Identification |
HMDB Protein ID
| CDBP00852 |
Secondary Accession Numbers
| Not Available |
Name
| GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 |
Description
| Not Available |
Synonyms
|
- CD296 antigen
- Mono(ADP-ribosyl)transferase 1
- ADP-ribosyltransferase C2 and C3 toxin-like 1
- ARTC1
|
Gene Name
| ART1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in NAD(P)+-protein-arginine ADP-ribosyltransferase activity |
Specific Function
| Has ADP-ribosyltransferase activity toward GLP1R.
|
GO Classification
|
Biological Process |
protein ADP-ribosylation |
innate immune response |
Cellular Component |
sarcoplasmic reticulum membrane |
integral to plasma membrane |
cell surface |
anchored to membrane |
Function |
catalytic activity |
transferase activity |
nad(p)+-protein-arginine adp-ribosyltransferase activity |
transferase activity, transferring pentosyl groups |
transferase activity, transferring glycosyl groups |
Molecular Function |
NAD(P)+-protein-arginine ADP-ribosyltransferase activity |
NAD+ ADP-ribosyltransferase activity |
Process |
metabolic process |
macromolecule metabolic process |
protein amino acid adp-ribosylation |
post-translational protein modification |
macromolecule modification |
protein modification process |
|
Cellular Location
|
- GPI-anchor
- Lipid- anchor
- Sarcoplasmic reticulum membrane
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| 11 |
Locus
| 11p15 |
SNPs
| ART1 |
Gene Sequence
|
>984 bp
ATGCAGATGCCTGCTATGATGTCTCTGCTTCTTGTGTCTGTGGGCCTCATGGAAGCACTT
CAGGCCCAGAGCCACCCCATCACACGACGAGACCTCTTCTCTCAAGAGATTCAGCTGGAC
ATGGCCCTGGCCTCCTTTGATGACCAGTACGCTGGCTGTGCTGCTGCCATGACAGCTGCT
CTCCCGGATCTCAACCACACGGAGTTCCAGGCCAACCAGGTGTATGCAGACAGCTGGACA
CTGGCAAGCAGCCAATGGCAGGAGCGTCAGGCCAGGTGGCCAGAGTGGAGTCTCAGCCCC
ACCCGTCCATCCCCGCCACCCCTGGGCTTCCGCGATGAGCATGGGGTGGCCCTCCTGGCC
TACACAGCCAACAGCCCCCTGCACAAGGAGTTCAATGCAGCCGTGCGTGAGGCGGGCCGC
TCCCGGGCCCACTACCTCCACCACTTCTCCTTCAAGACACTCCATTTCCTGCTGACTGAG
GCCCTGCAGCTCCTGGGCAGCGGCCAGCGTCCACCCCGGTGCCACCAGGTGTTCCGAGGT
GTGCACGGCCTGCGCTTCCGGCCAGCAGGGCCCCGGGCCACCGTGAGGCTGGGGGGCTTT
GCTTCTGCCTCCCTGAAGCATGTTGCAGCCCAGCAGTTTGGTGAGGACACCTTCTTCGGC
ATCTGGACCTGCCTTGGGGCCCCTATCAAGGGCTACTCCTTCTTCCCTGGAGAGGAAGAG
GTGCTGATCCCCCCCTTTGAGACCTTCCAAGTGATCAATGCCAGCAGACTGGCCCAGGGC
CCCGCCCGCATCTACCTCCGAGCCCTGGGCAAGCACAGCACCTACAACTGCGAGTACATC
AAAGACAAGAAGTGCAAGTCTGGGCCTTGCCATCTGGATAATTCAGCCATGGGTCAGAGC
CCCCTCTCTGCAGTCTGGTCTTTGCTGCTGCTGCTCTGGTTCCTCGTGGTGAGGGCCTTT
CCAGATGGTCCAGGCCTCCTTTGA
|
Protein Properties |
Number of Residues
| 327 |
Molecular Weight
| 36334.32 |
Theoretical pI
| 8.276 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1
MQMPAMMSLLLVSVGLMEALQAQSHPITRRDLFSQEIQLDMALASFDDQYAGCAAAMTAA
LPDLNHTEFQANQVYADSWTLASSQWQERQARWPEWSLSPTRPSPPPLGFRDEHGVALLA
YTANSPLHKEFNAAVREAGRSRAHYLHHFSFKTLHFLLTEALQLLGSGQRPPRCHQVFRG
VHGLRFRPAGPRATVRLGGFASASLKHVAAQQFGEDTFFGIWTCLGAPIKGYSFFPGEEE
VLIPPFETFQVINASRLAQGPARIYLRALGKHSTYNCEYIKDKKCKSGPCHLDNSAMGQS
PLSAVWSLLLLLWFLVVRAFPDGPGLL
|
External Links |
GenBank ID Protein
| 158634472 |
UniProtKB/Swiss-Prot ID
| P52961 |
UniProtKB/Swiss-Prot Entry Name
| NAR1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_004314.2 |
GeneCard ID
| ART1 |
GenAtlas ID
| ART1 |
HGNC ID
| HGNC:723 |
References |
General References
| Not Available |