| Identification |
|---|
| HMDB Protein ID
| CDBP00512 |
| Secondary Accession Numbers
| Not Available |
| Name
| D-beta-hydroxybutyrate dehydrogenase, mitochondrial |
| Description
| Not Available |
| Synonyms
|
- 3-hydroxybutyrate dehydrogenase
- BDH
|
| Gene Name
| BDH1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in oxidoreductase activity |
| Specific Function
| Not Available |
| GO Classification
|
| Biological Process |
| response to estradiol stimulus |
| response to cadmium ion |
| ketone body biosynthetic process |
| ketone body catabolic process |
| adipose tissue development |
| response to insulin stimulus |
| response to growth hormone stimulus |
| liver development |
| response to drug |
| response to ethanol |
| response to nutrient |
| response to starvation |
| brain development |
| response to corticosterone stimulus |
| response to toxin |
| cellular lipid metabolic process |
| Cellular Component |
| mitochondrial matrix |
| nucleus |
| mitochondrial inner membrane |
| Function |
| binding |
| catalytic activity |
| oxidoreductase activity |
| Molecular Function |
| 3-hydroxybutyrate dehydrogenase activity |
| phospholipid binding |
| nucleotide binding |
| Process |
| metabolic process |
| oxidation reduction |
|
| Cellular Location
|
- Mitochondrion matrix
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Ketone Body Metabolism |    |  | | Synthesis and degradation of ketone bodies | Not Available | | | Butanoate metabolism | Not Available |  | | Succinyl CoA: 3-ketoacid CoA transferase deficiency |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| 3 |
| Locus
| 3q29 |
| SNPs
| BDH1 |
| Gene Sequence
|
>1032 bp
ATGCTGGCCACCCGCCTCTCCAGACCCCTGTCACGGCTCCCAGGAAAAACCCTAAGTGCC
TGTGATAGAGAAAATGGAGCAAGACGCCCACTATTGCTTGGTTCTACTTCCTTTATCCCG
ATTGGCCGTCGGACTTATGCCAGTGCGGCGGAGCCGGTTGGCAGCAAAGCTGTCCTGGTC
ACAGGCTGTGACTCTGGATTTGGGTTCTCATTGGCCAAGCATCTGCATTCAAAAGGCTTC
CTTGTGTTTGCTGGCTGCTTGATGAAGGACAAAGGCCATGATGGGGTCAAGGAGCTGGAC
AGCCTAAACAGTGACCGATTGAGAACCGTCCAGCTCAATGTCTGCAGCAGCGAAGAGGTG
GAGAAAGTGGTGGAGATTGTCCGCTCGAGCCTGAAGGACCCTGAGAAAGGCATGTGGGGC
CTCGTTAACAATGCCGGCATCTCAACGTTCGGGGAGGTGGAGTTCACCAGCCTGGAGACC
TACAAGCAGGTGGCAGAAGTGAACCTTTGGGGCACAGTGCGGATGACGAAATCCTTTCTC
CCCCTCATCCGAAGGGCCAAAGGCCGCGTCGTCAATATCAGCAGCATGCTGGGCCGCATG
GCCAACCCGGCCCGCTCCCCGTACTGCATCACCAAGTTCGGGGTAGAGGCTTTCTCGGAC
TGCCTGCGCTATGAGATGTACCCCCTGGGCGTGAAGGTCAGCGTGGTGGAGCCCGGCAAC
TTCATCGCTGCCACCAGCCTTTACAGCCCTGAGAGCATTCAGGCCATCGCCAAGAAGATG
TGGGAGGAGCTGCCTGAGGTCGTGCGCAAGGACTACGGCAAGAAGTACTTTGATGAAAAG
ATCGCCAAGATGGAGACCTACTGCAGCAGTGGCTCCACAGACACGTCCCCTGTCATCGAT
GCTGTCACACACGCCCTGACCGCCACCACCCCCTACACCCGCTACCACCCCATGGACTAC
TACTGGTGGCTGCGAATGCAGATCATGACCCACTTGCCTGGAGCCATCTCCGACATGATC
TACATCCGCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 343 |
| Molecular Weight
| 38156.77 |
| Theoretical pI
| 8.949 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>D-beta-hydroxybutyrate dehydrogenase, mitochondrial
MLATRLSRPLSRLPGKTLSACDRENGARRPLLLGSTSFIPIGRRTYASAAEPVGSKAVLV
TGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEV
EKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFL
PLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGN
FIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVID
AVTHALTATTPYTRYHPMDYYWWLRMQIMTHLPGAISDMIYIR
|
| External Links |
|---|
| GenBank ID Protein
| 13543367 |
| UniProtKB/Swiss-Prot ID
| Q02338 |
| UniProtKB/Swiss-Prot Entry Name
| BDH_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC005844 |
| GeneCard ID
| BDH1 |
| GenAtlas ID
| BDH1 |
| HGNC ID
| HGNC:1027 |
| References |
|---|
| General References
| Not Available |