Identification
HMDB Protein ID CDBP00170
Secondary Accession Numbers Not Available
Name NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
Description Not Available
Synonyms
  1. CI-13kD-B
  2. Complex I subunit B13
  3. Complex I-13kD-B
  4. NADH-ubiquinone oxidoreductase 13 kDa-B subunit
Gene Name NDUFA5
Protein Type Enzyme
Biological Properties
General Function Involved in oxidoreductase activity, acting on NADH or NADPH
Specific Function Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
GO Classification
Component
cell part
organelle membrane
organelle inner membrane
mitochondrial inner membrane
membrane
Function
catalytic activity
oxidoreductase activity
oxidoreductase activity, acting on nadh or nadph
Process
metabolic process
generation of precursor metabolites and energy
electron transport chain
respiratory electron transport chain
cellular metabolic process
Cellular Location
  1. Peripheral membrane protein
  2. Mitochondrion inner membrane
  3. Matrix side
Pathways
Gene Properties
Chromosome Location Chromosome:7
Locus 7q32
SNPs NDUFA5
Gene Sequence
>351 bp
ATGGCGGGTGTGCTGAAGAAGACCACTGGCCTTGTGGGATTGGCTGTGTGCAATACTCCT
CACGAGAGGCTAAGAATATTGTACACAAAGATTCTTGATGTTCTTGAGGAAATCCCTAAA
AATGCAGCATATAGAAAGTATACAGAACAGATTACAAATGAGAAGCTGGCTATGGTTAAA
GCGGAACCAGATGTTAAAAAATTAGAAGACCAACTTCAAGGCGGTCAATTAGAAGAGGTG
ATTCTTCAGGCTGAACATGAACTAAATCTGGCAAGAAAAATGAGGGAATGGAAACTATGG
GAGCCATTAGTGGAAGAGCCTCCTGCCGATCAGTGGAAATGGCCAATATAA
Protein Properties
Number of Residues 116
Molecular Weight 13458.6
Theoretical pI 5.81
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
MAGVLKKTTGLVGLAVCNTPHERLRILYTKILDVLEEIPKNAAYRKYTEQITNEKLAMVK
AEPDVKKLEDQLQGGQLEEVILQAEHELNLARKMREWKLWEPLVEEPPADQWKWPI
GenBank ID Protein 37674403
UniProtKB/Swiss-Prot ID Q16718
UniProtKB/Swiss-Prot Entry Name NDUA5_HUMAN
PDB IDs Not Available
GenBank Gene ID AC073323
GeneCard ID NDUFA5
GenAtlas ID NDUFA5
HGNC ID HGNC:7688
References
General References Not Available