Identification |
HMDB Protein ID
| CDBP00949 |
Secondary Accession Numbers
| Not Available |
Name
| Peroxisomal trans-2-enoyl-CoA reductase |
Description
| Not Available |
Synonyms
|
- 2,4-dienoyl-CoA reductase-related protein
- DCR-RP
- HPDHase
- TERP
- pVI-ARL
|
Gene Name
| PECR |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in regulation of apoptosis |
Specific Function
| Participates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity.
|
GO Classification
|
Biological Process |
fatty acid biosynthetic process |
phytol metabolic process |
Cellular Component |
mitochondrion |
peroxisomal membrane |
Function |
binding |
catalytic activity |
oxidoreductase activity |
Molecular Function |
trans-2-enoyl-CoA reductase (NADPH) activity |
nucleotide binding |
Process |
metabolic process |
biological regulation |
regulation of biological process |
regulation of cell death |
regulation of programmed cell death |
regulation of apoptosis |
regulation of cellular process |
oxidation reduction |
|
Cellular Location
|
- Peroxisome
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Biosynthesis of unsaturated fatty acids | Not Available | | Peroxisome | Not Available | |
|
Gene Properties |
Chromosome Location
| 2 |
Locus
| 2q35 |
SNPs
| PECR |
Gene Sequence
|
>912 bp
ATGGCCTCCTGGGCTAAGGGCAGGAGCTACCTGGCGCCTGGTTTGCTGCAGGGCCAAGTG
GCCATCGTCACCGGCGGGGCCACGGGCATCGGAAAAGCCATCGTGAAGGAGCTCCTGGAG
CTGGGGAGTAATGTGGTCATTGCATCCCGTAAGTTGGAGAGATTGAAGTCTGCGGCAGAT
GAACTGCAGGCCAACCTACCTCCCACAAAGCAGGCACGAGTCATTCCCATACAATGCAAC
ATCCGGAATGAGGAGGAGGTGAATAATTTGGTCAAATCTACCTTAGATACTTTTGGTAAG
ATCAATTTCTTGGTGAACAATGGAGGAGGCCAGTTTCTTTCCCCTGCTGAACACATCAGT
TCTAAGGGATGGCACGCTGTGCTTGAGACCAACCTGACGGGTACCTTCTACATGTGCAAA
GCAGTTTACAGCTCCTGGATGAAAGAGCATGGAGGATCTATCGTCAATATCATTGTCCCT
ACTAAAGCTGGATTTCCATTAGCTGTGCATTCTGGAGCTGCAAGAGCAGGTGTTTACAAC
CTCACCAAATCTTTAGCTTTGGAATGGGCCTGCAGTGGAATACGGATCAATTGTGTTGCC
CCTGGAGTTATTTATTCCCAGACTGCTGTGGAGAACTATGGTTCCTGGGGACAAAGCTTC
TTTGAAGGGTCTTTTCAGAAAATCCCCGCTAAACGAATTGGTGTTCCTGAGGAGGTCTCC
TCTGTGGTCTGCTTCCTACTGTCTCCTGCAGCTTCCTTCATCACTGGACAGTCAGTGGAT
GTGGATGGGGGCCGGAGTCTCTATACTCACTCGTATGAGGTACCAGATCATGACAACTGG
CCCAAGGGAGCAGGGGACCTTTCTGTTGTCAAAAAGATGAAGGAGACCTTTAAGGAGAAA
GCTAAGCTCTGA
|
Protein Properties |
Number of Residues
| 303 |
Molecular Weight
| 32544.11 |
Theoretical pI
| 8.807 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Peroxisomal trans-2-enoyl-CoA reductase
MASWAKGRSYLAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAAD
ELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHIS
SKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKAGFPLAVHSGAARAGVYN
LTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVS
SVVCFLLSPAASFITGQSVDVDGGRSLYTHSYEVPDHDNWPKGAGDLSVVKKMKETFKEK
AKL
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| Q9BY49 |
UniProtKB/Swiss-Prot Entry Name
| PECR_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| AF232009 |
GeneCard ID
| PECR |
GenAtlas ID
| PECR |
HGNC ID
| HGNC:18281 |
References |
General References
| Not Available |