Identification
HMDB Protein ID CDBP04080
Secondary Accession Numbers Not Available
Name Poly [ADP-ribose] polymerase 15
Description Not Available
Synonyms
  1. B-aggressive lymphoma protein 3
  2. PARP-15
  3. ADP-ribosyltransferase diphtheria toxin-like 7
  4. ARTD7
Gene Name PARP15
Protein Type Enzyme
Biological Properties
General Function Involved in NAD+ ADP-ribosyltransferase activity
Specific Function Transcriptional repressor. Has ADP-ribosyltransferase activity.
GO Classification
Biological Process
regulation of transcription, DNA-dependent
transcription, DNA-dependent
Cellular Component
nucleus
Function
catalytic activity
transferase activity
nad+ adp-ribosyltransferase activity
transferase activity, transferring pentosyl groups
transferase activity, transferring glycosyl groups
Molecular Function
NAD+ ADP-ribosyltransferase activity
Cellular Location
  1. Nucleus (Probable)
Pathways
Gene Properties
Chromosome Location 3
Locus 3q21.1
SNPs PARP15
Gene Sequence
>1971 bp
ATGCACGGAGTTGCAGGTGTTACTTCCAGAGCCGGACGAGATCGGGAGGCGGGGAGCATG
CTGCCGGCCGGGAACCGTGGGGCGCGGAAGGCCTCCCGGCGCTCTTCCTCCCGGAGTATG
TCCAGAGACAACAAGTTCAGCAAGAAAGATTGTCTTTCAATCAGGAATGTTGTAGCTTCA
ATCCAAACCAAAGAAGGTCTGAATCTCAAGTTGATAAGTGGAGATGTTCTGTACATCTGG
GCCGATGTCATTGTCAACAGCGTTCCCATGAATCTTCAGCTTGGAGGAGGACCACTATCT
CGGGCATTTTTGCAGAAAGCTGGTCCCATGCTCCAGAAAGAGTTAGATGACAGAAGGCGG
GAAACAGAGGAAAAAGTAGGTAACATATTCATGACAAGCGGCTGCAATCTGGACTGCAAA
GCTGTGCTCCATGCTGTGGCTCCATACTGGAATAATGGAGCAGAGACTTCTTGGCAGATC
ATGGCAAATATAATCAAGAAATGTTTGACAACTGTAGAAGTGCTATCTTTCTCATCAATC
ACATTTCCCATGATTGGAACAGGAAGTTTGCAGTTTCCCAAAGCTGTTTTTGCTAAACTA
ATCCTTTCAGAAGTGTTCGAATACAGTAGCAGCACAAGGCCGATAACTAGCCCTTTACAA
GAAGTCCACTTTCTGGTATATACAAATGACGATGAAGGCTGTCAGGCATTTTTAGATGAA
TTCACTAACTGGTCAAGAATAAATCCCAACAAGGCCAGGATTCCCATGGCAGGAGATACC
CAAGGTGTGGTCGGGACTGTCTCTAAGCCTTGTTTCACAGCATATGAAATGAAAATCGGT
GCAATTACTTTTCAGGTTGCTACTGGAGATATAGCCACTGAACAGGTAGATGTTATTGTA
AACTCAACAGCAAGGACATTTAATCGGAAATCAGGTGTGTCAAGAGCTATTTTAGAAGGT
GCTGGACAAGCTGTGGAAAGTGAATGTGCTGTACTAGCTGCACAGCCTCACAGAGATTTT
ATAATTACACCAGGTGGATGCTTAAAGTGCAAAATAATAATTCATGTTCCTGGGGGAAAA
GATGTCAGGAAAACGGTCACCAGTGTTCTAGAAGAGTGTGAACAGAGGAAGTACACATCG
GTTTCCCTTCCAGCCATTGGAACAGGAAATGCCGGAAAAAACCCTATCACAGTTGCTGAT
AACATAATCGATGCTATTGTAGACTTCTCATCACAACATTCCACCCCATCATTAAAAACA
GTTAAAGTTGTCATTTTTCAACCTGAGCTGCTAAATATATTCTACGACAGCATGAAAAAA
AGAGACCTCTCTGCATCACTGAACTTTCAGTCCACATTCTCCATGACTACATGTAATCTT
CCTGAACACTGGACTGACATGAATCATCAGCTGTTTTGCATGGTCCAGCTAGAGCCAGGA
CAATCAGAATATAATACCATAAAGGACAAGTTCACCCGAACTTGTTCTTCCTACGCAATA
GAGAAGATTGAGAGGATACAGAATGCATTTCTCTGGCAGAGCTACCAGGTAAAGAAAAGG
CAAATGGATATCAAGAATGACCATAAGAATAATGAGAGACTCCTCTTCCATGGGACAGAT
GCAGACTCAGTGCCATATGTCAATCAGCACGGCTTTAATAGAAGTTGTGCTGGGAAAAAT
GCTGTATCCTATGGAAAAGGAACCTATTTTGCTGTGGATGCCAGTTATTCTGCCAAGGAC
ACCTACTCCAAGCCAGACAGCAATGGGAGAAAGCACATGTACGTTGTGCGAGTACTTACT
GGAGTCTTCACAAAGGGACGTGCAGGATTAGTCACCCCTCCACCCAAGAATCCTCACAAT
CCCACAGATCTCTTTGACTCAGTGACAAACAATACACGATCTCCAAAGCTATTTGTGGTA
TTCTTTGATAATCAGGCTTACCCAGAATATCTCATAACTTTCACGGCTTAA
Protein Properties
Number of Residues 656
Molecular Weight 74575.465
Theoretical pI 8.815
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Poly [ADP-ribose] polymerase 15
MHGVAGVTSRAGRDREAGSMLPAGNRGARKASRRSSSRSMSRDNKFSKKDCLSIRNVVAS
IQTKEGLNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDRRR
ETEEKVGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSFSSI
TFPMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAFLDE
FTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGAITFQVATGDIATEQVDVIV
NSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFIITPGGCLKCKIIIHVPGGK
DVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQHSTPSLKT
VKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNLPEHWTDMNHQLFCMVQLEPG
QSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTD
ADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLT
GVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFTA
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q460N3
UniProtKB/Swiss-Prot Entry Name PAR15_HUMAN
PDB IDs
GenBank Gene ID DQ063586
GeneCard ID PARP15
GenAtlas ID PARP15
HGNC ID HGNC:26876
References
General References Not Available