Identification
HMDB Protein ID CDBP00122
Secondary Accession Numbers Not Available
Name NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
Description Not Available
Synonyms
  1. CI-MWFE
  2. Complex I-MWFE
  3. NADH-ubiquinone oxidoreductase MWFE subunit
Gene Name NDUFA1
Protein Type Enzyme
Biological Properties
General Function Involved in NADH dehydrogenase (ubiquinone) activity
Specific Function Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
GO Classification Not Available
Cellular Location
  1. Single-pass membrane protein
  2. Mitochondrion inner membrane
  3. Matrix side
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs NDUFA1
Gene Sequence
>213 bp
ATGTGGTTCGAGATTCTCCCCGGACTCTCCGTCATGGGCGTGTGCTTGTTGATTCCAGGA
CTGGCTACTGCGTACATCCACAGGTTCACTAACGGGGGCAAGGAAAAAAGGGTTGCTCAT
TTTGGGTATCACTGGAGTCTGATGGAAAGAGATAGGCGCATCTCTGGAGTTGATCGTTAC
TATGTGTCAAAGGGTTTGGAGAACATTGATTAA
Protein Properties
Number of Residues 70
Molecular Weight 8072.3
Theoretical pI 9.12
Pfam Domain Function Not Available
Signals
  • ["None"]
Transmembrane Regions
  • ["1-21"]
Protein Sequence
>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
MWFEILPGLSVMGVCLLIPGLATAYIHRFTNGGKEKRVAHFGYHWSLMERDRRISGVDRY
YVSKGLENID
GenBank ID Protein 12653011
UniProtKB/Swiss-Prot ID O15239
UniProtKB/Swiss-Prot Entry Name NDUA1_HUMAN
PDB IDs Not Available
GenBank Gene ID BC000266
GeneCard ID NDUFA1
GenAtlas ID NDUFA1
HGNC ID HGNC:7683
References
General References Not Available