| Identification |
|---|
| HMDB Protein ID
| CDBP04084 |
| Secondary Accession Numbers
| Not Available |
| Name
| Poly [ADP-ribose] polymerase 9 |
| Description
| Not Available |
| Synonyms
|
- B aggressive lymphoma protein
- PARP-9
- ADP-ribosyltransferase diphtheria toxin-like 9
- ARTD9
|
| Gene Name
| PARP9 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in NAD+ ADP-ribosyltransferase activity |
| Specific Function
| Involved in inducing the expression of IFN-gamma-responsive genes.
|
| GO Classification
|
| Biological Process |
| cell migration |
| regulation of response to interferon-gamma |
| Cellular Component |
| cytosol |
| cytoplasm |
| nucleus |
| Function |
| catalytic activity |
| transferase activity |
| nad+ adp-ribosyltransferase activity |
| transferase activity, transferring pentosyl groups |
| transferase activity, transferring glycosyl groups |
| Molecular Function |
| NAD+ ADP-ribosyltransferase activity |
|
| Cellular Location
|
- Nucleus
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 3 |
| Locus
| 3q21 |
| SNPs
| PARP9 |
| Gene Sequence
|
>2565 bp
ATGGACTTTTCCATGGTGGCCGGAGCAGCAGCTTACAATGAAAAATCAGGTAGGATTACC
TCGCTCTCACTCTTGTTTCAGAAAGTCTTTGCTCAGATCTTTCCTCAGTGGAGAAAGGGG
AATACAGAAGAATGTCTCCCCTACAAGTGCTCAGAGACTGGTGCTCTTGGAGAAAACTAT
AGTTGGCAAATTCCCATTAACCACAATGACTTCAAAATTTTAAAAAATAATGAGCGTCAG
CTGTGTGAAGTCCTCCAGAATAAGTTTGGCTGTATCTCTACCCTGGTCTCTCCAGTTCAG
GAAGGCAACAGCAAATCTCTGCAAGTGTTCAGAAAAATGCTGACTCCTAGGATAGAGTTA
TCAGTCTGGAAAGATGACCTCACCACACATGCTGTTGATGCTGTGGTGAATGCAGCCAAT
GAAGATCTTCTGCATGGGGGAGGCCTGGCCCTGGCCCTGGTAAAAGCTGGTGGATTTGAA
ATCCAAGAAGAGAGCAAACAGTTTGTTGCCAGATATGGTAAAGTGTCAGCTGGTGAGATA
GCTGTCACGGGAGCAGGGAGGCTTCCCTGCAAACAGATCATCCATGCTGTTGGGCCTCGG
TGGATGGAATGGGATAAACAGGGATGTACTGGAAAGCTGCAGAGGGCCATTGTAAGTATT
CTGAATTATGTCATCTATAAAAATACTCACATTAAGACAGTAGCAATTCCAGCCTTGAGC
TCTGGGATTTTTCAGTTCCCTCTGAATTTGTGTACAAAGACTATTGTAGAGACTATCCGG
GTTAGTTTGCAAGGGAAGCCAATGATGAGTAATTTGAAAGAAATTCACCTGGTGAGCAAT
GAGGACCCTACTGTTGCTGCCTTTAAAGCTGCTTCAGAATTCATCCTAGGGAAGAGTGAG
CTGGGACAAGAAACCACCCCTTCTTTCAATGCAATGGTCGTGAACAACCTGACCCTCCAG
ATTGTCCAGGGCCACATTGAATGGCAGACGGCAGATGTAATTGTTAATTCTGTAAACCCA
CATGATATTACAGTTGGACCTGTGGCAAAGTCAATTCTACAACAAGCAGGAGTTGAAATG
AAATCGGAATTTCTTGCCACAAAGGCTAAACAGTTTCAACGGTCCCAGTTGGTACTGGTC
ACAAAAGGATTTAACTTGTTCTGTAAATATATATACCATGTACTGTGGCATTCAGAATTT
CCTAAACCTCAGATATTAAAACATGCAATGAAGGAGTGTTTGGAAAAATGCATTGAGCAA
AATATAACTTCCATTTCCTTTCCTGCCCTTGGGACTGGAAACATGGAAATAAAGAAGGAA
ACAGCAGCAGAGATTTTGTTTGATGAAGTTTTAACATTTGCCAAAGACCATGTAAAACAC
CAGTTAACTGTAAAATTTGTGATCTTTCCAACAGATTTGGAGATATATAAGGCTTTCAGT
TCTGAAATGGCAAAGAGGTCCAAGATGCTGAGTTTGAACAATTACAGTGTCCCCCAGTCA
ACCAGAGAGGAGAAAAGAGAAAATGGGCTTGAAGCTAGATCTCCTGCCATCAATCTGATG
GGATTCAACGTGGAAGAGATGTGTGAGGCCCACGCATGGATCCAAAGAATCCTGAGTCTC
CAGAACCACCACATCATTGAGAATAATCATATTCTGTACCTTGGGAGAAAGGAACATGAC
ATTTTGTCTCAGCTTCAGAAAACTTCAAGTGTCTCCATCACAGAAATTATCAGCCCAGGA
AGGACAGAGTTAGAGATTGAAGGAGCCCGGGCTGACCTCATTGAGGTGGTTATGAACATT
GAAGATATGCTTTGTAAAGTACAGGAGGAAATGGCAAGGAAAAAGGAGCGAGGCCTTTGG
CGCTCGTTAGGACAGTGGACTATTCAGCAACAAAAAACCCAAGACGAAATGAAAGAAAAT
ATCATATTTCTGAAATGTCCTGTGCCTCCAACTCAAGAGCTTCTAGATCAAAAGAAACAG
TTTGAAAAATGTGGTTTGCAGGTTCTAAAGGTGGAGAAGATAGACAATGAGGTCCTTATG
GCTGCCTTTCAAAGAAAGAAGAAAATGATGGAAGAAAAACTGCACAGGCAACCTGTGAGC
CATAGGCTGTTTCAGCAAGTCCCATACCAGTTCTGCAATGTGGTATGCAGAGTTGGCTTT
CAAAGAATGTACTCGACACCTTGCGATCCAAAATACGGAGCTGGCATATACTTCACCAAG
AACCTCAAAAACCTGGCAGAGAAGGCCAAGAAAATCTCTGCTGCAGATAAGCTGATCTAT
GTGTTTGAGGCTGAAGTACTCACAGGCTTCTTCTGCCAGGGACATCCGTTAAATATTGTT
CCCCCACCACTGAGTCCTGGAGCTATAGATGGTCATGACAGTGTGGTTGACAATGTCTCC
AGCCCTGAAACCTTTGTTATTTTTAGTGGCATGCAGGCTATACCTCAGTATTTGTGGACA
TGCACCCAGGAATATGTACAGTCACAAGATTACTCATCAGGACCAATGAGACCCTTTGCA
CAGCATCCTTGGAGGGGATTCGCAAGTGGCAGCCCTGTTGATTAA
|
| Protein Properties |
|---|
| Number of Residues
| 854 |
| Molecular Weight
| 96342.655 |
| Theoretical pI
| 7.916 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Poly [ADP-ribose] polymerase 9
MDFSMVAGAAAYNEKSGRITSLSLLFQKVFAQIFPQWRKGNTEECLPYKCSETGALGENY
SWQIPINHNDFKILKNNERQLCEVLQNKFGCISTLVSPVQEGNSKSLQVFRKMLTPRIEL
SVWKDDLTTHAVDAVVNAANEDLLHGGGLALALVKAGGFEIQEESKQFVARYGKVSAGEI
AVTGAGRLPCKQIIHAVGPRWMEWDKQGCTGKLQRAIVSILNYVIYKNTHIKTVAIPALS
SGIFQFPLNLCTKTIVETIRVSLQGKPMMSNLKEIHLVSNEDPTVAAFKAASEFILGKSE
LGQETTPSFNAMVVNNLTLQIVQGHIEWQTADVIVNSVNPHDITVGPVAKSILQQAGVEM
KSEFLATKAKQFQRSQLVLVTKGFNLFCKYIYHVLWHSEFPKPQILKHAMKECLEKCIEQ
NITSISFPALGTGNMEIKKETAAEILFDEVLTFAKDHVKHQLTVKFVIFPTDLEIYKAFS
SEMAKRSKMLSLNNYSVPQSTREEKRENGLEARSPAINLMGFNVEEMYEAHAWIQRILSL
QNHHIIENNHILYLGRKEHDILSQLQKTSSVSITEIISPGRTELEIEGARADLIEVVMNI
EDMLCKVQEEMARKKERGLWRSLGQWTIQQQKTQDEMKENIIFLKCPVPPTQELLDQKKQ
FEKCGLQVLKVEKIDNEVLMAAFQRKKKMMEEKLHRQPVSHRLFQQVPYQFCNVVCRVGF
QRMYSTPCDPKYGAGIYFTKNLKNLAEKAKKISAADKLIYVFEAEVLTGFFCQGHPLNIV
PPPLSPGAIDGHDSVVDNVSSPETFVIFSGMQAIPQYLWTCTQEYVQSQDYSSGPMRPFA
QHPWRGFASGSPVD
|
| External Links |
|---|
| GenBank ID Protein
| 12751139 |
| UniProtKB/Swiss-Prot ID
| Q8IXQ6 |
| UniProtKB/Swiss-Prot Entry Name
| PARP9_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF307338 |
| GeneCard ID
| PARP9 |
| GenAtlas ID
| PARP9 |
| HGNC ID
| HGNC:24118 |
| References |
|---|
| General References
| Not Available |