Cannabis Compound Database: Showing Protein Extracellular superoxide dismutase [Cu-Zn] (CDBP02274)

Identification Biological properties Gene properties Protein properties External links References XML Show 7 compounds

Identification

HMDB Protein ID

CDBP02274

Secondary Accession Numbers

Not Available

Name

Extracellular superoxide dismutase [Cu-Zn]

Description

Not Available

Synonyms

EC-SOD

Gene Name

SOD3

Protein Type

Enzyme

Biological Properties

General Function

Involved in metal ion binding

Specific Function

Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.

GO Classification

Biological Process
removal of superoxide radicals
response to hypoxia
response to copper ion
Cellular Component
nucleus
trans-Golgi network
extracellular space
extracellular matrix
cytosol
mitochondrion
Function
ion binding
cation binding
metal ion binding
binding
Molecular Function
superoxide dismutase activity
zinc ion binding
copper ion binding
heparin binding
Process
superoxide metabolic process
metabolic process
cellular metabolic process
oxidation reduction
oxygen and reactive oxygen species metabolic process

Cellular Location

Secreted
extracellular space

Pathways

Name	SMPDB/Pathwhiz	KEGG
Degradation of Superoxides		Not Available

Gene Properties

Chromosome Location

Locus

4p15.2

SNPs

SOD3

Gene Sequence

>723 bp
ATGCTGGCGCTACTGTGTTCCTGCCTGCTCCTGGCAGCCGGTGCCTCGGACGCCTGGACG
GGCGAGGACTCGGCGGAGCCCAACTCTGACTCGGCGGAGTGGATCCGAGACATGTACGCC
AAGGTCACGGAGATCTGGCAGGAGGTCATGCAGCGGCGGGACGACGACGGCACGCTCCAC
GCCGCCTGCCAGGTGCAGCCGTCGGCCACGCTGGACGCCGCGCAGCCCCGGGTGACCGGC
GTCGTCCTCTTCCGGCAGCTTGCGCCCCGCGCCAAGCTCGACGCCTTCTTCGCCCTGGAG
GGCTTCCCGACCGAGCCGAACAGCTCCAGCCGCGCCATCCACGTGCACCAGTTCGGGGAC
CTGAGCCAGGGCTGCGAGTCCACCGGGCCCCACTACAACCCGCTGGCCGTGCCGCACCCG
CAGCACCCGGGCGACTTCGGCAACTTCGCGGTCCGCGACGGCAGCCTCTGGAGGTACCGC
GCCGGCCTGGCCGCCTCGCTCGCGGGCCCGCACTCCATCGTGGGCCGGGCCGTGGTCGTC
CACGCTGGCGAGGACGACCTGGGCCGCGGCGGCAACCAGGCCAGCGTGGAGAACGGGAAC
GCGGGCCGGCGGCTGGCCTGCTGCGTGGTGGGCGTGTGCGGGCCCGGGCTCTGGGAGCGC
CAGGCGCGGGAGCACTCAGAGCGCAAGAAGCGGCGGCGCGAGAGCGAGTGCAAGGCCGCC
TGA

Protein Properties

Number of Residues

240

Molecular Weight

25850.675

Theoretical pI

6.604

Pfam Domain Function

Sod_Cu (PF00080 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Extracellular superoxide dismutase [Cu-Zn]
MLALLCSCLLLAAGASDAWTGEDSAEPNSDSAEWIRDMYAKVTEIWQEVMQRRDDDGALH
AACQVQPSATLDAAQPRVTGVVLFRQLAPRAKLDAFFALEGFPTEPNSSSRAIHVHQFGD
LSQGCESTGPHYNPLAVPHPQHPGDFGNFAVRDGSLWRYRAGLAASLAGPHSIVGRAVVV
HAGEDDLGRGGNQASVENGNAGRRLACCVVGVCGPGLWERQAREHSERKKRRRESECKAA

External Links

GenBank ID Protein

338284

UniProtKB/Swiss-Prot ID

P08294

UniProtKB/Swiss-Prot Entry Name

SODE_HUMAN

PDB IDs