Showing Protein NADH dehydrogenase [ubiquinone] 1 subunit C2 (CDBP00165)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 5 compounds
Identification
HMDB Protein ID CDBP00165
Secondary Accession Numbers Not Available
Name NADH dehydrogenase [ubiquinone] 1 subunit C2
Description Not Available
Synonyms
  1. CI-B14.5b
  2. Complex I-B14.5b
  3. HLC-1
  4. Human lung cancer oncogene 1 protein
  5. NADH-ubiquinone oxidoreductase subunit B14.5b
Gene Name NDUFC2
Protein Type Enzyme
Biological Properties
General Function Involved in NADH dehydrogenase (ubiquinone) activity
Specific Function Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
GO Classification
Component
organelle inner membrane
mitochondrial inner membrane
membrane
cell part
organelle membrane
Function
catalytic activity
nadh dehydrogenase activity
nadh dehydrogenase (quinone) activity
nadh dehydrogenase (ubiquinone) activity
oxidoreductase activity
oxidoreductase activity, acting on nadh or nadph
Process
metabolic process
generation of precursor metabolites and energy
electron transport chain
respiratory electron transport chain
cellular metabolic process
mitochondrial electron transport, nadh to ubiquinone
Cellular Location
  1. Single-pass membrane protein
  2. Mitochondrion inner membrane
  3. Matrix side
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 11q14.1
SNPs NDUFC2
Gene Sequence 
>360 bp
ATGATCGCACGGCGGAACCCAGAACCCTTACGGTTTCTGCCGGATGAGGCCCGGAGCCTG
CCCCCGCCCAAGCTGACCGACCCGCGGCTCCTCTACATCGGCTTCTTGGGCTACTGCTCC
GGCCTGATTGATAACCTGATCCGGCGGAGGCCGATCGCGACGGCTGGTTTGCATCGCCAG
CTTCTATATATTACGGCCTTTTTTTTTGCTGGATATTATCTTGTAAAACGTGAAGACTAC
CTGTATGCTGTGAGGGACCGTGAAATGTTTGGATATATGAAATTACATCCAGAGGATTTT
CCTGAAGAAGATAAGAAAACATATGGTGAAATTTTTGAAAAATTCCATCCAATACGTTGA
Protein Properties
Number of Residues 119
Molecular Weight 14187.3
Theoretical pI 9.27
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["56-75"]
Protein Sequence 
>NADH dehydrogenase [ubiquinone] 1 subunit C2
MIARRNPEPLRFLPDEARSLPPPKLTDPRLLYIGFLGYCSGLIDNLIRRRPIATAGLHRQ
LLYITAFFFAGYYLVKREDYLYAVRDREMFGYMKLHPEDFPEEDKKTYGEIFEKFHPIR
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID O95298
UniProtKB/Swiss-Prot Entry Name NDUC2_HUMAN
PDB IDs Not Available
GenBank Gene ID AF087659
GeneCard ID NDUFC2
GenAtlas ID NDUFC2
HGNC ID HGNC:7706
References
General References Not Available