Identification |
HMDB Protein ID
| CDBP02218 |
Secondary Accession Numbers
| Not Available |
Name
| Glycine cleavage system H protein, mitochondrial |
Description
| Not Available |
Synonyms
|
Not Available
|
Gene Name
| GCSH |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in glycine catabolic process |
Specific Function
| The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
|
GO Classification
|
Biological Process |
glycine catabolic process |
glycine decarboxylation via glycine cleavage system |
Cellular Component |
mitochondrion |
glycine cleavage complex |
Component |
mitochondrion |
macromolecular complex |
protein complex |
organelle |
membrane-bounded organelle |
intracellular membrane-bounded organelle |
glycine cleavage complex |
Molecular Function |
aminomethyltransferase activity |
Process |
serine family amino acid metabolic process |
glycine metabolic process |
glycine catabolic process |
cellular amino acid and derivative metabolic process |
cellular amino acid metabolic process |
metabolic process |
cellular metabolic process |
glycine decarboxylation via glycine cleavage system |
|
Cellular Location
|
- Mitochondrion
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Glyoxylate and dicarboxylate metabolism | Not Available | | Ammonia Recycling | | |
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| GCSH |
Gene Sequence
|
>522 bp
ATGGCGCTGCGAGTGGTGCGGAGCGTGCGGGCCCTGCTCTGCACCCTGCGCGCGGTCCCG
TTACCCGCCGCGCCCTGCCCGCCGAGGCCCTGGCAGCTGGGGGTGGGCGCCGTCCGTACG
CTGCGCACTGGACCCGCTCTGCTCTCGGTGCGTAAATTCACAGAGAAACACGAATGGGTA
ACAACAGAAAATGGCATTGGAACAGTGGGAATCAGCAATTTTGCACAGGAAGCGTTGGGA
GATGTTGTTTATTGTAGTCTCCCTGAAGTTGGGACAAAATTGAACAAACAAGATGAGTTT
GGTGCTTTGGAAAGTGTGAAAGCTGCTAGTGAACTCTATTCTCCTTTATCAGGAGAAGTA
ACTGAAATTAATGAAGCTCTTGCAGAAAATCCAGGACTTGTAAACAAATCTTGTTATGAA
GATGGTTGGCTGATCAAGATGACACTGAGTAACCCTTCAGAACTAGATGAACTTATGAGT
GAAGAAGCATATGAGAAATACATAAAATCTATTGAGGAGTGA
|
Protein Properties |
Number of Residues
| 173 |
Molecular Weight
| Not Available |
Theoretical pI
| Not Available |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Glycine cleavage system H protein, mitochondrial
MALRVVRSVRALLCTLRAVPLPAAPCPPRPWQLGVGAVRTLRTGPALLSVRKFTEKHEWV
TTENGIGTVGISNFAQEALGDVVYCSLPEVGTKLNKQDEFGALESVKAASELYSPLSGEV
TEINEALAENPGLVNKSCYEDGWLIKMTLSNPSELDELMSEEAYEKYIKSIEE
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| P23434 |
UniProtKB/Swiss-Prot Entry Name
| GCSH_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| M69175 |
GeneCard ID
| GCSH |
GenAtlas ID
| GCSH |
HGNC ID
| HGNC:4208 |
References |
General References
| Not Available |