Identification |
HMDB Protein ID
| CDBP00122 |
Secondary Accession Numbers
| Not Available |
Name
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 |
Description
| Not Available |
Synonyms
|
- CI-MWFE
- Complex I-MWFE
- NADH-ubiquinone oxidoreductase MWFE subunit
|
Gene Name
| NDUFA1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in NADH dehydrogenase (ubiquinone) activity |
Specific Function
| Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone |
GO Classification
|
Not Available
|
Cellular Location
|
- Single-pass membrane protein
- Mitochondrion inner membrane
- Matrix side
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Mitochondrial Electron Transport Chain | | |
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| NDUFA1 |
Gene Sequence
|
>213 bp
ATGTGGTTCGAGATTCTCCCCGGACTCTCCGTCATGGGCGTGTGCTTGTTGATTCCAGGA
CTGGCTACTGCGTACATCCACAGGTTCACTAACGGGGGCAAGGAAAAAAGGGTTGCTCAT
TTTGGGTATCACTGGAGTCTGATGGAAAGAGATAGGCGCATCTCTGGAGTTGATCGTTAC
TATGTGTCAAAGGGTTTGGAGAACATTGATTAA
|
Protein Properties |
Number of Residues
| 70 |
Molecular Weight
| 8072.3 |
Theoretical pI
| 9.12 |
Pfam Domain Function
|
Not Available |
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
MWFEILPGLSVMGVCLLIPGLATAYIHRFTNGGKEKRVAHFGYHWSLMERDRRISGVDRY
YVSKGLENID
|
External Links |
GenBank ID Protein
| 12653011 |
UniProtKB/Swiss-Prot ID
| O15239 |
UniProtKB/Swiss-Prot Entry Name
| NDUA1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| BC000266 |
GeneCard ID
| NDUFA1 |
GenAtlas ID
| NDUFA1 |
HGNC ID
| HGNC:7683 |
References |
General References
| Not Available |