4085 CDBP04084 Poly [ADP-ribose] polymerase 9 Q8IXQ6 PARP9_HUMAN true false Enzyme Homo_sapiens PARP9 854 96342.655 7.916 Involved in NAD+ ADP-ribosyltransferase activity Involved in inducing the expression of IFN-gamma-responsive genes. AF307338 12751139 PARP9 3 3q21 PARP9 HGNC:24118 true hsa:83666 NP_001139574.1:NM_001146102.1;NP_001139575.1:NM_001146103.1;NP_001139576.1:NM_001146104.1;NP_001139577.1:NM_001146105.1;NP_113646.2:NM_031458.2 Expressed in lymphocyte-rich tissues, spleen, lymph nodes, peripheral blood lymphocytes and colonic mucosa. Also expressed in nonhematopoietic tissues such as heart and skeletal muscle. Isoform 2 is the predominant form. Most abundantly expressed in lymphomas with a brisk host inflammatory response. In diffuse large B-cell lymphomas tumors, expressed specifically by malignant B-cells. Interacts with DTX3L 2020-06-12T23:07:21Z 2020-07-28T02:29:24Z 0 0 0