSYPPPGCGKS
KSKLKSEQDGISKTHKLLRRTCSSTVKTDDVCVTKSHRTFGRSLSSDPRAEQAMTAIKSH
KLLNRPCPAAVKSEECLTLKSHRLLTRSCSGDPRCEHNTNLKPHKLLSRSYSSNLRMEEL
YGLKNHKLLSKSYSSAPKSSKTELFKEPNAEGRRLSLTSGLIGILTPSSSSSSQLAPNGA
KCIPVRDRGFLVQTIEFAEQRIPVLNEYCVVCDEPHVFQNGPMLRPTVCERELCVFAFQT
LGVMNEAADEIATGAQVVDLLVSMCRSALESPRKVVIFEPYPSVVDPNDPQMLAFNPRKK
NYDRVMKALDSITSIREMTQAPYLEIKKQMDKQDPLAHPLLQWVISSNRSHIVKLPVNRQ
LKFMHTPHQFLLLSSPPAKESNFRAAKKLFGSTFAFHGSHIENWHSILRNGLVVASNTRL
QLHGAMYGSGIYLSPMSSISFGYSGMNKKQKVSAKDEPASSSKSSNTSQSQKKGQQSQFL
QSRNLKCIALCEVITSSDLHKHGEIWVVPNTDHVCTRFFFVYEDGQVGDANINTQEGGIH
KEILRVIGNQTATG
|
External Links |
GenBank ID Protein
| 295844829 |
UniProtKB/Swiss-Prot ID
| Q8N3A8 |
UniProtKB/Swiss-Prot Entry Name
| PARP8_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_001178055.1 |
GeneCard ID
| PARP8 |
GenAtlas ID
| PARP8 |
HGNC ID
| HGNC:26124 |
References |
General References
| Not Available |