Showing Compound Card for Hydrogen Ion (CDB005054)

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Record Information
Version1.0
Created at2020-04-17 19:04:40 UTC
Updated at2020-11-18 16:39:15 UTC
CannabisDB IDCDB005054
Secondary Accession NumbersNot Available
Cannabis Compound Identification
Common NameHydrogen Ion
DescriptionHydrogen Ion, also known as H+ or hydron, belongs to the class of inorganic compounds known as other non-metal hydrides. These are inorganic compounds in which the heaviest atom bonded to a hydrogen atom is belongs to the class of 'other non-metals'. Under aqueous conditions found in biochemistry, hydrogen ions exist as the hydrated form hydronium, H3O+, but these are often still referred to as hydrogen ions or even protons by biochemists. Hydrogen ion is recommended by IUPAC as a general term for all ions of hydrogen and its isotopes. Hydrogen Ion is possibly neutral. Outside of the human body, Hydrogen Ion has been detected, but not quantified in, several different foods, such as sourdoughs, common grapes, lemon thymes, rowals, and sweet basils. This could make hydrogen ion a potential biomarker for the consumption of these foods. Depending on the charge of the ion, two different classes can be distinguished: positively charged ions and negatively charged ions. Hydrogen Ion is expected to be in Cannabis as all living plants are known to produce and metabolize it.
Structure
Thumb
MOLSDFPDBSMILESInChI
Synonyms
ValueSource
H+ChEBI
H(+)ChEBI
HydronKegg
Hydrogen cationHMDB
ProtonHMDB
ProtonsMeSH
Hydrogen ionsMeSH
Ions, hydrogenMeSH
Ion, hydrogenMeSH
Chemical FormulaH
Average Molecular Weight1.01
Monoisotopic Molecular Weight1.0078
IUPAC Namehydron
Traditional Namehydron
CAS Registry NumberNot Available
SMILES
[H+]
InChI Identifier
InChI=1S/p+1
InChI KeyGPRLSGONYQIRFK-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of inorganic compounds known as other non-metal hydrides. These are inorganic compounds in which the heaviest atom bonded to a hydrogen atom is belongs to the class of 'other non-metals'.
KingdomInorganic compounds
Super ClassHomogeneous non-metal compounds
ClassOther non-metal organides
Sub ClassOther non-metal hydrides
Direct ParentOther non-metal hydrides
Alternative ParentsNot Available
Substituents
  • Other non-metal hydride
Molecular FrameworkNot Available
External Descriptors
Ontology
Not Available
Physical Properties
StateSolid
Experimental Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
logPNot AvailableNot Available
Predicted Properties
PropertyValueSource
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 ŲChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m³·mol⁻¹ChemAxon
Polarizability0.52 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityYesChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Spectra
EI-MS/GC-MSNot Available
MS/MS
TypeDescriptionSplash KeyView
Predicted MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-0udi-9000000000-1d1de5a5c37fe86ebc2f2015-09-15View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-0udi-9000000000-1d1de5a5c37fe86ebc2f2015-09-15View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0udi-9000000000-1d1de5a5c37fe86ebc2f2015-09-15View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-0udi-9000000000-cb753f988e32a89d6a3a2015-09-15View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-0udi-9000000000-cb753f988e32a89d6a3a2015-09-15View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-0udi-9000000000-cb753f988e32a89d6a3a2015-09-15View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-0udi-9000000000-b9f405991be2f21d47362021-09-22View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-0udi-9000000000-b9f405991be2f21d47362021-09-22View Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-0udi-9000000000-b9f405991be2f21d47362021-09-22View Spectrum
NMRNot Available
Pathways
Pathways
Protein Targets
Enzymes
Protein NameGene NameLocusUniprot IDDetails
Fatty acid synthaseFASN17q25P49327 details
Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrialALDH6A114q24.3Q02252 details
Dihydrolipoyl dehydrogenase, mitochondrialDLD7q31-q32P09622 details
Aldo-keto reductase family 1 member C4AKR1C410p15.1P17516 details
Carbonyl reductase [NADPH] 1CBR121q22.13P16152 details
Carbonyl reductase [NADPH] 3CBR321q22.2O75828 details
TyrosinaseTYR11q14-q21P14679 details
Aldose reductaseAKR1B17q35P15121 details
Short-chain specific acyl-CoA dehydrogenase, mitochondrialACADS12q24.31P16219 details
NADH-cytochrome b5 reductase 3CYB5R322q13.2P00387 details
Aldehyde oxidaseAOX12q33Q06278 details
Thioredoxin reductase 1, cytoplasmicTXNRD112q23-q24.1Q16881 details
Lathosterol oxidaseSC5DL11q23.3O75845 details
Dimethylaniline monooxygenase [N-oxide-forming] 5FMO51q21.1P49326 details
Squalene monooxygenaseSQLE8q24.1Q14534 details
Dimethylaniline monooxygenase [N-oxide-forming] 2FMO21q24.3Q99518 details
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrialALDH4A11p36P30038 details
Thioredoxin reductase 2, mitochondrialTXNRD222q11.21Q9NNW7 details
Dimethylaniline monooxygenase [N-oxide-forming] 4FMO41q24.3P31512 details
Dimethylaniline monooxygenase [N-oxide-forming] 3FMO31q24.3P31513 details
Xanthine dehydrogenase/oxidaseXDH2p23.1P47989 details
Dimethylaniline monooxygenase [N-oxide-forming] 1FMO11q24.3Q01740 details
Methylenetetrahydrofolate reductaseMTHFR1p36.3P42898 details
Glutathione reductase, mitochondrialGSR8p21.1P00390 details
Retinal dehydrogenase 1ALDH1A19q21.13P00352 details
NADPH:adrenodoxin oxidoreductase, mitochondrialFDXR17q24-q25P22570 details
Retinal dehydrogenase 2ALDH1A215q21.3O94788 details
Succinate-semialdehyde dehydrogenase, mitochondrialALDH5A16p22P51649 details
Coproporphyrinogen-III oxidase, mitochondrialCPOX3q12P36551 details
Squalene synthaseFDFT18p23.1-p22P37268 details
Delta(14)-sterol reductaseTM7SF211q13O76062 details
Methylsterol monooxygenase 1MSMO14q32-q34Q15800 details
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylatingNSDHLXq28Q15738 details
Lanosterol 14-alpha demethylaseCYP51A17q21.2Q16850 details
Thyroid peroxidaseTPO2p25P07202 details
MyeloperoxidaseMPO17q23.1P05164 details
4-trimethylaminobutyraldehyde dehydrogenaseALDH9A11q23.1P49189 details
Aldehyde dehydrogenase, dimeric NADP-preferringALDH3A117p11.2P30838 details
Alpha-aminoadipic semialdehyde dehydrogenaseALDH7A15q31P49419 details
Aldehyde dehydrogenase family 1 member A3ALDH1A315q26.3P47895 details
Aldehyde dehydrogenase, mitochondrialALDH212q24.2P05091 details
Fatty aldehyde dehydrogenaseALDH3A217p11.2P51648 details
Aldehyde dehydrogenase X, mitochondrialALDH1B19p11.1P30837 details
Pyrroline-5-carboxylate reductase 1, mitochondrialPYCR117q25.3P32322 details
Pyrroline-5-carboxylate reductase 2PYCR21q42.12Q96C36 details
L-xylulose reductaseDCXR17q25.3Q7Z4W1 details
Acyl-CoA desaturaseSCD10q24.31O00767 details
Glucose-6-phosphate 1-dehydrogenaseG6PDXq28P11413 details
Aldo-keto reductase family 1 member C3AKR1C310p15-p14P42330 details
3-hydroxyacyl-CoA dehydrogenase type-2HSD17B10Xp11.2Q99714 details
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrialHADH4q22-q26Q16836 details
Aldo-keto reductase family 1 member C1AKR1C110p15-p14Q04828 details
Aldo-keto reductase family 1 member C2AKR1C210p15-p14P52895 details
Glyoxylate reductase/hydroxypyruvate reductaseGRHPR9q12Q9UBQ7 details
Membrane primary amine oxidaseAOC317q21Q16853 details
Retina-specific copper amine oxidaseAOC217q21O75106 details
3-hydroxyisobutyrate dehydrogenase, mitochondrialHIBADH7p15.2P31937 details
Hexaprenyldihydroxybenzoate methyltransferase, mitochondrialCOQ36q16.2Q9NZJ6 details
S-adenosylmethionine decarboxylase proenzymeAMD16q21P17707 details
Nicotinamide N-methyltransferaseNNMT11q23.1P40261 details
Sepiapterin reductaseSPR2p14-p12P35270 details
2-oxoglutarate dehydrogenase, mitochondrialOGDH7p14-p13Q02218 details
Estradiol 17-beta-dehydrogenase 2HSD17B216q24.1-q24.2P37059 details
Estradiol 17-beta-dehydrogenase 8HSD17B86p21.3Q92506 details
Trans-1,2-dihydrobenzene-1,2-diol dehydrogenaseDHDH19q13.3Q9UQ10 details
Cholesterol 7-alpha-monooxygenaseCYP7A18q11-q12P22680 details
Sorbitol dehydrogenaseSORD15q15.3Q00796 details
Alcohol dehydrogenase [NADP(+)]AKR1A11p33-p32P14550 details
Alcohol dehydrogenase 4ADH44q22P08319 details
D-beta-hydroxybutyrate dehydrogenase, mitochondrialBDH13q29Q02338 details
Aldehyde dehydrogenase family 3 member B2ALDH3B211q13P48448 details
Aldehyde dehydrogenase family 3 member B1ALDH3B111q13P43353 details
Dihydropteridine reductaseQDPR4p15.31P09417 details
7-dehydrocholesterol reductaseDHCR711q13.4Q9UBM7 details
3-oxo-5-beta-steroid 4-dehydrogenaseAKR1D17q32-q33P51857 details
Glutamate dehydrogenase 2, mitochondrialGLUD2Xq24-q25P49448 details
GMP reductase 2GMPR214q12Q9P2T1 details
GMP reductase 1GMPR6p23P36959 details
Formimidoyltransferase-cyclodeaminaseFTCD21q22.3O95954 details
Aminomethyltransferase, mitochondrialAMT3p21.2-p21.1P48728 details
Glyceraldehyde-3-phosphate dehydrogenase, testis-specificGAPDHS19q13.12O14556 details
Glutamate dehydrogenase 1, mitochondrialGLUD110q23.3P00367 details
Glyceraldehyde-3-phosphate dehydrogenaseGAPDH12p13P04406 details
Biliverdin reductase ABLVRA7p13P53004 details
Flavin reductase (NADPH)BLVRB19q13.1-q13.2P30043 details
Corticosteroid 11-beta-dehydrogenase isozyme 1HSD11B11q32-q41P28845 details
Dihydropyrimidine dehydrogenase [NADP(+)]DPYD1p22Q12882 details
Alcohol dehydrogenase class-3ADH54q23P11766 details
Alcohol dehydrogenase 1BADH1B4q23P00325 details
Alcohol dehydrogenase class 4 mu/sigma chainADH74q23-q24P40394 details
Alcohol dehydrogenase 1AADH1A4q23P07327 details
Alcohol dehydrogenase 6ADH64q23P28332 details
Alcohol dehydrogenase 1CADH1C4q23P00326 details
Dihydrofolate reductaseDHFR5q11.2-q13.2P00374 details
Glutathione S-transferase Mu 2GSTM21p13.3P28161 details
Glutathione S-transferase Mu 1GSTM11p13.3P09488 details
Glutathione S-transferase kappa 1GSTK17q34Q9Y2Q3 details
Microsomal glutathione S-transferase 3MGST31q23O14880 details
Glutathione S-transferase Mu 3GSTM31p13.3P21266 details
Glutathione S-transferase A1GSTA16p12.1P08263 details
Microsomal glutathione S-transferase 1MGST112p12.3-p12.1P10620 details
Glutathione S-transferase Mu 4GSTM41p13.3Q03013 details
Glutathione S-transferase Mu 5GSTM51p13.3P46439 details
Microsomal glutathione S-transferase 2MGST24q28.3Q99735 details
Glutathione S-transferase omega-1GSTO110q25.1P78417 details
Glutathione S-transferase A5GSTA56p12.2Q7RTV2 details
Glutathione S-transferase A2GSTA26p12.1P09210 details
Glutathione S-transferase A3GSTA36p12.1Q16772 details
Glutathione S-transferase A4GSTA46p12.1O15217 details
Glutathione S-transferase omega-2GSTO210q25.1Q9H4Y5 details
Glutathione S-transferase theta-1GSTT122q11.23P30711 details
Glutathione S-transferase PGSTP111q13P09211 details
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmicGPD112q12-q13P21695 details
Testosterone 17-beta-dehydrogenase 3HSD17B39q22P37058 details
Estradiol 17-beta-dehydrogenase 1HSD17B117q11-q21P14061 details
3-keto-steroid reductaseHSD17B71q23P56937 details
Alpha-aminoadipic semialdehyde synthase, mitochondrialAASS7q31.3Q9UDR5 details
Delta-1-pyrroline-5-carboxylate synthaseALDH18A110q24.3P54886 details
Malate dehydrogenase, mitochondrialMDH27cen-q22P40926 details
Malate dehydrogenase, cytoplasmicMDH12p13.3P40925 details
Inosine-5'-monophosphate dehydrogenase 2IMPDH23p21.2P12268 details
Inosine-5'-monophosphate dehydrogenase 1IMPDH17q31.3-q32P20839 details
L-lactate dehydrogenase A-like 6ALDHAL6A11p15.1Q6ZMR3 details
Isocitrate dehydrogenase [NADP], mitochondrialIDH215q26.1P48735 details
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrialIDH3B20p13O43837 details
Isocitrate dehydrogenase [NADP] cytoplasmicIDH12q33.3O75874 details
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrialIDH3A15q25.1-q25.2P50213 details
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrialIDH3GXq28P51553 details
UDP-glucose 6-dehydrogenaseUGDH4p15.1O60701 details
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHMGCR5q13.3-q14P04035 details
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrialMTHFD22p13.1P13995 details
D-3-phosphoglycerate dehydrogenasePHGDH1p12O43175 details
C-1-tetrahydrofolate synthase, cytoplasmicMTHFD114q24P11586 details
GDP-L-fucose synthaseTSTA38q24.3Q13630 details
Nitric oxide synthase, inducibleNOS217q11.2-q12P35228 details
Nitric oxide synthase, brainNOS112q24.2-q24.31P29475 details
Nitric oxide synthase, endothelialNOS37q36P29474 details
Cytosolic 10-formyltetrahydrofolate dehydrogenaseALDH1L13q21.3O75891 details
Cytochrome b-c1 complex subunit Rieske, mitochondrialUQCRFS119q12P47985 details
Trans-2-enoyl-CoA reductase, mitochondrialMECR1p35.3Q9BV79 details
Peroxisomal trans-2-enoyl-CoA reductasePECR2q35Q9BY49 details
Leukotriene-B(4) omega-hydroxylase 1CYP4F219p13.12P78329 details
Leukotriene-B(4) omega-hydroxylase 2CYP4F319p13.2Q08477 details
Sterol 26-hydroxylase, mitochondrialCYP27A12q33-qterQ02318 details
6-phosphogluconate dehydrogenase, decarboxylatingPGD1p36.22P52209 details
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialCYP27B112q13.1-q13.3O15528 details
Steroid 17-alpha-hydroxylase/17,20 lyaseCYP17A110q24.3P05093 details
Ferrochelatase, mitochondrialFECH18q21.3P22830 details
Type I iodothyronine deiodinaseDIO11p33-p32P49895 details
Type II iodothyronine deiodinaseDIO214q24.2-q24.3Q92813 details
5-formyltetrahydrofolate cyclo-ligaseMTHFS15q25.1P49914 details
CatalaseCAT11p13P04040 details
Short/branched chain specific acyl-CoA dehydrogenase, mitochondrialACADSB10q26.13P45954 details
25-hydroxycholesterol 7-alpha-hydroxylaseCYP7B18q21.3O75881 details
Cytochrome c oxidase subunit 1MT-CO1P00395 details
NAD(P)H dehydrogenase [quinone] 1NQO116q22.1P15559 details
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialCYP24A120q13Q07973 details
Delta(24)-sterol reductaseDHCR241p32.3Q15392 details
Superoxide dismutase [Mn], mitochondrialSOD26q25.3P04179 details
Proline dehydrogenase 1, mitochondrialPRODH22q11.21O43272 details
Superoxide dismutase [Cu-Zn]SOD121q22.11P00441 details
Kynurenine 3-monooxygenaseKMO1q42-q44O15229 details
Vitamin D 25-hydroxylaseCYP2R111p15.2Q6VVX0 details
17-beta-hydroxysteroid dehydrogenase type 6HSD17B612q13O14756 details
Pyrroline-5-carboxylate reductase 3PYCRL8q24.3Q53H96 details
3-ketodihydrosphingosine reductaseKDSR18q21.3Q06136 details
Glycine cleavage system H protein, mitochondrialGCSHP23434 details
Extracellular superoxide dismutase [Cu-Zn]SOD34p15.2P08294 details
L-lactate dehydrogenase B chainLDHB12p12.2-p12.1P07195 details
L-lactate dehydrogenase C chainLDHC11p15.1P07864 details
L-lactate dehydrogenase A chainLDHA11p15.4P00338 details
L-lactate dehydrogenase A-like 6BLDHAL6B15q22.2Q9BYZ2 details
Probable D-lactate dehydrogenase, mitochondrialLDHD16q23.1Q86WU2 details
Purine nucleoside phosphorylasePNP14q13.1P00491 details
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1HSD3B11p13.1P14060 details
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2HSD3B21p13.1P26439 details
3 beta-hydroxysteroid dehydrogenase type 7HSD3B716p11.2Q9H2F3 details
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylaseCYP8B13p22.1Q9UNU6 details
Thioredoxin reductase 3TXNRD33q21.3Q86VQ6 details
3-hydroxybutyrate dehydrogenase type 2BDH24q24Q9BUT1 details
Glycerol-3-phosphate dehydrogenase 1-like proteinGPD1L3p22.3Q8N335 details
Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2MTHFD2L4q13.3Q9H903 details
NADH-cytochrome b5 reductase 1CYB5R11q32.1Q9UHQ9 details
NADH-cytochrome b5 reductase 2CYB5R211p15.4Q6BCY4 details
Cytochrome b5 reductase 4CYB5R46pter-q22.33Q7L1T6 details
NADH-cytochrome b5 reductase-likeCYB5RL1p32.3Q6IPT4 details
Mitochondrial 10-formyltetrahydrofolate dehydrogenaseALDH1L212q23.3Q3SY69 details
Stearoyl-CoA desaturase 5SCD54q21.22Q86SK9 details
Probable imidazolonepropionaseAMDHD112q23.1Q96NU7 details
Estradiol 17-beta-dehydrogenase 12HSD17B1211p11.2Q53GQ0 details
Molybdenum cofactor sulfuraseMOCOS18q12Q96EN8 details
2-oxoglutarate dehydrogenase-like, mitochondrialOGDHLQ9ULD0 details
Type III iodothyronine deiodinaseDIO314q32P55073 details
Aldo-keto reductase family 1 member B10AKR1B10O60218 details
Steroid 21-hydroxylaseCYP21A26p21.3P08686 details
Dihydrofolate reductase, mitochondrialDHFRL13q11.1Q86XF0 details
Glutathione S-transferase theta-2BGSTT2B22q11.23P0CG30 details
Epidermal retinol dehydrogenase 2SDR16C58q12.1Q8N3Y7 details
Transporters
Protein NameGene NameLocusUniprot IDDetails
Fatty acid synthaseFASN17q25P49327 details
Aldo-keto reductase family 1 member C4AKR1C410p15.1P17516 details
Nitric oxide synthase, inducibleNOS217q11.2-q12P35228 details
Cytosolic 10-formyltetrahydrofolate dehydrogenaseALDH1L13q21.3O75891 details
Cytochrome b-c1 complex subunit Rieske, mitochondrialUQCRFS119q12P47985 details
Glycerol-3-phosphate dehydrogenase 1-like proteinGPD1L3p22.3Q8N335 details
Mitochondrial 10-formyltetrahydrofolate dehydrogenaseALDH1L212q23.3Q3SY69 details
Metal Bindings
Protein NameGene NameLocusUniprot IDDetails
Fatty acid synthaseFASN17q25P49327 details
Aldehyde oxidaseAOX12q33Q06278 details
Lathosterol oxidaseSC5DL11q23.3O75845 details
Xanthine dehydrogenase/oxidaseXDH2p23.1P47989 details
Methylsterol monooxygenase 1MSMO14q32-q34Q15800 details
Lanosterol 14-alpha demethylaseCYP51A17q21.2Q16850 details
Thyroid peroxidaseTPO2p25P07202 details
MyeloperoxidaseMPO17q23.1P05164 details
Acyl-CoA desaturaseSCD10q24.31O00767 details
Membrane primary amine oxidaseAOC317q21Q16853 details
Retina-specific copper amine oxidaseAOC217q21O75106 details
Cytochrome P450 4A11CYP4A111p33Q02928 details
Ferritin, mitochondrialFTMT5q21.3Q8N4E7 details
CeruloplasminCP3q23-q25P00450 details
Cholesterol 7-alpha-monooxygenaseCYP7A18q11-q12P22680 details
Sorbitol dehydrogenaseSORD15q15.3Q00796 details
Alcohol dehydrogenase 4ADH44q22P08319 details
GMP reductase 2GMPR214q12Q9P2T1 details
GMP reductase 1GMPR6p23P36959 details
Biliverdin reductase ABLVRA7p13P53004 details
Cholesterol side-chain cleavage enzyme, mitochondrialCYP11A115q23-q24P05108 details
Dihydropyrimidine dehydrogenase [NADP(+)]DPYD1p22Q12882 details
Alcohol dehydrogenase class-3ADH54q23P11766 details
Alcohol dehydrogenase 1BADH1B4q23P00325 details
Alcohol dehydrogenase class 4 mu/sigma chainADH74q23-q24P40394 details
Alcohol dehydrogenase 1AADH1A4q23P07327 details
Alcohol dehydrogenase 6ADH64q23P28332 details
Alcohol dehydrogenase 1CADH1C4q23P00326 details
NADP-dependent malic enzymeME16q12P48163 details
NADP-dependent malic enzyme, mitochondrialME311cen-q22.3Q16798 details
NAD-dependent malic enzyme, mitochondrialME218q21P23368 details
Inosine-5'-monophosphate dehydrogenase 2IMPDH23p21.2P12268 details
Inosine-5'-monophosphate dehydrogenase 1IMPDH17q31.3-q32P20839 details
Isocitrate dehydrogenase [NADP], mitochondrialIDH215q26.1P48735 details
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrialIDH3B20p13O43837 details
Isocitrate dehydrogenase [NADP] cytoplasmicIDH12q33.3O75874 details
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrialIDH3A15q25.1-q25.2P50213 details
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrialIDH3GXq28P51553 details
Nitric oxide synthase, inducibleNOS217q11.2-q12P35228 details
Nitric oxide synthase, brainNOS112q24.2-q24.31P29475 details
Nitric oxide synthase, endothelialNOS37q36P29474 details
Cytochrome b-c1 complex subunit Rieske, mitochondrialUQCRFS119q12P47985 details
Trans-2-enoyl-CoA reductase, mitochondrialMECR1p35.3Q9BV79 details
Leukotriene-B(4) omega-hydroxylase 1CYP4F219p13.12P78329 details
Leukotriene-B(4) omega-hydroxylase 2CYP4F319p13.2Q08477 details
Sterol 26-hydroxylase, mitochondrialCYP27A12q33-qterQ02318 details
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialCYP27B112q13.1-q13.3O15528 details
Steroid 17-alpha-hydroxylase/17,20 lyaseCYP17A110q24.3P05093 details
Cytochrome P450 4F11CYP4F1119p13.1Q9HBI6 details
Cytochrome P450 4F8CYP4F819p13.1P98187 details
CatalaseCAT11p13P04040 details
25-hydroxycholesterol 7-alpha-hydroxylaseCYP7B18q21.3O75881 details
Cytochrome c oxidase subunit 1MT-CO1P00395 details
Ubiquinone biosynthesis protein COQ7 homologCOQ7Q99807 details
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialCYP24A120q13Q07973 details
Superoxide dismutase [Mn], mitochondrialSOD26q25.3P04179 details
Superoxide dismutase [Cu-Zn]SOD121q22.11P00441 details
Vitamin D 25-hydroxylaseCYP2R111p15.2Q6VVX0 details
Extracellular superoxide dismutase [Cu-Zn]SOD34p15.2P08294 details
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylaseCYP8B13p22.1Q9UNU6 details
Cytochrome b5 reductase 4CYB5R46pter-q22.33Q7L1T6 details
Cytochrome P450 4A22CYP4A221p33Q5TCH4 details
Stearoyl-CoA desaturase 5SCD54q21.22Q86SK9 details
Cytochrome P450 4F22CYP4F22Q6NT55 details
Ferritin heavy chainFTH111q13P02794 details
Probable imidazolonepropionaseAMDHD112q23.1Q96NU7 details
Molybdenum cofactor sulfuraseMOCOS18q12Q96EN8 details
PirinPIRXp22.2O00625 details
Receptors
Protein NameGene NameLocusUniprot IDDetails
Retinal dehydrogenase 2ALDH1A215q21.3O94788 details
Aldo-keto reductase family 1 member C3AKR1C310p15-p14P42330 details
Aldo-keto reductase family 1 member C2AKR1C210p15-p14P52895 details
Alcohol dehydrogenase class 4 mu/sigma chainADH74q23-q24P40394 details
Nitric oxide synthase, brainNOS112q24.2-q24.31P29475 details
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialCYP27B112q13.1-q13.3O15528 details
25-hydroxycholesterol 7-alpha-hydroxylaseCYP7B18q21.3O75881 details
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialCYP24A120q13Q07973 details
Superoxide dismutase [Cu-Zn]SOD121q22.11P00441 details
Transcriptional Factors
Protein NameGene NameLocusUniprot IDDetails
Dihydrofolate reductaseDHFR5q11.2-q13.2P00374 details
Nitric oxide synthase, brainNOS112q24.2-q24.31P29475 details
CatalaseCAT11p13P04040 details
Superoxide dismutase [Mn], mitochondrialSOD26q25.3P04179 details
PirinPIRXp22.2O00625 details
Concentrations Data
Not Available
HMDB IDHMDB0059597
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FoodDB IDFDB030899
KNApSAcK IDNot Available
Chemspider ID1010
KEGG Compound IDC00080
BioCyc IDPROTON
BiGG IDNot Available
Wikipedia LinkHydrogen ion
METLIN IDNot Available
PubChem Compound1038
PDB IDNot Available
ChEBI ID15378
References
General ReferencesNot Available

Only showing the first 10 proteins. There are 287 proteins in total.

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Enzymes

Enzyme Details
1. Fatty acid synthase
General function:
Involved in transferase activity
Specific function:
Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
Gene Name:
FASN
Uniprot ID:
P49327
Molecular weight:
273424.06
Enzyme Details
2. Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial
General function:
Involved in oxidoreductase activity
Specific function:
Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.
Gene Name:
ALDH6A1
Uniprot ID:
Q02252
Molecular weight:
57839.31
Enzyme Details
3. Dihydrolipoyl dehydrogenase, mitochondrial
General function:
Involved in oxidoreductase activity
Specific function:
Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes. Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction.
Gene Name:
DLD
Uniprot ID:
P09622
Molecular weight:
54176.91
Enzyme Details
4. Aldo-keto reductase family 1 member C4
General function:
Involved in oxidoreductase activity
Specific function:
Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
Gene Name:
AKR1C4
Uniprot ID:
P17516
Molecular weight:
37094.57
Enzyme Details
5. Carbonyl reductase [NADPH] 1
General function:
Involved in oxidoreductase activity
Specific function:
NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
Gene Name:
CBR1
Uniprot ID:
P16152
Molecular weight:
30374.73
Enzyme Details
6. Carbonyl reductase [NADPH] 3
General function:
Involved in oxidoreductase activity
Specific function:
Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro).
Gene Name:
CBR3
Uniprot ID:
O75828
Molecular weight:
30849.97
Enzyme Details
7. Tyrosinase
General function:
Involved in oxidoreductase activity
Specific function:
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.
Gene Name:
TYR
Uniprot ID:
P14679
Molecular weight:
60392.69
Enzyme Details
8. Aldose reductase
General function:
Involved in oxidoreductase activity
Specific function:
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
Gene Name:
AKR1B1
Uniprot ID:
P15121
Molecular weight:
35853.125
Enzyme Details
9. Short-chain specific acyl-CoA dehydrogenase, mitochondrial
General function:
Involved in acyl-CoA dehydrogenase activity
Specific function:
Not Available
Gene Name:
ACADS
Uniprot ID:
P16219
Molecular weight:
44296.705
Enzyme Details
10. NADH-cytochrome b5 reductase 3
General function:
Involved in oxidoreductase activity
Specific function:
Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction.
Gene Name:
CYB5R3
Uniprot ID:
P00387
Molecular weight:
34234.55

Transporters

Enzyme Details
1. Fatty acid synthase
General function:
Involved in transferase activity
Specific function:
Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein.
Gene Name:
FASN
Uniprot ID:
P49327
Molecular weight:
273424.06
Enzyme Details
2. Aldo-keto reductase family 1 member C4
General function:
Involved in oxidoreductase activity
Specific function:
Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
Gene Name:
AKR1C4
Uniprot ID:
P17516
Molecular weight:
37094.57
Enzyme Details
3. Nitric oxide synthase, inducible
General function:
Involved in oxidoreductase activity
Specific function:
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
Gene Name:
NOS2
Uniprot ID:
P35228
Molecular weight:
131116.3
Enzyme Details
4. Cytosolic 10-formyltetrahydrofolate dehydrogenase
General function:
Involved in formyltetrahydrofolate dehydrogenase activity
Specific function:
Not Available
Gene Name:
ALDH1L1
Uniprot ID:
O75891
Molecular weight:
99752.535
Enzyme Details
5. Cytochrome b-c1 complex subunit Rieske, mitochondrial
General function:
Involved in oxidoreductase activity
Specific function:
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. The transit peptide of the Rieske protein seems to form part of the bc1 complex and is considered to be the subunit 11/IX of that complex (By similarity).
Gene Name:
UQCRFS1
Uniprot ID:
P47985
Molecular weight:
29667.695
Enzyme Details
6. Glycerol-3-phosphate dehydrogenase 1-like protein
General function:
Involved in oxidoreductase activity
Specific function:
Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L.
Gene Name:
GPD1L
Uniprot ID:
Q8N335
Molecular weight:
38418.44
Enzyme Details
7. Mitochondrial 10-formyltetrahydrofolate dehydrogenase
General function:
Involved in formyltetrahydrofolate dehydrogenase activity
Specific function:
Not Available
Gene Name:
ALDH1L2
Uniprot ID:
Q3SY69
Molecular weight:
101744.98

Only showing the first 10 proteins. There are 287 proteins in total.

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