Identification |
HMDB Protein ID
| CDBP00257 |
Secondary Accession Numbers
| Not Available |
Name
| Methylsterol monooxygenase 1 |
Description
| Not Available |
Synonyms
|
- Methylsterol monooxygenase
- SubName: cDNA FLJ50771, highly similar to C-4 methylsterol oxidase (EC 1.14.13.72)
- C-4 methylsterol oxidase
|
Gene Name
| MSMO1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in iron ion binding |
Specific Function
| Not Available |
GO Classification
|
Biological Process |
fatty acid biosynthetic process |
cholesterol biosynthetic process |
fatty acid metabolic process |
Cellular Component |
endoplasmic reticulum membrane |
plasma membrane |
integral to membrane |
Component |
endoplasmic reticulum |
organelle |
membrane-bounded organelle |
intracellular membrane-bounded organelle |
Function |
ion binding |
cation binding |
metal ion binding |
binding |
catalytic activity |
transition metal ion binding |
iron ion binding |
oxidoreductase activity |
Molecular Function |
C-4 methylsterol oxidase activity |
iron ion binding |
Process |
metabolic process |
cellular metabolic process |
organic acid metabolic process |
oxoacid metabolic process |
carboxylic acid metabolic process |
monocarboxylic acid metabolic process |
fatty acid metabolic process |
fatty acid biosynthetic process |
oxidation reduction |
|
Cellular Location
|
- Endoplasmic reticulum membrane
- Multi-pass membrane protein (Probable)
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | zymosterol biosynthesis | Not Available | Not Available | Steroid Biosynthesis | | | Smith-Lemli-Opitz Syndrome (SLOS) | | Not Available | CHILD Syndrome | | Not Available | Desmosterolosis | | Not Available |
|
Gene Properties |
Chromosome Location
| 4 |
Locus
| 4q32-q34 |
SNPs
| SC4MOL |
Gene Sequence
|
>882 bp
ATGGCAACAAATGAAAGTGTCAGCATCTTTAGTTCAGCATCCTTGGCTGTGGAATATGTA
GATTCACTTTTACCTGAGAATCCTCTGCAAGAACCATTTAAAAATGCTTGGAACTATATG
TTGAATAATTATACAAAGTTCCAGATTGCAACATGGGGATCCCTTATAGTTCATGAAGCC
CTTTATTTCTTATTCTGTTTACCTGGATTTTTATTTCAATTTATACCTTATATGAAAAAA
TACAAAATTCAAAAGGATAAGCCAGAGACATGGGAAAACCAATGGAAGTGTTTCAAAGTT
CTTCTCTTTAATCACTTCTGTATCCAGCTGCCTTTGATTTGTGGAACCTATTATTTTACA
GAGTATTTCAATATTCCTTATGATTGGGAAAGAATGCCAAGATGGTATTTTCTTTTGGCA
AGATGCTTTGGTTGTGCAGTCATTGAAGATACTTGGCACTATTTTCTGCATAGACTCTTA
CACCACAAAAGAATATACAAGTATATTCATAAAGTTCATCATGAGTTTCAGGCTCCATTT
GGAATGGAAGCTGAATATGCACATCCTTTGGAGACTCTAATTCTTGGAACTGGATTTTTC
ATTGGAATCGTGCTTTTGTGTGATCATGTAATTCTTCTTTGGGCATGGGTGACCATTCGT
TTATTAGAAACTATTGATGTCCATAGTGGTTATGATATTCCTCTCAACCCTTTAAATCTG
ATCCCTTTCTATGCTGGTTCTCGGCATCATGATTTCCACCACATGAACTTCATTGGAAAC
TATGCTTCAACATTTACATGGTGGGATCGAATTTTTGGAACAGACTCTCAGTATAATGCC
TATAATGAAAAGAGGAAGAAGTTTGAGAAAAAGACTGAATAA
|
Protein Properties |
Number of Residues
| 293 |
Molecular Weight
| 19470.325 |
Theoretical pI
| 7.701 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>C-4 methylsterol oxidase
MATNESVSIFSSASLAVEYVDSLLPENPLQEPFKNAWNYMLNNYTKFQIATWGSLIVHEA
LYFLFCLPGFLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFT
EYFNIPYDWERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPF
GMEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNL
IPFYAGSRHHDFHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE
|
External Links |
GenBank ID Protein
| 62865628 |
UniProtKB/Swiss-Prot ID
| Q15800 |
UniProtKB/Swiss-Prot Entry Name
| ERG25_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| U60205 |
GeneCard ID
| SC4MOL |
GenAtlas ID
| SC4MOL |
HGNC ID
| HGNC:10545 |
References |
General References
| Not Available |