Identification
HMDB Protein ID CDBP00949
Secondary Accession Numbers Not Available
Name Peroxisomal trans-2-enoyl-CoA reductase
Description Not Available
Synonyms
  1. 2,4-dienoyl-CoA reductase-related protein
  2. DCR-RP
  3. HPDHase
  4. TERP
  5. pVI-ARL
Gene Name PECR
Protein Type Enzyme
Biological Properties
General Function Involved in regulation of apoptosis
Specific Function Participates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity.
GO Classification
Biological Process
fatty acid biosynthetic process
phytol metabolic process
Cellular Component
mitochondrion
peroxisomal membrane
Function
binding
catalytic activity
oxidoreductase activity
Molecular Function
trans-2-enoyl-CoA reductase (NADPH) activity
nucleotide binding
Process
metabolic process
biological regulation
regulation of biological process
regulation of cell death
regulation of programmed cell death
regulation of apoptosis
regulation of cellular process
oxidation reduction
Cellular Location
  1. Peroxisome
Pathways
Gene Properties
Chromosome Location 2
Locus 2q35
SNPs PECR
Gene Sequence
>912 bp
ATGGCCTCCTGGGCTAAGGGCAGGAGCTACCTGGCGCCTGGTTTGCTGCAGGGCCAAGTG
GCCATCGTCACCGGCGGGGCCACGGGCATCGGAAAAGCCATCGTGAAGGAGCTCCTGGAG
CTGGGGAGTAATGTGGTCATTGCATCCCGTAAGTTGGAGAGATTGAAGTCTGCGGCAGAT
GAACTGCAGGCCAACCTACCTCCCACAAAGCAGGCACGAGTCATTCCCATACAATGCAAC
ATCCGGAATGAGGAGGAGGTGAATAATTTGGTCAAATCTACCTTAGATACTTTTGGTAAG
ATCAATTTCTTGGTGAACAATGGAGGAGGCCAGTTTCTTTCCCCTGCTGAACACATCAGT
TCTAAGGGATGGCACGCTGTGCTTGAGACCAACCTGACGGGTACCTTCTACATGTGCAAA
GCAGTTTACAGCTCCTGGATGAAAGAGCATGGAGGATCTATCGTCAATATCATTGTCCCT
ACTAAAGCTGGATTTCCATTAGCTGTGCATTCTGGAGCTGCAAGAGCAGGTGTTTACAAC
CTCACCAAATCTTTAGCTTTGGAATGGGCCTGCAGTGGAATACGGATCAATTGTGTTGCC
CCTGGAGTTATTTATTCCCAGACTGCTGTGGAGAACTATGGTTCCTGGGGACAAAGCTTC
TTTGAAGGGTCTTTTCAGAAAATCCCCGCTAAACGAATTGGTGTTCCTGAGGAGGTCTCC
TCTGTGGTCTGCTTCCTACTGTCTCCTGCAGCTTCCTTCATCACTGGACAGTCAGTGGAT
GTGGATGGGGGCCGGAGTCTCTATACTCACTCGTATGAGGTACCAGATCATGACAACTGG
CCCAAGGGAGCAGGGGACCTTTCTGTTGTCAAAAAGATGAAGGAGACCTTTAAGGAGAAA
GCTAAGCTCTGA
Protein Properties
Number of Residues 303
Molecular Weight 32544.11
Theoretical pI 8.807
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Peroxisomal trans-2-enoyl-CoA reductase
MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD
ELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHIS
SKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYN
LTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVS
SVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKGAGDLSVVKKMKETFKEK
AKL
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q9BY49
UniProtKB/Swiss-Prot Entry Name PECR_HUMAN
PDB IDs
GenBank Gene ID AF232009
GeneCard ID PECR
GenAtlas ID PECR
HGNC ID HGNC:18281
References
General References Not Available