Identification |
HMDB Protein ID
| CDBP00411 |
Secondary Accession Numbers
| Not Available |
Name
| S-adenosylmethionine decarboxylase proenzyme |
Description
| Not Available |
Synonyms
|
- AdoMetDC
- S-adenosylmethionine decarboxylase alpha chain
- S-adenosylmethionine decarboxylase beta chain
- SAMDC
- SubName: Adenosylmethionine decarboxylase 1, isoform CRA_b
- SubName: Putative uncharacterized protein DKFZp313L1234
|
Gene Name
| AMD1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in adenosylmethionine decarboxylase activity |
Specific Function
| Not Available |
GO Classification
|
Biological Process |
small molecule metabolic process |
S-adenosylmethioninamine biosynthetic process |
spermidine biosynthetic process |
spermine biosynthetic process |
Cellular Component |
cytosol |
Function |
catalytic activity |
lyase activity |
carbon-carbon lyase activity |
carboxy-lyase activity |
adenosylmethionine decarboxylase activity |
Molecular Function |
adenosylmethionine decarboxylase activity |
Process |
cellular amino acid derivative metabolic process |
cellular biogenic amine metabolic process |
polyamine metabolic process |
polyamine biosynthetic process |
spermine biosynthetic process |
cellular amino acid and derivative metabolic process |
metabolic process |
cellular metabolic process |
spermidine biosynthetic process |
|
Cellular Location
|
Not Available
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Spermidine and Spermine Biosynthesis | | Not Available | Methionine Metabolism | | | S-adenosylmethioninamine biosynthesis | Not Available | Not Available | Cysteine and methionine metabolism | Not Available | | Cystathionine Beta-Synthase Deficiency | | Not Available |
|
Gene Properties |
Chromosome Location
| 6 |
Locus
| 6q21 |
SNPs
| AMD1 |
Gene Sequence
|
>1005 bp
ATGGAAGCTGCACATTTTTTCGAAGGGACCGAGAAGCTGCTGGAGGTTTGGTTCTCCCGG
CAGCAGCCCGACGCAAACCAAGGATCTGGGGATCTTCGCACTATCCCAAGATCTGAGTGG
GACATACTTTTGAAGGATGTGCAATGTTCAATCATAAGTGTGACAAAAACTGACAAGCAG
GAAGCTTATGTACTCAGTGAGAGTAGCATGTTTGTCTCCAAGAGACGTTTCATTTTGAAG
ACATGTGGTACCACCCTCTTGCTGAAAGCACTGGTTCCCCTGTTGAAGCTTGCTAGGGAT
TACAGTGGGTTTGACTCAATTCAAAGCTTCTTTTATTCTCGTAAGAATTTCATGAAGCCT
TCTCACCAAGGGTACCCACACCGGAATTTCCAGGAAGAAATAGAGTTTCTTAATGCAATT
TTCCCAAATGGAGCAGCATATTGTATGGGACGTATGAATTCTGACTGTTGGTACTTATAT
ACTCTGGATTTCCCAGAGAGTCGGGTAATCAGTCAGCCAGATCAAACCTTGGAAATTCTG
ATGAGTGAGCTTGACCCAGCAGTTATGGACCAGTTCTACATGAAAGATGGTGTTACTGCA
AAGGATGTCACTCGTGAGAGTGGAATTCGTGACCTGATACCAGGTTCTGTCATTGATGCC
ACAATGTTCAATCCTTGTGGGTATTCGATGAATGGAATGAAATCGGATGGAACTTATTGG
ACTATTCACATCACTCCAGAACCAGAATTTTCTTATGTTAGCTTTGAAACAAACTTAAGT
CAGACCTCCTATGATGACCTGATCAGGAAAGTTGTAGAAGTCTTCAAGCCAGGAAAATTT
GTGACCACCTTGTTTGTTAATCAGAGTTCTAAATGTCGCACAGTGCTTGCTTCGCCCCAG
AAGATTGAAGGTTTTAAGCGTCTTGATTGCCAGAGTGCTATGTTCAATGATTACAATTTT
GTTTTTACCAGTTTTGCTAAGAAGCAGCAACAACAGCAGAGTTGA
|
Protein Properties |
Number of Residues
| 334 |
Molecular Weight
| 21301.015 |
Theoretical pI
| 5.073 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>S-adenosylmethionine decarboxylase proenzyme
MEAAHFFEGTEKLLEVWFSRQQPDANQGSGDLRTIPRSEWDILLKDVQCSIISVTKTDKQ
EAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKP
SHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFPESRVISQPDQTLEIL
MSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATMFNPCGYSMNGMKSDGTYW
TIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLASPQ
KIEGFKRLDCQSAMFNDYNFVFTSFAKKQQQQQS
|
External Links |
GenBank ID Protein
| 55664717 |
UniProtKB/Swiss-Prot ID
| P17707 |
UniProtKB/Swiss-Prot Entry Name
| DCAM_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| AL357515 |
GeneCard ID
| AMD1 |
GenAtlas ID
| AMD1 |
HGNC ID
| HGNC:457 |
References |
General References
| Not Available |