Identification |
HMDB Protein ID
| CDBP04080 |
Secondary Accession Numbers
| Not Available |
Name
| Poly [ADP-ribose] polymerase 15 |
Description
| Not Available |
Synonyms
|
- B-aggressive lymphoma protein 3
- PARP-15
- ADP-ribosyltransferase diphtheria toxin-like 7
- ARTD7
|
Gene Name
| PARP15 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in NAD+ ADP-ribosyltransferase activity |
Specific Function
| Transcriptional repressor. Has ADP-ribosyltransferase activity.
|
GO Classification
|
Biological Process |
regulation of transcription, DNA-dependent |
transcription, DNA-dependent |
Cellular Component |
nucleus |
Function |
catalytic activity |
transferase activity |
nad+ adp-ribosyltransferase activity |
transferase activity, transferring pentosyl groups |
transferase activity, transferring glycosyl groups |
Molecular Function |
NAD+ ADP-ribosyltransferase activity |
|
Cellular Location
|
- Nucleus (Probable)
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| 3 |
Locus
| 3q21.1 |
SNPs
| PARP15 |
Gene Sequence
|
>1971 bp
ATGCACGGAGTTGCAGGTGTTACTTCCAGAGCCGGACGAGATCGGGAGGCGGGGAGCATG
CTGCCGGCCGGGAACCGTGGGGCGCGGAAGGCCTCCCGGCGCTCTTCCTCCCGGAGTATG
TCCAGAGACAACAAGTTCAGCAAGAAAGATTGTCTTTCAATCAGGAATGTTGTAGCTTCA
ATCCAAACCAAAGAAGGTCTGAATCTCAAGTTGATAAGTGGAGATGTTCTGTACATCTGG
GCCGATGTCATTGTCAACAGCGTTCCCATGAATCTTCAGCTTGGAGGAGGACCACTATCT
CGGGCATTTTTGCAGAAAGCTGGTCCCATGCTCCAGAAAGAGTTAGATGACAGAAGGCGG
GAAACAGAGGAAAAAGTAGGTAACATATTCATGACAAGCGGCTGCAATCTGGACTGCAAA
GCTGTGCTCCATGCTGTGGCTCCATACTGGAATAATGGAGCAGAGACTTCTTGGCAGATC
ATGGCAAATATAATCAAGAAATGTTTGACAACTGTAGAAGTGCTATCTTTCTCATCAATC
ACATTTCCCATGATTGGAACAGGAAGTTTGCAGTTTCCCAAAGCTGTTTTTGCTAAACTA
ATCCTTTCAGAAGTGTTCGAATACAGTAGCAGCACAAGGCCGATAACTAGCCCTTTACAA
GAAGTCCACTTTCTGGTATATACAAATGACGATGAAGGCTGTCAGGCATTTTTAGATGAA
TTCACTAACTGGTCAAGAATAAATCCCAACAAGGCCAGGATTCCCATGGCAGGAGATACC
CAAGGTGTGGTCGGGACTGTCTCTAAGCCTTGTTTCACAGCATATGAAATGAAAATCGGT
GCAATTACTTTTCAGGTTGCTACTGGAGATATAGCCACTGAACAGGTAGATGTTATTGTA
AACTCAACAGCAAGGACATTTAATCGGAAATCAGGTGTGTCAAGAGCTATTTTAGAAGGT
GCTGGACAAGCTGTGGAAAGTGAATGTGCTGTACTAGCTGCACAGCCTCACAGAGATTTT
ATAATTACACCAGGTGGATGCTTAAAGTGCAAAATAATAATTCATGTTCCTGGGGGAAAA
GATGTCAGGAAAACGGTCACCAGTGTTCTAGAAGAGTGTGAACAGAGGAAGTACACATCG
GTTTCCCTTCCAGCCATTGGAACAGGAAATGCCGGAAAAAACCCTATCACAGTTGCTGAT
AACATAATCGATGCTATTGTAGACTTCTCATCACAACATTCCACCCCATCATTAAAAACA
GTTAAAGTTGTCATTTTTCAACCTGAGCTGCTAAATATATTCTACGACAGCATGAAAAAA
AGAGACCTCTCTGCATCACTGAACTTTCAGTCCACATTCTCCATGACTACATGTAATCTT
CCTGAACACTGGACTGACATGAATCATCAGCTGTTTTGCATGGTCCAGCTAGAGCCAGGA
CAATCAGAATATAATACCATAAAGGACAAGTTCACCCGAACTTGTTCTTCCTACGCAATA
GAGAAGATTGAGAGGATACAGAATGCATTTCTCTGGCAGAGCTACCAGGTAAAGAAAAGG
CAAATGGATATCAAGAATGACCATAAGAATAATGAGAGACTCCTCTTCCATGGGACAGAT
GCAGACTCAGTGCCATATGTCAATCAGCACGGCTTTAATAGAAGTTGTGCTGGGAAAAAT
GCTGTATCCTATGGAAAAGGAACCTATTTTGCTGTGGATGCCAGTTATTCTGCCAAGGAC
ACCTACTCCAAGCCAGACAGCAATGGGAGAAAGCACATGTACGTTGTGCGAGTACTTACT
GGAGTCTTCACAAAGGGACGTGCAGGATTAGTCACCCCTCCACCCAAGAATCCTCACAAT
CCCACAGATCTCTTTGACTCAGTGACAAACAATACACGATCTCCAAAGCTATTTGTGGTA
TTCTTTGATAATCAGGCTTACCCAGAATATCTCATAACTTTCACGGCTTAA
|
Protein Properties |
Number of Residues
| 656 |
Molecular Weight
| 74575.465 |
Theoretical pI
| 8.815 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Poly [ADP-ribose] polymerase 15
MHGVAGVTSRAGRDREAGSMLPAGNRGARKASRRSSSRSMSRDNKFSKKDCLSIRNVVAS
IQTKEGLNLKLISGDVLYIWADVIVNSVPMNLQLGGGPLSRAFLQKAGPMLQKELDDRRR
ETEEKVGNIFMTSGCNLDCKAVLHAVAPYWNNGAETSWQIMANIIKKCLTTVEVLSFSSI
TFPMIGTGSLQFPKAVFAKLILSEVFEYSSSTRPITSPLQEVHFLVYTNDDEGCQAFLDE
FTNWSRINPNKARIPMAGDTQGVVGTVSKPCFTAYEMKIGAITFQVATGDIATEQVDVIV
NSTARTFNRKSGVSRAILEGAGQAVESECAVLAAQPHRDFIITPGGCLKCKIIIHVPGGK
DVRKTVTSVLEECEQRKYTSVSLPAIGTGNAGKNPITVADNIIDAIVDFSSQHSTPSLKT
VKVVIFQPELLNIFYDSMKKRDLSASLNFQSTFSMTTCNLPEHWTDMNHQLFCMVQLEPG
QSEYNTIKDKFTRTCSSYAIEKIERIQNAFLWQSYQVKKRQMDIKNDHKNNERLLFHGTD
ADSVPYVNQHGFNRSCAGKNAVSYGKGTYFAVDASYSAKDTYSKPDSNGRKHMYVVRVLT
GVFTKGRAGLVTPPPKNPHNPTDLFDSVTNNTRSPKLFVVFFDNQAYPEYLITFTA
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| Q460N3 |
UniProtKB/Swiss-Prot Entry Name
| PAR15_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| DQ063586 |
GeneCard ID
| PARP15 |
GenAtlas ID
| PARP15 |
HGNC ID
| HGNC:26876 |
References |
General References
| Not Available |