Identification
HMDB Protein ID CDBP00152
Secondary Accession Numbers Not Available
Name NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
Description Not Available
Synonyms
  1. CI-B14.5a
  2. Complex I-B14.5a
  3. NADH-ubiquinone oxidoreductase subunit B14.5a
Gene Name NDUFA7
Protein Type Enzyme
Biological Properties
General Function Involved in NADH dehydrogenase (ubiquinone) activity
Specific Function Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
GO Classification
Component
membrane
cell part
organelle membrane
organelle inner membrane
mitochondrial inner membrane
Function
oxidoreductase activity, acting on nadh or nadph
catalytic activity
nadh dehydrogenase activity
nadh dehydrogenase (quinone) activity
nadh dehydrogenase (ubiquinone) activity
oxidoreductase activity
Process
metabolic process
generation of precursor metabolites and energy
electron transport chain
respiratory electron transport chain
atp synthesis coupled electron transport
cellular metabolic process
Cellular Location
  1. Peripheral membrane protein
  2. Mitochondrion inner membrane
  3. Matrix side
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 19p13.2
SNPs NDUFA7
Gene Sequence
>342 bp
ATGGCGTCCGCCACCCGTCTCATCCAGCGGCTGCGGAACTGGGCGTCCGGGCATGACCTG
CAGGGGAAGCTGCAGCTACGCTACCAGGAGATCTCCAAGCGAACTCAGCCTCCTCCCAAG
CTCCCTGTGGGTCCTAGCCACAAGCTCTCCAACAATTACTATTGCACTCGCGATGGCCGC
CGGGAATCTGTGCCCCCTTCCATCATCATGTCGTCGCAGAAGGCGCTGGTGTCAGGCAAG
CCAGCAGAGAGCTCTGCTGTAGCTGCCACTGAGAAGAAGGCGGTGACTCCAGCTCCTCCC
ATAAAGAGGTGGGAGCTGTCCTCGGACCAGCCTTACCTGTGA
Protein Properties
Number of Residues 113
Molecular Weight 12551.3
Theoretical pI 10.8
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
MASATRLIQRLRNWASGHDLQGKLQLRYQEISKRTQPPPKLPVGPSHKLSNNYYCTRDGR
RESVPPSIIMSSQKALVSGKPAESSAVAATEKKAVTPAPPIKRWELSSDQPYL
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID O95182
UniProtKB/Swiss-Prot Entry Name NDUA7_HUMAN
PDB IDs Not Available
GenBank Gene ID AF050637
GeneCard ID NDUFA7
GenAtlas ID NDUFA7
HGNC ID HGNC:7691
References
General References Not Available