Cannabis Compound Database: Showing Protein Biliverdin reductase A (CDBP00664)

Identification Biological properties Gene properties Protein properties External links References XML Show 7 compounds

Identification

HMDB Protein ID

CDBP00664

Secondary Accession Numbers

Not Available

Name

Biliverdin reductase A

Description

Not Available

Synonyms

BVR A
Biliverdin-IX alpha-reductase

Gene Name

BLVRA

Protein Type

Enzyme

Biological Properties

General Function

Involved in biliverdin reductase activity

Specific Function

Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.

GO Classification

Biological Process
small molecule metabolic process
heme catabolic process
Cellular Component
cytosol
Component
cell part
intracellular part
cytoplasm
Function
metal ion binding
binding
catalytic activity
transition metal ion binding
zinc ion binding
oxidoreductase activity, acting on the ch-ch group of donors, nad or nadp as acceptor
biliverdin reductase activity
oxidoreductase activity
oxidoreductase activity, acting on the ch-ch group of donors
ion binding
cation binding
Molecular Function
metal ion binding
biliverdin reductase activity
zinc ion binding
nucleotide binding
Process
porphyrin catabolic process
heme catabolic process
oxidation reduction
metabolic process
nitrogen compound metabolic process
tetrapyrrole metabolic process
porphyrin metabolic process

Cellular Location

Cytoplasm

Pathways

Name	SMPDB/Pathwhiz	KEGG
Porphyrin Metabolism
protoheme degradation	Not Available	Not Available
Porphyrin and chlorophyll metabolism	Not Available
Acute Intermittent Porphyria		Not Available
Porphyria Variegata (PV)		Not Available

Gene Properties

Chromosome Location

Locus

7p13

SNPs

BLVRA

Gene Sequence

>891 bp
ATGAATGCAGAGCCCGAGAGGAAGTTTGGCGTGGTGGTGGTTGGTGTTGGCCGAGCCGGC
TCCGTGCGGATGAGGGACTTGCGGAATCCACACCCTTCCTCAGCGTTCCTGAACCTGATT
GGCTTCGTGTCGAGAAGGGAGCTCGGGAGCATTGATGGAGTCCAGCAGATTTCTTTGGAG
GATGCTCTTTCCAGCCAAGAGGTGGAGGTCGCCTATATCTGCAGTGAGAGCTCCAGCCAT
GAGGACTACATCAGGCAGTTCCTTAATGCTGGCAAGCACGTCCTTGTGGAATACCCCATG
ACACTGTCATTGGCGGCCGCTCAGGAACTGTGGGAGCTGGCTGAGCAGAAAGGAAAAGTC
TTGCACGAGGAGCATGTTGAACTCTTGATGGAGGAATTCGCTTTCCTGAAAAAAGAAGTG
GTGGGGAAAGACCTGCTGAAAGGGTCGCTCCTCTTCACAGCTGGCCCGTTGGAAGAAGAG
CGGTTTGGCTTCCCTGCATTCAGCGGCATCTCTCGCCTGACCTGGCTGGTCTCCCTCTTT
GGGGAGCTTTCTCTTGTGTCTGCCACTTTGGAAGAGCGAAAGGAAGATCAGTATATGAAA
ATGACAGTGTGTCTGGAGACAGAGAAGAAAAGTCCACTGTCATGGATTGAAGAAAAAGGA
CCTGGTCTAAAACGAAACAGATATTTAAGCTTCCATTTCAAGTCTGGGTCCTTGGAGAAT
GTGCCAAATGTAGGAGTGAATAAGAACATATTTCTGAAAGATCAAAATATATTTGTCCAG
AAACTCTTGGGCCAGTTCTCTGAGAAGGAACTGGCTGCTGAAAAGAAACGCATCCTGCAC
TGCCTGGGGCTTGCAGAAGAAATCCAGAAATATTGCTGTTCAAGGAAGTAA

Protein Properties

Number of Residues

296

Molecular Weight

33428.225

Theoretical pI

6.449

Pfam Domain Function

GFO_IDH_MocA (PF01408 )
Biliv-reduc_cat (PF09166 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Biliverdin reductase A
MNAEPERKFGVVVVGVGRAGSVRMRDLRNPHPSSAFLNLIGFVSRRELGSIDGVQQISLE
DALSSQEVEVAYICSESSSHEDYIRQFLNAGKHVLVEYPMTLSLAAAQELWELAEQKGKV
LHEEHVELLMEEFAFLKKEVVGKDLLKGSLLFTAGPLEEERFGFPAFSGISRLTWLVSLF
GELSLVSATLEERKEDQYMKMTVCLETEKKSPLSWIEEKGPGLKRNRYLSFHFKSGSLEN
VPNVGVNKNIFLKDQNIFVQKLLGQFSEKELAAEKKRILHCLGLAEEIQKYCCSRK

External Links

GenBank ID Protein

33589854

UniProtKB/Swiss-Prot ID

P53004

UniProtKB/Swiss-Prot Entry Name

BIEA_HUMAN

PDB IDs