| Identification |
|---|
| HMDB Protein ID
| CDBP00761 |
| Secondary Accession Numbers
| Not Available |
| Name
| Glutathione S-transferase A1 |
| Description
| Not Available |
| Synonyms
|
- GST HA subunit 1
- GST class-alpha member 1
- GST-epsilon
- GSTA1-1
- GTH1
|
| Gene Name
| GSTA1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in glutathione transferase activity |
| Specific Function
| Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
|
| GO Classification
|
| Biological Process |
| glutathione metabolic process |
| xenobiotic metabolic process |
| Cellular Component |
| cytosol |
| Function |
| catalytic activity |
| transferase activity |
| transferase activity, transferring alkyl or aryl (other than methyl) groups |
| glutathione transferase activity |
| Molecular Function |
| glutathione transferase activity |
| Process |
| metabolic process |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Metabolism of xenobiotics by cytochrome P450 | Not Available |  | | Drug metabolism - cytochrome P450 | Not Available |  | | Chemical carcinogenesis | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| 6 |
| Locus
| 6p12.1 |
| SNPs
| GSTA1 |
| Gene Sequence
|
>669 bp
ATGGCAGAGAAGCCCAAGCTCCACTACTTCAATGCACGGGGCAGAATGGAGTCCACCCGG
TGGCTCCTGGCTGCAGCTGGAGTAGAGTTTGAAGAGAAATTTATAAAATCTGCAGAAGAT
TTGGACAAGTTAAGAAATGATGGATATTTGATGTTCCAGCAAGTGCCAATGGTTGAGATT
GATGGGATGAAGCTGGTGCAGACCAGAGCCATTCTCAACTACATTGCCAGCAAATACAAC
CTCTATGGGAAAGACATAAAGGAGAGAGCCCTGATTGATATGTATATAGAAGGTATAGCA
GATTTGGGTGAAATGATCCTCCTTCTGCCCGTATGTCCACCTGAGGAAAAAGATGCCAAG
CTTGCCTTGATCAAGGAGAAAATAAAAAATCGCTACTTCCCTGCCTTTGAAAAAGTCTTA
AAGAGCCATGGACAAGACTACCTTGTTGGCAACAAGCTGAGCCGGGCTGACATTCATCTG
GTGGAACTTCTCTACTACGTCGAGGAGCTTGACTCCAGTCTTATCTCCAGCTTCCCTCTG
CTGAAGGCCCTGAAAACCAGAATCAGCAACCTGCCCACAGTGAAGAAGTTTCTACAGCCT
GGCAGCCCAAGGAAGCCTCCCATGGATGAGAAATCTTTAGAAGAAGCAAGGAAGATTTTC
AGGTTTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 222 |
| Molecular Weight
| 25630.785 |
| Theoretical pI
| 8.883 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Glutathione S-transferase A1
MAEKPKLHYFNARGRMESTRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEI
DGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDAK
LALIKEKIKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPL
LKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEEARKIFRF
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| P08263 |
| UniProtKB/Swiss-Prot Entry Name
| GSTA1_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| M15872 |
| GeneCard ID
| GSTA1 |
| GenAtlas ID
| GSTA1 |
| HGNC ID
| HGNC:4626 |
| References |
|---|
| General References
| Not Available |