Identification
HMDB Protein ID CDBP02509
Secondary Accession Numbers Not Available
Name Probable saccharopine dehydrogenase
Description Not Available
Synonyms Not Available
Gene Name SCCPDH
Protein Type Enzyme
Biological Properties
General Function Involved in catalytic activity
Specific Function N(6)-(L-1,3-dicarboxypropyl)-L-lysine + NAD(+) + H(2)O = L-glutamate + 2-aminoadipate 6-semialdehyde + NADH
GO Classification
Function
binding
catalytic activity
Process
metabolic process
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 1q44
SNPs SCCPDH
Gene Sequence
>1290 bp
ATGGCGACCGAGCAGAGGCCTTTCCACCTGGTGGTGTTCGGCGCGTCTGGCTTCACCGGC
CAGTTCGTGACCGAGGAGGTGGCCCGGGAGCAGGTGGACCCGGAGCGGAGCTCCCGCCTG
CCCTGGGCCGTGGCGGGCCGCTCCCGGGAGAAGCTGCAGCGGGTGCTGGAGAAGGCGGCC
CTGAAGCTGGGAAGACCAACACTGTCATCTGAAGTTGGAATCATCATCTGTGATATTGCT
AATCCAGCCTCGCTTGATGAAATGGCTAAACAGGCAACAGTTGTCCTCAATTGCGTAGGA
CCATATCGGTTTTATGGAGAACCTGTAATAAAAGCATGTATTGAAAATGGAGCCAGTTGT
ATCGACATCAGTGGAGAACCTCAGTTTCTGGAACTAATGCAACTGAAGTATCATGAGAAA
GCTGCAGACAAAGGGGTTTATATCATTGGAAGCAGCGGCTTTGACTCCATTCCAGCAGAT
CTGGGAGTAATATATACCAGAAATAAAATGAATGGTACTTTGACTGCTGTGGAAAGTTTC
CTGACTATACATTCAGGACCTGAGGGGTTGAGCATTCATGATGGTACCTGGAAGTCAGCA
ATTTATGGTTTTGGAGATCAGAGTAATTTGAGAAAACTAAGAAATGTATCAAATCTGAAA
CCTGTCCCGCTCATTGGTCCAAAATTGAAGAGAAGGTGGCCAATTTCTTATTGTCGGGAA
CTCAAAGGTTATTCCATTCCTTTTATGGGATCTGATGTGTCTGTTGTAAGGAGGACTCAA
CGTTACTTGTATGAAAATTTAGAGGAATCACCAGTTCAGTATGCTGCGTATGTAACTGTG
GGAGGCATCACCTCTGTTATTAAGCTGATGTTTGCAGGACTTTTCTTTTTGTTCTTTGTG
AGGTTTGGAATTGGAAGGCAACTTCTCATAAAATTCCCATGGTTCTTCTCCTTTGGCTAT
TTTTCAAAACAAGGCCCAACACAAAAACAGATTGATGCTGCCTCATTCACGCTGACATTC
TTTGGTCAAGGATACAGCCAAGGCACTGGTACAGATAAGAACAAACCAAATATCAAAATT
TGTACTCAGGTGAAAGGACCAGAGGCTGGCTATGTGGCTACCCCCATAGCTATGGTTCAG
GCAGCCATGACTCTTCTAAGTGATGCTTCTCATCTGCCTAAGGCGGGCGGGGTCTTCACA
CCTGGAGCAGCTTTTTCCAAAACAAAGTTGATTGACAGACTCAACAAACACGGTATTGAG
TTTAGTGTTATTAGCAGCTCTGAAGTCTAA
Protein Properties
Number of Residues 429
Molecular Weight 47151.0
Theoretical pI 9.53
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Probable saccharopine dehydrogenase
MATEQRPFHLVVFGASGFTGQFVTEEVAREQVDPERSSRLPWAVAGRSREKLQRVLEKAA
LKLGRPTLSSEVGIIICDIANPASLDEMAKQATVVLNCVGPYRFYGEPVIKACIENGASC
IDISGEPQFLELMQLKYHEKAADKGVYIIGSSGFDSIPADLGVIYTRNKMNGTLTAVESF
LTIHSGPEGLSIHDGTWKSAIYGFGDQSNLRKLRNVSNLKPVPLIGPKLKRRWPISYCRE
LKGYSIPFMGSDVSVVRRTQRYLYENLEESPVQYAAYVTVGGITSVIKLMFAGLFFLFFV
RFGIGRQLLIKFPWFFSFGYFSKQGPTQKQIDAASFTLTFFGQGYSQGTGTDKNKPNIKI
CTQVKGPEAGYVATPIAMVQAAMTLLSDASHLPKAGGVFTPGAAFSKTKLIDRLNKHGIE
FSVISSSEV
GenBank ID Protein 55770836
UniProtKB/Swiss-Prot ID Q8NBX0
UniProtKB/Swiss-Prot Entry Name SCPDH_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_016002.2
GeneCard ID SCCPDH
GenAtlas ID SCCPDH
HGNC ID HGNC:24275
References
General References Not Available