Identification |
HMDB Protein ID
| CDBP00152 |
Secondary Accession Numbers
| Not Available |
Name
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 |
Description
| Not Available |
Synonyms
|
- CI-B14.5a
- Complex I-B14.5a
- NADH-ubiquinone oxidoreductase subunit B14.5a
|
Gene Name
| NDUFA7 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in NADH dehydrogenase (ubiquinone) activity |
Specific Function
| Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone |
GO Classification
|
Component |
membrane |
cell part |
organelle membrane |
organelle inner membrane |
mitochondrial inner membrane |
Function |
oxidoreductase activity, acting on nadh or nadph |
catalytic activity |
nadh dehydrogenase activity |
nadh dehydrogenase (quinone) activity |
nadh dehydrogenase (ubiquinone) activity |
oxidoreductase activity |
Process |
metabolic process |
generation of precursor metabolites and energy |
electron transport chain |
respiratory electron transport chain |
atp synthesis coupled electron transport |
cellular metabolic process |
|
Cellular Location
|
- Peripheral membrane protein
- Mitochondrion inner membrane
- Matrix side
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 19p13.2 |
SNPs
| NDUFA7 |
Gene Sequence
|
>342 bp
ATGGCGTCCGCCACCCGTCTCATCCAGCGGCTGCGGAACTGGGCGTCCGGGCATGACCTG
CAGGGGAAGCTGCAGCTACGCTACCAGGAGATCTCCAAGCGAACTCAGCCTCCTCCCAAG
CTCCCTGTGGGTCCTAGCCACAAGCTCTCCAACAATTACTATTGCACTCGCGATGGCCGC
CGGGAATCTGTGCCCCCTTCCATCATCATGTCGTCGCAGAAGGCGCTGGTGTCAGGCAAG
CCAGCAGAGAGCTCTGCTGTAGCTGCCACTGAGAAGAAGGCGGTGACTCCAGCTCCTCCC
ATAAAGAGGTGGGAGCTGTCCTCGGACCAGCCTTACCTGTGA
|
Protein Properties |
Number of Residues
| 113 |
Molecular Weight
| 12551.3 |
Theoretical pI
| 10.8 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7
MASATRLIQRLRNWASGHDLQGKLQLRYQEISKRTQPPPKLPVGPSHKLSNNYYCTRDGR
RESVPPSIIMSSQKALVSGKPAESSAVAATEKKAVTPAPPIKRWELSSDQPYL
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| O95182 |
UniProtKB/Swiss-Prot Entry Name
| NDUA7_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF050637 |
GeneCard ID
| NDUFA7 |
GenAtlas ID
| NDUFA7 |
HGNC ID
| HGNC:7691 |
References |
General References
| Not Available |