Identification
HMDB Protein ID CDBP04094
Secondary Accession Numbers Not Available
Name tRNA 2'-phosphotransferase 1
Description Not Available
Synonyms Not Available
Gene Name TRPT1
Protein Type Enzyme
Biological Properties
General Function Involved in transferase activity, transferring phosphorus-containing groups
Specific Function Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate (Probable).
GO Classification
Biological Process
tRNA splicing, via endonucleolytic cleavage and ligation
Function
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
Molecular Function
transferase activity, transferring phosphorus-containing groups
tRNA 2'-phosphotransferase activity
Process
rna metabolic process
metabolic process
macromolecule metabolic process
cellular macromolecule metabolic process
rna processing
rna splicing
rna splicing, via endonucleolytic cleavage and ligation
trna splicing, via endonucleolytic cleavage and ligation
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location 11
Locus 11q13.1
SNPs TRPT1
Gene Sequence
>762 bp
ATGAACTTCTCTGGAGGAGGGAGGCAGGAAGCAGCAGGGTCCAGGGGTAGAAGGGCTCCC
AGACCCCGAGAACAGGACCGAGACGTGCAGCTGTCCAAGGCTCTGTCCTATGCCCTGCGC
CATGGGGCCTTGAAGCTGGGGCTTCCCATGGGAGCTGATGGCTTCGTGCCCCTGGGCACC
CTCCTGCAGTTGCCCCAGTTCCGCGGCTTCTCTGCTGAAGATGTGCAGCGCGTGGTGGAC
ACCAATAGGAAGCAGCGGTTCGCCCTGCAGCTGGGGGATCCCAGCACTGGCCTTCTCATC
CGGGCCAACCAGGGCCATTCCCTGCAGGTACCTAAGTTGGAGCTGATGCCCCTGGAGACA
CCGCAGGCCCTGCCCCCGATGCTAGTCCATGGTACATTCTGGAAGCACTGGCCATCCATC
CTACTCAAAGGCCTGTCCTGCCAGGGAAGGACGCACATTCACCTGGCCCCAGGACTGCCT
GGAGACCCCGGTATCATCAGTGGCATGCGGTCCCATTGTGAAATAGCTGTGTTCATCGAT
GGACCCCTGGCTCTGGCAGATGGAATACCCTTCTTCCGCTCTGCCAATGGGGTGATTCTG
ACTCCAGGGAATACTGATGGCTTCCTCCTTCCCAAGTACTTCAAGGAGGCCCTGCAGCTA
CGCCCTACCCGAAAGCCCCTTTCCTTGGCTGGTGATGAAGAGACAGAGTGTCAGAGTAGC
CCCAAGCACAGCTCCAGAGAAAGGAGGAGGATCCAACAATAA
Protein Properties
Number of Residues 253
Molecular Weight 27741.69
Theoretical pI 9.985
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>tRNA 2'-phosphotransferase 1
MNFSGGGRQEAAGSRGRRAPRPREQDRDVQLSKALSYALRHGALKLGLPMGADGFVPLGT
LLQLPQFRGFSAEDVQRVVDTNRKQRFALQLGDPSTGLLIRANQGHSLQVPKLELMPLET
PQALPPMLVHGTFWKHWPSILLKGLSCQGRTHIHLAPGLPGDPGIISGMRSHCEIAVFID
GPLALADGIPFFRSANGVILTPGNTDGFLLPKYFKEALQLRPTRKPLSLAGDEETECQSS
PKHSSRERRRIQQ
GenBank ID Protein 238550153
UniProtKB/Swiss-Prot ID Q86TN4
UniProtKB/Swiss-Prot Entry Name TRPT1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_001033678.3
GeneCard ID TRPT1
GenAtlas ID TRPT1
HGNC ID HGNC:20316
References
General References Not Available