Identification |
HMDB Protein ID
| CDBP00782 |
Secondary Accession Numbers
| Not Available |
Name
| Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic |
Description
| Not Available |
Synonyms
|
- GPD-C
- GPDH-C
|
Gene Name
| GPD1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in oxidoreductase activity |
Specific Function
| Not Available |
GO Classification
|
Biological Process |
small molecule metabolic process |
NADH oxidation |
gluconeogenesis |
phosphatidic acid biosynthetic process |
triglyceride biosynthetic process |
glycerol-3-phosphate catabolic process |
Cellular Component |
cytosol |
mitochondrion |
glycerol-3-phosphate dehydrogenase complex |
Component |
intracellular part |
cytoplasm |
macromolecular complex |
protein complex |
glycerol-3-phosphate dehydrogenase complex |
cell part |
Function |
protein homodimerization activity |
glycerol-3-phosphate dehydrogenase [nad+] activity |
binding |
nucleotide binding |
catalytic activity |
nad or nadh binding |
oxidoreductase activity, acting on the ch-oh group of donors, nad or nadp as acceptor |
protein binding |
coenzyme binding |
cofactor binding |
oxidoreductase activity, acting on ch-oh group of donors |
oxidoreductase activity |
identical protein binding |
Molecular Function |
glycerol-3-phosphate dehydrogenase activity |
NAD binding |
glycerol-3-phosphate dehydrogenase [NAD+] activity |
Process |
metabolic process |
primary metabolic process |
carbohydrate metabolic process |
small molecule metabolic process |
alcohol metabolic process |
polyol metabolic process |
alditol metabolic process |
glycerol metabolic process |
glycerol-3-phosphate metabolic process |
oxidation reduction |
glycerol-3-phosphate catabolic process |
|
Cellular Location
|
- Cytoplasm
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Glycerol Phosphate Shuttle | | Not Available | Glycerolipid Metabolism | | | Mitochondrial Electron Transport Chain | | | Phospholipid Biosynthesis | | | Glycerophospholipid metabolism | Not Available | |
|
Gene Properties |
Chromosome Location
| 12 |
Locus
| 12q12-q13 |
SNPs
| GPD1 |
Gene Sequence
|
>1050 bp
ATGGCTAGCAAGAAAGTCTGCATTGTAGGCTCCGGGAACTGGGGCTCAGCCATCGCCAAG
ATCGTGGGTGGCAATGCAGCCCAGCTGGCACAGTTTGACCCACGGGTGACCATGTGGGTA
TTTGAGGAAGACATTGGAGGCAAAAAGCTGACTGAGATCATCAACACGCAGCATGAGAAT
GTCAAATACCTGCCAGGGCACAAGTTGCCCCCAAATGTGGTGGCTGTCCCAGATGTGGTC
CAGGCTGCAGAGGATGCTGACATCCTGATCTTTGTGGTGCCCCATCAGTTCATCGGCAAG
ATCTGTGACCAGCTCAAGGGCCATCTGAAGGCAAACGCCACTGGCATATCTCTTATTAAG
GGGGTAGACGAGGGCCCCAATGGGCTGAAGCTCATCTCGGAAGTGATTGGGGAGCGCCTC
GGCATCCCCATGAGTGTGCTGATGGGGGCCAACATTGCCAGCGAGGTGGCTGATGAGAAG
TTCTGTGAGACAACCATTGGCTGCAAGGACCCGGCCCAGGGACAACTCCTGAAAGAGCTG
ATGCAGACACCAAACTTCCGTATCACAGTGGTGCAAGAGGTGGACACAGTAGAGATCTGT
GGAGCCTTAAAGAATGTAGTGGCCGTGGGGGCTGGCTTCTGTGATGGCCTGGGCTTTGGC
GACAACACCAAGGCGGCAGTGATCCGGCTGGGACTCATGGAGATGATAGCCTTCGCCAAG
CTCTTCTGCAGTGGCCCTGTGTCCTCTGCCACCTTCTTGGAGAGCTGTGGTGTTGCTGAC
CTGATCACTACCTGCTATGGAGGGCGGAACCGGAAAGTGGCTGAGGCCTTTGCGCGTACA
GGAAAGTCCATTGAGCAGCTGGAGAAAGAGTTGCTGAATGGGCAGAAACTGCAGGGGCCC
GAGACAGCCCGGGAGCTATACAGCATCCTCCAGCACAAGGGCCTGGTAGACAAGTTTCCC
TTGTTCATGGCTGTGTACAAGGTGTGCTACGAGGGCCAGCCAGTGGGTGAATTCATCCAC
TGCCTGCAGAATCATCCAGAACATATGTGA
|
Protein Properties |
Number of Residues
| 349 |
Molecular Weight
| 37567.4 |
Theoretical pI
| 6.176 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic
MASKKVCIVGSGNWGSAIAKIVGGNAAQLAQFDPRVTMWVFEEDIGGKKLTEIINTQHEN
VKYLPGHKLPPNVVAVPDVVQAAEDADILIFVVPHQFIGKICDQLKGHLKANATGISLIK
GVDEGPNGLKLISEVIGERLGIPMSVLMGANIASEVADEKFCETTIGCKDPAQGQLLKEL
MQTPNFRITVVQEVDTVEICGALKNVVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAK
LFCSGPVSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKELLNGQKLQGP
ETARELYSILQHKGLVDKFPLFMAVYKVCYEGQPVGEFIHCLQNHPEHM
|
External Links |
GenBank ID Protein
| 21594877 |
UniProtKB/Swiss-Prot ID
| P21695 |
UniProtKB/Swiss-Prot Entry Name
| GPDA_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| BC032234 |
GeneCard ID
| GPD1 |
GenAtlas ID
| GPD1 |
HGNC ID
| HGNC:4455 |
References |
General References
| Not Available |