Identification
HMDB Protein ID CDBP00849
Secondary Accession Numbers Not Available
Name Ecto-ADP-ribosyltransferase 3
Description Not Available
Synonyms
  1. Mono(ADP-ribosyl)transferase 3
  2. NAD(P)(+)--arginine ADP-ribosyltransferase 3
  3. ADP-ribosyltransferase C2 and C3 toxin-like 3
  4. ARTC3
Gene Name ART3
Protein Type Enzyme
Biological Properties
General Function Involved in NAD(P)+-protein-arginine ADP-ribosyltransferase activity
Specific Function Not Available
GO Classification
Biological Process
protein ADP-ribosylation
Cellular Component
anchored to membrane
integral to plasma membrane
Function
catalytic activity
transferase activity
nad(p)+-protein-arginine adp-ribosyltransferase activity
transferase activity, transferring pentosyl groups
transferase activity, transferring glycosyl groups
Molecular Function
NAD(P)+-protein-arginine ADP-ribosyltransferase activity
NAD+ ADP-ribosyltransferase activity
Process
macromolecule metabolic process
protein amino acid adp-ribosylation
post-translational protein modification
macromolecule modification
protein modification process
metabolic process
Cellular Location
  1. Cell membrane
  2. Lipid-anchor
  3. GPI-anchor
Pathways
Gene Properties
Chromosome Location 4
Locus 4p15.1-p14
SNPs ART3
Gene Sequence
>1170 bp
ATGAAGACGGGACATTTTGAAATAGTCACCATGCTGCTGGCAACCATGATTCTAGTGGAC
ATTTTCCAGGTGAAGGCTGAAGTGTTAGACATGGCAGATAATGCATTTGATGATGAATAC
CTGAAATGTACGGACAGGATGGAAATTAAATACGTTCCCCAACTGCTAAAGGAGGAAAAA
GCAAGCCACCAGCAATTAGATACTGTGTGGGAAAATGCAAAAGCCAAATGGGCAGCCCGA
AAGACTCAAATCTTTCTCCCTATGAATTTTAAGGATAACCATGGAATAGCCCTGATGGCA
TATATTTCCGAAGCTCAAGAGCAAACTCCCTTTTACCATCTGTTCAGTGAAGCTGTGAAG
ATGGCTGGCCAATCTCGAGAAGATTATATCTATGGCTTCCAGTTCAAAGCTTTCCACTTT
TACCTCACAAGAGCCCTGCAGTTGCTGAGAAAACCTTGTGAGGCCAGTTCCAAAACTGTG
GTATATAGAACAAGCCAGGGCACTTCATTTACATTTGGAGGGCTAAACCAAGCCAGGTTT
GGCCATTTTACCTTGGCATATTCAGCCAAACCTCAGGCTGCTAATGACCAGCTCACTGTG
TTATCCATCTACACATGCCTTGGAGTTGACATTGAAAATTTTCTTGATAAAGAAAGTGAA
AGAATTACTTTAATACCTCTGAATGAGGTTTTTCAAGTGTCACAGGAGGGGGCTGGCAAT
AACCTTATCCTTCAAAGCATAAACAAGACCTGCAGCCATTATGAGTGTGCATTTCTAGGT
GGACTAAAAACCGAAAACTGTATTGAGAACCTAGAATATTTTCAACCCATCTATGTCTAC
AACCCTGGTGAGAAAAACCAGAAGCTTGAAGACCATAGTGAGAAAAACTGGAAGCTTGAA
GACCATGGTGAGAAAAACCAGAAGCTTGAAGACCATGGTGTGAAAATCCTTGAACCCACC
CAAATACCTGGAATGAAAATTCCAGAACCTTTTCCACTACCTGAAGATAAAAGTCAAGGA
AATATCAACAATCCTACTCCAGGTCCAGTTCCTGTTCCAGGTCCCAAAAGCCATCCTTCT
GCATCCTTGGGCAAACTGCTGCTTCCACAGTTTGGGATGGTCATCATTTTAATCAGTGTT
TCTGCTATAAATCTCTTTGTTGCTCTGTAG
Protein Properties
Number of Residues 389
Molecular Weight 43922.97
Theoretical pI 6.062
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Ecto-ADP-ribosyltransferase 3
MKTGHFEIVTMLLATMILVDIFQVKAEVLDMADNAFDDEYLKCTDRMEIKYVPQLLKEEK
ASHQQLDTVWENAKAKWAARKTQIFLPMNFKDNHGIALMAYISEAQEQTPFYHLFSEAVK
MAGQSREDYIYGFQFKAFHFYLTRALQLLRKPCEASSKTVVYRTSQGTSFTFGGLNQARF
GHFTLAYSAKPQAANDQLTVLSIYTCLGVDIENFLDKESERITLIPLNEVFQVSQEGAGN
NLILQSINKTCSHYECAFLGGLKTENCIENLEYFQPIYVYNPGEKNQKLEDHSEKNWKLE
DHGEKNQKLEDHGVKILEPTQIPGMKIPEPFPLPEDKSQGNINNPTPGPVPVPGPKSHPS
ASSGKLLLPQFGMVIILISVSAINLFVAL
GenBank ID Protein 14250010
UniProtKB/Swiss-Prot ID Q13508
UniProtKB/Swiss-Prot Entry Name NAR3_HUMAN
PDB IDs Not Available
GenBank Gene ID BC008397
GeneCard ID ART3
GenAtlas ID ART3
HGNC ID HGNC:725
References
General References Not Available