| Identification |
|---|
| HMDB Protein ID
| CDBP00125 |
| Secondary Accession Numbers
| Not Available |
| Name
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 |
| Description
| Not Available |
| Synonyms
|
- CI-19kD
- CI-PGIV
- Complex I-19kD
- Complex I-PGIV
- NADH-ubiquinone oxidoreductase 19 kDa subunit
- SubName: cDNA, FLJ94833, Homo sapiens NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa (NDUFA8), mRNA
|
| Gene Name
| NDUFA8 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in NADH dehydrogenase (ubiquinone) activity |
| Specific Function
| Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Mitochondrion
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:9 |
| Locus
| 9q33.2 |
| SNPs
| NDUFA8 |
| Gene Sequence
|
>519 bp
ATGCCGGGGATAGTGGAGCTGCCCACTCTAGAGGAGCTGAAAGTAGATGAGGTGAAAATT
AGTTCTGCTGTGCTTAAAGCTGCGGCCCATCACTATGGAGCTCAATGTGATAAGCCCAAC
AAGGAATTTATGCTCTGCCGCTGGGAAGAGAAAGATCCGAGGCGGTGTTTAGAGGAAGGC
AAACTGGTCAACAAGTGTGCTTTGGACTTCTTTAGGCAGATAAAACGTCACTGTGCAGAG
CCTTTTACAGAATATTGGACTTGCATTGATTATACTGGCCAGCAGTTATTTCGTCACTGT
CGCAAACAGCAGGCAAAGTTTGACGAGTGTGTGCTGGACAAACTGGGCTGGGTGCGGCCT
GACCTGGGAGAACTGTCAAAGGTCACCAAAGTGAAAACAGATCGACCTTTACCGGAGAAT
CCCTATCACTCAAGACCAAGACCGGATCCCAGCCCTGAGATCGAGGGAGATCTGCAGCCT
GCCACACATGGCAGCCGCTTTTATTTCTGGACCAAGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 172 |
| Molecular Weight
| 20104.9 |
| Theoretical pI
| 7.74 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8
MPGIVELPTLEELKVDEVKISSAVLKAAAHHYGAQCDKPNKEFMLCRWEEKDPRRCLEEG
KLVNKCALDFFRQIKRHCAEPFTEYWTCIDYTGQQLFRHCRKQQAKFDECVLDKLGWVRP
DLGELSKVTKVKTDRPLPENPYHSRPRPDPSPEIEGDLQPATHGSRFYFWTK
|
| External Links |
|---|
| GenBank ID Protein
| 5326825 |
| UniProtKB/Swiss-Prot ID
| P51970 |
| UniProtKB/Swiss-Prot Entry Name
| NDUA8_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF044953 |
| GeneCard ID
| NDUFA8 |
| GenAtlas ID
| NDUFA8 |
| HGNC ID
| HGNC:7692 |
| References |
|---|
| General References
| Not Available |