Identification |
HMDB Protein ID
| CDBP00170 |
Secondary Accession Numbers
| Not Available |
Name
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 |
Description
| Not Available |
Synonyms
|
- CI-13kD-B
- Complex I subunit B13
- Complex I-13kD-B
- NADH-ubiquinone oxidoreductase 13 kDa-B subunit
|
Gene Name
| NDUFA5 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in oxidoreductase activity, acting on NADH or NADPH |
Specific Function
| Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone |
GO Classification
|
Component |
cell part |
organelle membrane |
organelle inner membrane |
mitochondrial inner membrane |
membrane |
Function |
catalytic activity |
oxidoreductase activity |
oxidoreductase activity, acting on nadh or nadph |
Process |
metabolic process |
generation of precursor metabolites and energy |
electron transport chain |
respiratory electron transport chain |
cellular metabolic process |
|
Cellular Location
|
- Peripheral membrane protein
- Mitochondrion inner membrane
- Matrix side
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:7 |
Locus
| 7q32 |
SNPs
| NDUFA5 |
Gene Sequence
|
>351 bp
ATGGCGGGTGTGCTGAAGAAGACCACTGGCCTTGTGGGATTGGCTGTGTGCAATACTCCT
CACGAGAGGCTAAGAATATTGTACACAAAGATTCTTGATGTTCTTGAGGAAATCCCTAAA
AATGCAGCATATAGAAAGTATACAGAACAGATTACAAATGAGAAGCTGGCTATGGTTAAA
GCGGAACCAGATGTTAAAAAATTAGAAGACCAACTTCAAGGCGGTCAATTAGAAGAGGTG
ATTCTTCAGGCTGAACATGAACTAAATCTGGCAAGAAAAATGAGGGAATGGAAACTATGG
GAGCCATTAGTGGAAGAGCCTCCTGCCGATCAGTGGAAATGGCCAATATAA
|
Protein Properties |
Number of Residues
| 116 |
Molecular Weight
| 13458.6 |
Theoretical pI
| 5.81 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
MAGVLKKTTGLVGLAVCNTPHERLRILYTKILDVLEEIPKNAAYRKYTEQITNEKLAMVK
AEPDVKKLEDQLQGGQLEEVILQAEHELNLARKMREWKLWEPLVEEPPADQWKWPI
|
External Links |
GenBank ID Protein
| 37674403 |
UniProtKB/Swiss-Prot ID
| Q16718 |
UniProtKB/Swiss-Prot Entry Name
| NDUA5_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AC073323 |
GeneCard ID
| NDUFA5 |
GenAtlas ID
| NDUFA5 |
HGNC ID
| HGNC:7688 |
References |
General References
| Not Available |