Identification |
HMDB Protein ID
| CDBP02509 |
Secondary Accession Numbers
| Not Available |
Name
| Probable saccharopine dehydrogenase |
Description
| Not Available |
Synonyms
|
Not Available
|
Gene Name
| SCCPDH |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in catalytic activity |
Specific Function
| N(6)-(L-1,3-dicarboxypropyl)-L-lysine + NAD(+) + H(2)O = L-glutamate + 2-aminoadipate 6-semialdehyde + NADH |
GO Classification
|
Function |
binding |
catalytic activity |
Process |
metabolic process |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 1q44 |
SNPs
| SCCPDH |
Gene Sequence
|
>1290 bp
ATGGCGACCGAGCAGAGGCCTTTCCACCTGGTGGTGTTCGGCGCGTCTGGCTTCACCGGC
CAGTTCGTGACCGAGGAGGTGGCCCGGGAGCAGGTGGACCCGGAGCGGAGCTCCCGCCTG
CCCTGGGCCGTGGCGGGCCGCTCCCGGGAGAAGCTGCAGCGGGTGCTGGAGAAGGCGGCC
CTGAAGCTGGGAAGACCAACACTGTCATCTGAAGTTGGAATCATCATCTGTGATATTGCT
AATCCAGCCTCGCTTGATGAAATGGCTAAACAGGCAACAGTTGTCCTCAATTGCGTAGGA
CCATATCGGTTTTATGGAGAACCTGTAATAAAAGCATGTATTGAAAATGGAGCCAGTTGT
ATCGACATCAGTGGAGAACCTCAGTTTCTGGAACTAATGCAACTGAAGTATCATGAGAAA
GCTGCAGACAAAGGGGTTTATATCATTGGAAGCAGCGGCTTTGACTCCATTCCAGCAGAT
CTGGGAGTAATATATACCAGAAATAAAATGAATGGTACTTTGACTGCTGTGGAAAGTTTC
CTGACTATACATTCAGGACCTGAGGGGTTGAGCATTCATGATGGTACCTGGAAGTCAGCA
ATTTATGGTTTTGGAGATCAGAGTAATTTGAGAAAACTAAGAAATGTATCAAATCTGAAA
CCTGTCCCGCTCATTGGTCCAAAATTGAAGAGAAGGTGGCCAATTTCTTATTGTCGGGAA
CTCAAAGGTTATTCCATTCCTTTTATGGGATCTGATGTGTCTGTTGTAAGGAGGACTCAA
CGTTACTTGTATGAAAATTTAGAGGAATCACCAGTTCAGTATGCTGCGTATGTAACTGTG
GGAGGCATCACCTCTGTTATTAAGCTGATGTTTGCAGGACTTTTCTTTTTGTTCTTTGTG
AGGTTTGGAATTGGAAGGCAACTTCTCATAAAATTCCCATGGTTCTTCTCCTTTGGCTAT
TTTTCAAAACAAGGCCCAACACAAAAACAGATTGATGCTGCCTCATTCACGCTGACATTC
TTTGGTCAAGGATACAGCCAAGGCACTGGTACAGATAAGAACAAACCAAATATCAAAATT
TGTACTCAGGTGAAAGGACCAGAGGCTGGCTATGTGGCTACCCCCATAGCTATGGTTCAG
GCAGCCATGACTCTTCTAAGTGATGCTTCTCATCTGCCTAAGGCGGGCGGGGTCTTCACA
CCTGGAGCAGCTTTTTCCAAAACAAAGTTGATTGACAGACTCAACAAACACGGTATTGAG
TTTAGTGTTATTAGCAGCTCTGAAGTCTAA
|
Protein Properties |
Number of Residues
| 429 |
Molecular Weight
| 47151.0 |
Theoretical pI
| 9.53 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Probable saccharopine dehydrogenase
MATEQRPFHLVVFGASGFTGQFVTEEVAREQVDPERSSRLPWAVAGRSREKLQRVLEKAA
LKLGRPTLSSEVGIIICDIANPASLDEMAKQATVVLNCVGPYRFYGEPVIKACIENGASC
IDISGEPQFLELMQLKYHEKAADKGVYIIGSSGFDSIPADLGVIYTRNKMNGTLTAVESF
LTIHSGPEGLSIHDGTWKSAIYGFGDQSNLRKLRNVSNLKPVPLIGPKLKRRWPISYCRE
LKGYSIPFMGSDVSVVRRTQRYLYENLEESPVQYAAYVTVGGITSVIKLMFAGLFFLFFV
RFGIGRQLLIKFPWFFSFGYFSKQGPTQKQIDAASFTLTFFGQGYSQGTGTDKNKPNIKI
CTQVKGPEAGYVATPIAMVQAAMTLLSDASHLPKAGGVFTPGAAFSKTKLIDRLNKHGIE
FSVISSSEV
|
External Links |
GenBank ID Protein
| 55770836 |
UniProtKB/Swiss-Prot ID
| Q8NBX0 |
UniProtKB/Swiss-Prot Entry Name
| SCPDH_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_016002.2 |
GeneCard ID
| SCCPDH |
GenAtlas ID
| SCCPDH |
HGNC ID
| HGNC:24275 |
References |
General References
| Not Available |