Identification |
HMDB Protein ID
| CDBP04094 |
Secondary Accession Numbers
| Not Available |
Name
| tRNA 2'-phosphotransferase 1 |
Description
| Not Available |
Synonyms
|
Not Available
|
Gene Name
| TRPT1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in transferase activity, transferring phosphorus-containing groups |
Specific Function
| Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate (Probable).
|
GO Classification
|
Biological Process |
tRNA splicing, via endonucleolytic cleavage and ligation |
Function |
catalytic activity |
transferase activity |
transferase activity, transferring phosphorus-containing groups |
Molecular Function |
transferase activity, transferring phosphorus-containing groups |
tRNA 2'-phosphotransferase activity |
Process |
rna metabolic process |
metabolic process |
macromolecule metabolic process |
cellular macromolecule metabolic process |
rna processing |
rna splicing |
rna splicing, via endonucleolytic cleavage and ligation |
trna splicing, via endonucleolytic cleavage and ligation |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| 11 |
Locus
| 11q13.1 |
SNPs
| TRPT1 |
Gene Sequence
|
>762 bp
ATGAACTTCTCTGGAGGAGGGAGGCAGGAAGCAGCAGGGTCCAGGGGTAGAAGGGCTCCC
AGACCCCGAGAACAGGACCGAGACGTGCAGCTGTCCAAGGCTCTGTCCTATGCCCTGCGC
CATGGGGCCTTGAAGCTGGGGCTTCCCATGGGAGCTGATGGCTTCGTGCCCCTGGGCACC
CTCCTGCAGTTGCCCCAGTTCCGCGGCTTCTCTGCTGAAGATGTGCAGCGCGTGGTGGAC
ACCAATAGGAAGCAGCGGTTCGCCCTGCAGCTGGGGGATCCCAGCACTGGCCTTCTCATC
CGGGCCAACCAGGGCCATTCCCTGCAGGTACCTAAGTTGGAGCTGATGCCCCTGGAGACA
CCGCAGGCCCTGCCCCCGATGCTAGTCCATGGTACATTCTGGAAGCACTGGCCATCCATC
CTACTCAAAGGCCTGTCCTGCCAGGGAAGGACGCACATTCACCTGGCCCCAGGACTGCCT
GGAGACCCCGGTATCATCAGTGGCATGCGGTCCCATTGTGAAATAGCTGTGTTCATCGAT
GGACCCCTGGCTCTGGCAGATGGAATACCCTTCTTCCGCTCTGCCAATGGGGTGATTCTG
ACTCCAGGGAATACTGATGGCTTCCTCCTTCCCAAGTACTTCAAGGAGGCCCTGCAGCTA
CGCCCTACCCGAAAGCCCCTTTCCTTGGCTGGTGATGAAGAGACAGAGTGTCAGAGTAGC
CCCAAGCACAGCTCCAGAGAAAGGAGGAGGATCCAACAATAA
|
Protein Properties |
Number of Residues
| 253 |
Molecular Weight
| 27741.69 |
Theoretical pI
| 9.985 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>tRNA 2'-phosphotransferase 1
MNFSGGGRQEAAGSRGRRAPRPREQDRDVQLSKALSYALRHGALKLGLPMGADGFVPLGT
LLQLPQFRGFSAEDVQRVVDTNRKQRFALQLGDPSTGLLIRANQGHSLQVPKLELMPLET
PQALPPMLVHGTFWKHWPSILLKGLSCQGRTHIHLAPGLPGDPGIISGMRSHCEIAVFID
GPLALADGIPFFRSANGVILTPGNTDGFLLPKYFKEALQLRPTRKPLSLAGDEETECQSS
PKHSSRERRRIQQ
|
External Links |
GenBank ID Protein
| 238550153 |
UniProtKB/Swiss-Prot ID
| Q86TN4 |
UniProtKB/Swiss-Prot Entry Name
| TRPT1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_001033678.3 |
GeneCard ID
| TRPT1 |
GenAtlas ID
| TRPT1 |
HGNC ID
| HGNC:20316 |
References |
General References
| Not Available |