Cannabis Compound Database: Showing Protein L-lactate dehydrogenase B chain (CDBP02352)

Identification Biological properties Gene properties Protein properties External links References XML Show 6 compounds

Identification

HMDB Protein ID

CDBP02352

Secondary Accession Numbers

Not Available

Name

L-lactate dehydrogenase B chain

Description

Not Available

Synonyms

LDH heart subunit
LDH-B
LDH-H
Renal carcinoma antigen NY-REN-46

Gene Name

LDHB

Protein Type

Enzyme

Biological Properties

General Function

Involved in oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Specific Function

Not Available

GO Classification

Biological Process
glycolysis
cellular carbohydrate metabolic process
pyruvate metabolic process
lactate metabolic process
NAD metabolic process
Cellular Component
cytosol
mitochondrion
Component
cell part
intracellular part
cytoplasm
Function
oxidoreductase activity, acting on ch-oh group of donors
oxidoreductase activity
catalytic activity
lactate dehydrogenase activity
l-lactate dehydrogenase activity
oxidoreductase activity, acting on the ch-oh group of donors, nad or nadp as acceptor
Molecular Function
NAD binding
L-lactate dehydrogenase activity
Process
metabolic process
primary metabolic process
carbohydrate metabolic process
cellular carbohydrate metabolic process
small molecule metabolic process
alcohol metabolic process
monosaccharide metabolic process
hexose metabolic process
glucose metabolic process
oxidation reduction
glucose catabolic process
glycolysis

Cellular Location

Cytoplasm

Pathways

Name	SMPDB/Pathwhiz	KEGG
pyruvate fermentation to lactate	Not Available	Not Available
Glycolysis / Gluconeogenesis	Not Available
Cysteine and methionine metabolism	Not Available

Gene Properties

Chromosome Location

Locus

12p12.2-p12.1

SNPs

LDHB

Gene Sequence

>1005 bp
ATGGCAACTCTTAAGGAAAAACTCATTGCACCAGTTGCGGAAGAAGAGGCAACAGTTCCA
AACAATAAGATCACTGTAGTGGGTGTTGGACAAGTTGGTATGGCGTGTGCTATCAGCATT
CTGGGAAAGTCTCTGGCTGATGAACTTGCTCTTGTGGATGTTTTGGAAGATAAGCTTAAA
GGAGAAATGATGGATCTGCAGCATGGGAGCTTATTTCTTCAGACACCTAAAATTGTGGCA
GATAAAGATTATTCTGTGACCGCCAATTCTAAGATTGTAGTGGTAACTGCAGGAGTCCGT
CAGCAAGAAGGGGAGAGTCGGCTCAATCTGGTGCAGAGAAATGTTAATGTCTTCAAATTC
ATTATTCCTCAGATCGTCAAGTACAGTCCTGATTGCATCATAATTGTGGTTTCCAACCCA
GTGGACATTCTTACGTATGTTACCTGGAAACTAAGTGGATTACCCAAACACCGCGTGATT
GGAAGTGGATGTAATCTGGATTCTGCTAGATTTCGCTACCTTATGGCTGAAAAACTTGGC
ATTCATCCCAGCAGCTGCCATGGATGGATTTTGGGGGAACATGGCGACTCAAGTGTGGCT
GTGTGGAGTGGTGTGAATGTGGCAGGTGTTTCTCTCCAGGAATTGAATCCAGAAATGGGA
ACTGACAATGATAGTGAAAATTGGAAGGAAGTGCATAAGATGGTGGTTGAAAGTGCCTAT
GAAGTCATCAAGCTAAAAGGATATACCAACTGGGCTATTGGATTAAGTGTGGCTGATCTT
ATTGAATCCATGTTGAAAAATCTATCCAGGATTCATCCCGTGTCAACAATGGTAAAGGGG
ATGTATGGCATTGAGAATGAAGTCTTCCTGAGCCTTCCATGTATCCTCAATGCCCGGGGA
TTAACCAGCGTTATCAACCAGAAGCTAAAGGATGATGAGGTTGCTCAGCTCAAGAAAAGT
GCAGATACCCTGTGGGACATCCAGAAGGACCTAAAAGACCTGTGA

Protein Properties

Number of Residues

334

Molecular Weight

36638.225

Theoretical pI

6.052

Pfam Domain Function

Ldh_1_C (PF02866 )
Ldh_1_N (PF00056 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>L-lactate dehydrogenase B chain
MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLK
GEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKF
IIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLG
IHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAY
EVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARG
LTSVINQKLKDDEVAQLKKSADTLWDIQKDLKDL

External Links

GenBank ID Protein

34329

UniProtKB/Swiss-Prot ID

P07195

UniProtKB/Swiss-Prot Entry Name

LDHB_HUMAN

PDB IDs