Identification
HMDB Protein ID CDBP00782
Secondary Accession Numbers Not Available
Name Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic
Description Not Available
Synonyms
  1. GPD-C
  2. GPDH-C
Gene Name GPD1
Protein Type Enzyme
Biological Properties
General Function Involved in oxidoreductase activity
Specific Function Not Available
GO Classification
Biological Process
small molecule metabolic process
NADH oxidation
gluconeogenesis
phosphatidic acid biosynthetic process
triglyceride biosynthetic process
glycerol-3-phosphate catabolic process
Cellular Component
cytosol
mitochondrion
glycerol-3-phosphate dehydrogenase complex
Component
intracellular part
cytoplasm
macromolecular complex
protein complex
glycerol-3-phosphate dehydrogenase complex
cell part
Function
protein homodimerization activity
glycerol-3-phosphate dehydrogenase [nad+] activity
binding
nucleotide binding
catalytic activity
nad or nadh binding
oxidoreductase activity, acting on the ch-oh group of donors, nad or nadp as acceptor
protein binding
coenzyme binding
cofactor binding
oxidoreductase activity, acting on ch-oh group of donors
oxidoreductase activity
identical protein binding
Molecular Function
glycerol-3-phosphate dehydrogenase activity
NAD binding
glycerol-3-phosphate dehydrogenase [NAD+] activity
Process
metabolic process
primary metabolic process
carbohydrate metabolic process
small molecule metabolic process
alcohol metabolic process
polyol metabolic process
alditol metabolic process
glycerol metabolic process
glycerol-3-phosphate metabolic process
oxidation reduction
glycerol-3-phosphate catabolic process
Cellular Location
  1. Cytoplasm
Pathways
Gene Properties
Chromosome Location 12
Locus 12q12-q13
SNPs GPD1
Gene Sequence
>1050 bp
ATGGCTAGCAAGAAAGTCTGCATTGTAGGCTCCGGGAACTGGGGCTCAGCCATCGCCAAG
ATCGTGGGTGGCAATGCAGCCCAGCTGGCACAGTTTGACCCACGGGTGACCATGTGGGTA
TTTGAGGAAGACATTGGAGGCAAAAAGCTGACTGAGATCATCAACACGCAGCATGAGAAT
GTCAAATACCTGCCAGGGCACAAGTTGCCCCCAAATGTGGTGGCTGTCCCAGATGTGGTC
CAGGCTGCAGAGGATGCTGACATCCTGATCTTTGTGGTGCCCCATCAGTTCATCGGCAAG
ATCTGTGACCAGCTCAAGGGCCATCTGAAGGCAAACGCCACTGGCATATCTCTTATTAAG
GGGGTAGACGAGGGCCCCAATGGGCTGAAGCTCATCTCGGAAGTGATTGGGGAGCGCCTC
GGCATCCCCATGAGTGTGCTGATGGGGGCCAACATTGCCAGCGAGGTGGCTGATGAGAAG
TTCTGTGAGACAACCATTGGCTGCAAGGACCCGGCCCAGGGACAACTCCTGAAAGAGCTG
ATGCAGACACCAAACTTCCGTATCACAGTGGTGCAAGAGGTGGACACAGTAGAGATCTGT
GGAGCCTTAAAGAATGTAGTGGCCGTGGGGGCTGGCTTCTGTGATGGCCTGGGCTTTGGC
GACAACACCAAGGCGGCAGTGATCCGGCTGGGACTCATGGAGATGATAGCCTTCGCCAAG
CTCTTCTGCAGTGGCCCTGTGTCCTCTGCCACCTTCTTGGAGAGCTGTGGTGTTGCTGAC
CTGATCACTACCTGCTATGGAGGGCGGAACCGGAAAGTGGCTGAGGCCTTTGCGCGTACA
GGAAAGTCCATTGAGCAGCTGGAGAAAGAGTTGCTGAATGGGCAGAAACTGCAGGGGCCC
GAGACAGCCCGGGAGCTATACAGCATCCTCCAGCACAAGGGCCTGGTAGACAAGTTTCCC
TTGTTCATGGCTGTGTACAAGGTGTGCTACGAGGGCCAGCCAGTGGGTGAATTCATCCAC
TGCCTGCAGAATCATCCAGAACATATGTGA
Protein Properties
Number of Residues 349
Molecular Weight 37567.4
Theoretical pI 6.176
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic
MASKKVCIVGSGNWGSAIAKIVGGNAAQLAQFDPRVTMWVFEEDIGGKKLTEIINTQHEN
VKYLPGHKLPPNVVAVPDVVQAAEDADILIFVVPHQFIGKICDQLKGHLKANATGISLIK
GVDEGPNGLKLISEVIGERLGIPMSVLMGANIASEVADEKFCETTIGCKDPAQGQLLKEL
MQTPNFRITVVQEVDTVEICGALKNVVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAK
LFCSGPVSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKELLNGQKLQGP
ETARELYSILQHKGLVDKFPLFMAVYKVCYEGQPVGEFIHCLQNHPEHM
GenBank ID Protein 21594877
UniProtKB/Swiss-Prot ID P21695
UniProtKB/Swiss-Prot Entry Name GPDA_HUMAN
PDB IDs
GenBank Gene ID BC032234
GeneCard ID GPD1
GenAtlas ID GPD1
HGNC ID HGNC:4455
References
General References Not Available