Identification
HMDB Protein ID CDBP00512
Secondary Accession Numbers Not Available
Name D-beta-hydroxybutyrate dehydrogenase, mitochondrial
Description Not Available
Synonyms
  1. 3-hydroxybutyrate dehydrogenase
  2. BDH
Gene Name BDH1
Protein Type Enzyme
Biological Properties
General Function Involved in oxidoreductase activity
Specific Function Not Available
GO Classification
Biological Process
response to estradiol stimulus
response to cadmium ion
ketone body biosynthetic process
ketone body catabolic process
adipose tissue development
response to insulin stimulus
response to growth hormone stimulus
liver development
response to drug
response to ethanol
response to nutrient
response to starvation
brain development
response to corticosterone stimulus
response to toxin
cellular lipid metabolic process
Cellular Component
mitochondrial matrix
nucleus
mitochondrial inner membrane
Function
binding
catalytic activity
oxidoreductase activity
Molecular Function
3-hydroxybutyrate dehydrogenase activity
phospholipid binding
nucleotide binding
Process
metabolic process
oxidation reduction
Cellular Location
  1. Mitochondrion matrix
Pathways
Gene Properties
Chromosome Location 3
Locus 3q29
SNPs BDH1
Gene Sequence
>1032 bp
ATGCTGGCCACCCGCCTCTCCAGACCCCTGTCACGGCTCCCAGGAAAAACCCTAAGTGCC
TGTGATAGAGAAAATGGAGCAAGACGCCCACTATTGCTTGGTTCTACTTCCTTTATCCCG
ATTGGCCGTCGGACTTATGCCAGTGCGGCGGAGCCGGTTGGCAGCAAAGCTGTCCTGGTC
ACAGGCTGTGACTCTGGATTTGGGTTCTCATTGGCCAAGCATCTGCATTCAAAAGGCTTC
CTTGTGTTTGCTGGCTGCTTGATGAAGGACAAAGGCCATGATGGGGTCAAGGAGCTGGAC
AGCCTAAACAGTGACCGATTGAGAACCGTCCAGCTCAATGTCTGCAGCAGCGAAGAGGTG
GAGAAAGTGGTGGAGATTGTCCGCTCGAGCCTGAAGGACCCTGAGAAAGGCATGTGGGGC
CTCGTTAACAATGCCGGCATCTCAACGTTCGGGGAGGTGGAGTTCACCAGCCTGGAGACC
TACAAGCAGGTGGCAGAAGTGAACCTTTGGGGCACAGTGCGGATGACGAAATCCTTTCTC
CCCCTCATCCGAAGGGCCAAAGGCCGCGTCGTCAATATCAGCAGCATGCTGGGCCGCATG
GCCAACCCGGCCCGCTCCCCGTACTGCATCACCAAGTTCGGGGTAGAGGCTTTCTCGGAC
TGCCTGCGCTATGAGATGTACCCCCTGGGCGTGAAGGTCAGCGTGGTGGAGCCCGGCAAC
TTCATCGCTGCCACCAGCCTTTACAGCCCTGAGAGCATTCAGGCCATCGCCAAGAAGATG
TGGGAGGAGCTGCCTGAGGTCGTGCGCAAGGACTACGGCAAGAAGTACTTTGATGAAAAG
ATCGCCAAGATGGAGACCTACTGCAGCAGTGGCTCCACAGACACGTCCCCTGTCATCGAT
GCTGTCACACACGCCCTGACCGCCACCACCCCCTACACCCGCTACCACCCCATGGACTAC
TACTGGTGGCTGCGAATGCAGATCATGACCCACTTGCCTGGAGCCATCTCCGACATGATC
TACATCCGCTGA
Protein Properties
Number of Residues 343
Molecular Weight 38156.77
Theoretical pI 8.949
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>D-beta-hydroxybutyrate dehydrogenase, mitochondrial
MLATRLSRPLSRLPGKTLSACDRENGARRPLLLGSTSFIPIGRRTYASAAEPVGSKAVLV
TGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEV
EKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFL
PLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGN
FIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVID
AVTHALTATTPYTRYHPMDYYWWLRMQIMTHLPGAISDMIYIR
GenBank ID Protein 13543367
UniProtKB/Swiss-Prot ID Q02338
UniProtKB/Swiss-Prot Entry Name BDH_HUMAN
PDB IDs Not Available
GenBank Gene ID BC005844
GeneCard ID BDH1
GenAtlas ID BDH1
HGNC ID HGNC:1027
References
General References Not Available