Identification
HMDB Protein ID CDBP00852
Secondary Accession Numbers Not Available
Name GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1
Description Not Available
Synonyms
  1. CD296 antigen
  2. Mono(ADP-ribosyl)transferase 1
  3. ADP-ribosyltransferase C2 and C3 toxin-like 1
  4. ARTC1
Gene Name ART1
Protein Type Enzyme
Biological Properties
General Function Involved in NAD(P)+-protein-arginine ADP-ribosyltransferase activity
Specific Function Has ADP-ribosyltransferase activity toward GLP1R.
GO Classification
Biological Process
protein ADP-ribosylation
innate immune response
Cellular Component
sarcoplasmic reticulum membrane
integral to plasma membrane
cell surface
anchored to membrane
Function
catalytic activity
transferase activity
nad(p)+-protein-arginine adp-ribosyltransferase activity
transferase activity, transferring pentosyl groups
transferase activity, transferring glycosyl groups
Molecular Function
NAD(P)+-protein-arginine ADP-ribosyltransferase activity
NAD+ ADP-ribosyltransferase activity
Process
metabolic process
macromolecule metabolic process
protein amino acid adp-ribosylation
post-translational protein modification
macromolecule modification
protein modification process
Cellular Location
  1. GPI-anchor
  2. Lipid- anchor
  3. Sarcoplasmic reticulum membrane
Pathways
Gene Properties
Chromosome Location 11
Locus 11p15
SNPs ART1
Gene Sequence
>984 bp
ATGCAGATGCCTGCTATGATGTCTCTGCTTCTTGTGTCTGTGGGCCTCATGGAAGCACTT
CAGGCCCAGAGCCACCCCATCACACGACGAGACCTCTTCTCTCAAGAGATTCAGCTGGAC
ATGGCCCTGGCCTCCTTTGATGACCAGTACGCTGGCTGTGCTGCTGCCATGACAGCTGCT
CTCCCGGATCTCAACCACACGGAGTTCCAGGCCAACCAGGTGTATGCAGACAGCTGGACA
CTGGCAAGCAGCCAATGGCAGGAGCGTCAGGCCAGGTGGCCAGAGTGGAGTCTCAGCCCC
ACCCGTCCATCCCCGCCACCCCTGGGCTTCCGCGATGAGCATGGGGTGGCCCTCCTGGCC
TACACAGCCAACAGCCCCCTGCACAAGGAGTTCAATGCAGCCGTGCGTGAGGCGGGCCGC
TCCCGGGCCCACTACCTCCACCACTTCTCCTTCAAGACACTCCATTTCCTGCTGACTGAG
GCCCTGCAGCTCCTGGGCAGCGGCCAGCGTCCACCCCGGTGCCACCAGGTGTTCCGAGGT
GTGCACGGCCTGCGCTTCCGGCCAGCAGGGCCCCGGGCCACCGTGAGGCTGGGGGGCTTT
GCTTCTGCCTCCCTGAAGCATGTTGCAGCCCAGCAGTTTGGTGAGGACACCTTCTTCGGC
ATCTGGACCTGCCTTGGGGCCCCTATCAAGGGCTACTCCTTCTTCCCTGGAGAGGAAGAG
GTGCTGATCCCCCCCTTTGAGACCTTCCAAGTGATCAATGCCAGCAGACTGGCCCAGGGC
CCCGCCCGCATCTACCTCCGAGCCCTGGGCAAGCACAGCACCTACAACTGCGAGTACATC
AAAGACAAGAAGTGCAAGTCTGGGCCTTGCCATCTGGATAATTCAGCCATGGGTCAGAGC
CCCCTCTCTGCAGTCTGGTCTTTGCTGCTGCTGCTCTGGTTCCTCGTGGTGAGGGCCTTT
CCAGATGGTCCAGGCCTCCTTTGA
Protein Properties
Number of Residues 327
Molecular Weight 36334.32
Theoretical pI 8.276
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1
MQMPAMMSLLLVSVGLMEALQAQSHPITRRDLFSQEIQLDMALASFDDQYAGCAAAMTAA
LPDLNHTEFQANQVYADSWTLASSQWQERQARWPEWSLSPTRPSPPPLGFRDEHGVALLA
YTANSPLHKEFNAAVREAGRSRAHYLHHFSFKTLHFLLTEALQLLGSGQRPPRCHQVFRG
VHGLRFRPAGPRATVRLGGFASASLKHVAAQQFGEDTFFGIWTCLGAPIKGYSFFPGEEE
VLIPPFETFQVINASRLAQGPARIYLRALGKHSTYNCEYIKDKKCKSGPCHLDNSAMGQS
PLSAVWSLLLLLWFLVVRAFPDGPGLL
GenBank ID Protein 158634472
UniProtKB/Swiss-Prot ID P52961
UniProtKB/Swiss-Prot Entry Name NAR1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_004314.2
GeneCard ID ART1
GenAtlas ID ART1
HGNC ID HGNC:723
References
General References Not Available