Record Information
Version1.0
Created at2020-04-17 18:49:32 UTC
Updated at2020-11-18 16:38:59 UTC
CannabisDB IDCDB004910
Secondary Accession NumbersNot Available
Cannabis Compound Identification
Common NameOxygen
DescriptionOxygen, also known as dioxygene or O2, belongs to the class of inorganic compounds known as other non-metal oxides. These are inorganic compounds containing an oxygen atom of an oxidation state of -2, in which the heaviest atom bonded to the oxygen belongs to the class of 'other non-metals'. Oxygen is possibly neutral. Oxygen exists in all living species, ranging from bacteria to humans. In humans, oxygen is involved in ibuprofen action pathway. Outside of the human body, Oxygen has been detected, but not quantified in, several different foods, such as epazotes, oval-leaf huckleberries, barley, alaska blueberries, and boysenberries. This could make oxygen a potential biomarker for the consumption of these foods. Oxygen is expected to be in Cannabis as all living plants are known to produce and metabolize it.
Structure
Thumb
Synonyms
ValueSource
[OO]ChEBI
DioxygeneChEBI
DisauerstoffChEBI
e 948ChEBI
e-948ChEBI
e948ChEBI
Molecular oxygenChEBI
O2ChEBI
OXYGEN moleculeChEBI
DioxygenHMDB
Oxygen-16HMDB
Oxygen 16HMDB
Chemical FormulaO2
Average Molecular Weight32.0
Monoisotopic Molecular Weight31.9898
IUPAC Namedioxygen
Traditional Namesinglet oxygen
CAS Registry Number7782-44-7
SMILES
O=O
InChI Identifier
InChI=1S/O2/c1-2
InChI KeyMYMOFIZGZYHOMD-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of inorganic compounds known as other non-metal oxides. These are inorganic compounds containing an oxygen atom of an oxidation state of -2, in which the heaviest atom bonded to the oxygen belongs to the class of 'other non-metals'.
KingdomInorganic compounds
Super ClassHomogeneous non-metal compounds
ClassOther non-metal organides
Sub ClassOther non-metal oxides
Direct ParentOther non-metal oxides
Alternative Parents
Substituents
  • Other non-metal oxide
  • Inorganic oxide
Molecular FrameworkNot Available
External Descriptors
Ontology
Disposition

Route of exposure:

Source:

Biological location:

Role

Industrial application:

Physical Properties
StateLiquid
Experimental Properties
PropertyValueReference
Melting Point-218.4 °CNot Available
Boiling PointNot AvailableNot Available
Water Solubility37.5 mg/mL at 21 °CNot Available
logP0.65HANSCH,C ET AL. (1995)
Predicted Properties
PropertyValueSource
logP-0.28ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area34.14 ŲChemAxon
Rotatable Bond Count0ChemAxon
Refractivity2.89 m³·mol⁻¹ChemAxon
Polarizability1.53 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Spectra
EI-MS/GC-MS
TypeDescriptionSplash KeyView
Predicted GC-MSOxygen, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positivesplash10-001i-9000000000-2e78a9ed80eede2ed33aSpectrum
MS/MS
TypeDescriptionSplash KeyView
Predicted MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-001i-9000000000-a9a93dd42f2cfa0b34c4Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-001i-9000000000-a9a93dd42f2cfa0b34c4Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-001i-9000000000-a9a93dd42f2cfa0b34c4Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-001i-9000000000-5e864878b295db174473Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-001i-9000000000-5e864878b295db174473Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-001i-9000000000-5e864878b295db174473Spectrum
NMRNot Available
Pathways
Pathways
Protein Targets
Enzymes
Protein NameGene NameLocusUniprot IDDetails
TyrosinaseTYR11q14-q21P14679 details
Peroxisomal sarcosine oxidasePIPOX17q11.2Q9P0Z9 details
Peroxisomal N(1)-acetyl-spermine/spermidine oxidasePAOX10q26.3Q6QHF9 details
Aldehyde oxidaseAOX12q33Q06278 details
Lathosterol oxidaseSC5DL11q23.3O75845 details
Dimethylaniline monooxygenase [N-oxide-forming] 5FMO51q21.1P49326 details
Peroxisomal acyl-coenzyme A oxidase 1ACOX117q25.1Q15067 details
D-aspartate oxidaseDDO6q21Q99489 details
Heme oxygenase 2HMOX216p13.3P30519 details
Squalene monooxygenaseSQLE8q24.1Q14534 details
Dimethylaniline monooxygenase [N-oxide-forming] 2FMO21q24.3Q99518 details
Amine oxidase [flavin-containing] BMAOBXp11.23P27338 details
Dimethylaniline monooxygenase [N-oxide-forming] 4FMO41q24.3P31512 details
Amine oxidase [flavin-containing] AMAOAXp11.3P21397 details
Dimethylaniline monooxygenase [N-oxide-forming] 3FMO31q24.3P31513 details
Xanthine dehydrogenase/oxidaseXDH2p23.1P47989 details
Dihydroorotate dehydrogenase (quinone), mitochondrialDHODH16q22Q02127 details
Dimethylaniline monooxygenase [N-oxide-forming] 1FMO11q24.3Q01740 details
Peroxisomal acyl-coenzyme A oxidase 3ACOX34p15.3O15254 details
Heme oxygenase 1HMOX122q13.1P09601 details
D-amino-acid oxidaseDAO12q24P14920 details
Coproporphyrinogen-III oxidase, mitochondrialCPOX3q12P36551 details
Peptidyl-glycine alpha-amidating monooxygenasePAM5q14-q21P19021 details
Dopamine beta-hydroxylaseDBH9q34P09172 details
Methylsterol monooxygenase 1MSMO14q32-q34Q15800 details
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylatingNSDHLXq28Q15738 details
Lanosterol 14-alpha demethylaseCYP51A17q21.2Q16850 details
Phytanoyl-CoA dioxygenase, peroxisomalPHYH10p13O14832 details
Tyrosine 3-monooxygenaseTH11p15.5P07101 details
Phenylalanine-4-hydroxylasePAH12q22-q24.2P00439 details
Peroxiredoxin-6PRDX61q25.1P30041 details
Prolyl 4-hydroxylase subunit alpha-2P4HA25q31O15460 details
Prolyl 4-hydroxylase subunit alpha-1P4HA110q21.3-q23.1P13674 details
Acyl-CoA desaturaseSCD10q24.31O00767 details
Gamma-butyrobetaine dioxygenaseBBOX111p14.2O75936 details
Amiloride-sensitive amine oxidase [copper-containing]ABP17q36.1P19801 details
Membrane primary amine oxidaseAOC317q21Q16853 details
Retina-specific copper amine oxidaseAOC217q21O75106 details
Indoleamine 2,3-dioxygenase 1IDO18p12-p11P14902 details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1PLOD11p36.22Q02809 details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2PLOD23q24O00469 details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3PLOD37q22O60568 details
Tryptophan 5-hydroxylase 1TPH111p15.3-p14P17752 details
Tryptophan 5-hydroxylase 2TPH212q21.1Q8IWU9 details
Cholesterol 7-alpha-monooxygenaseCYP7A18q11-q12P22680 details
Pyridoxine-5'-phosphate oxidasePNPO17q21.32Q9NVS9 details
Protein-lysine 6-oxidaseLOX5q23.2P28300 details
Hydroxyacid oxidase 1HAO120p12Q9UJM8 details
Hydroxyacid oxidase 2HAO21p13.3-p13.1Q9NYQ3 details
Inositol oxygenaseMIOX22q13.3Q9UGB7 details
4-hydroxyphenylpyruvate dioxygenaseHPD12q24-qterP32754 details
Homogentisate 1,2-dioxygenaseHGD3q13.33Q93099 details
3-keto-steroid reductaseHSD17B71q23P56937 details
Nitric oxide synthase, inducibleNOS217q11.2-q12P35228 details
Nitric oxide synthase, brainNOS112q24.2-q24.31P29475 details
Nitric oxide synthase, endothelialNOS37q36P29474 details
Cysteine dioxygenase type 1CDO15q23.2Q16878 details
Arachidonate 5-lipoxygenaseALOX510q11.2P09917 details
Arachidonate 15-lipoxygenase BALOX15B17p13.1O15296 details
Arachidonate 12-lipoxygenase, 12S-typeALOX1217p13.1P18054 details
Prostaglandin G/H synthase 2PTGS21q25.2-q25.3P35354 details
Prostaglandin G/H synthase 1PTGS19q32-q33.3P23219 details
Arachidonate 15-lipoxygenaseALOX1517p13.3P16050 details
Leukotriene-B(4) omega-hydroxylase 1CYP4F219p13.12P78329 details
Leukotriene-B(4) omega-hydroxylase 2CYP4F319p13.2Q08477 details
Protoporphyrinogen oxidasePPOX1q22P50336 details
Aspartyl/asparaginyl beta-hydroxylaseASPH8q12.1Q12797 details
Sterol 26-hydroxylase, mitochondrialCYP27A12q33-qterQ02318 details
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialCYP27B112q13.1-q13.3O15528 details
Steroid 17-alpha-hydroxylase/17,20 lyaseCYP17A110q24.3P05093 details
Sulfite oxidase, mitochondrialSUOX12q13.2P51687 details
3-hydroxyanthranilate 3,4-dioxygenaseHAAO2p21P46952 details
Beta,beta-carotene 15,15'-monooxygenaseBCMO116q23.2Q9HAY6 details
CatalaseCAT11p13P04040 details
25-hydroxycholesterol 7-alpha-hydroxylaseCYP7B18q21.3O75881 details
Cytochrome c oxidase subunit 1MT-CO1P00395 details
Vitamin K-dependent gamma-carboxylaseGGCX2p12P38435 details
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialCYP24A120q13Q07973 details
Putative dimethylaniline monooxygenase [N-oxide-forming] 6FMO6PO60774 details
Superoxide dismutase [Mn], mitochondrialSOD26q25.3P04179 details
Superoxide dismutase [Cu-Zn]SOD121q22.11P00441 details
Cytochrome c oxidase subunit 7A1, mitochondrialCOX7A119q13.1P24310 details
Kynurenine 3-monooxygenaseKMO1q42-q44O15229 details
Spermine oxidaseSMOX20p13Q9NWM0 details
Vitamin D 25-hydroxylaseCYP2R111p15.2Q6VVX0 details
Cytochrome c oxidase subunit 7A2, mitochondrialCOX7A26q12P14406 details
Cholesterol 25-hydroxylaseCH25H10q23O95992 details
Dual oxidase 2DUOX215q15.3Q9NRD8 details
Cytochrome c oxidase subunit 6A2, mitochondrialCOX6A216pQ02221 details
Extracellular superoxide dismutase [Cu-Zn]SOD34p15.2P08294 details
Cytochrome c oxidase subunit 7B, mitochondrialCOX7BP24311 details
Cytochrome c oxidase subunit 7C, mitochondrialCOX7C5q14P15954 details
Cytochrome c oxidase subunit 5B, mitochondrialCOX5B2cen-q13P10606 details
Cytochrome c oxidase subunit 6B1COX6B119q13.1P14854 details
Cytochrome c oxidase subunit 7B2, mitochondrialCOX7B24p12Q8TF08 details
Cytochrome c oxidase subunit 4 isoform 1, mitochondrialCOX4I116q24.1P13073 details
Cytochrome c oxidase subunit 6B2COX6B219q13.42Q6YFQ2 details
Cytochrome c oxidase subunit 8A, mitochondrialCOX8A11q12-q13P10176 details
Cytochrome c oxidase subunit 6CCOX6C8q22.2P09669 details
Cytochrome c oxidase subunit 7A-related protein, mitochondrialCOX7A2L2p21O14548 details
Cytochrome c oxidase subunit 8C, mitochondrialCOX8C14q32.12Q7Z4L0 details
Trimethyllysine dioxygenase, mitochondrialTMLHEXq28Q9NVH6 details
Cholesterol 24-hydroxylaseCYP46A114q32.1Q9Y6A2 details
Tryptophan 2,3-dioxygenaseTDO24q31-q32P48775 details
24-hydroxycholesterol 7-alpha-hydroxylaseCYP39A16p21.1-p11.2Q9NYL5 details
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylaseCYP8B13p22.1Q9UNU6 details
Cytochrome c oxidase subunit 2MT-CO2P00403 details
Cytochrome c oxidase subunit 6A1, mitochondrialCOX6A112q24.2|12q24.2P12074 details
Cytochrome c oxidase subunit 4 isoform 2, mitochondrialCOX4I220q11.21Q96KJ9 details
Dual oxidase 1DUOX115q15.3Q9NRD9 details
Stearoyl-CoA desaturase 5SCD54q21.22Q86SK9 details
Putative uncharacterized protein DKFZp686B0215DKFZp686B0215Q5HYI4 details
Indoleamine 2,3-dioxygenase 2IDO28p11.21Q6ZQW0 details
Cytochrome P450, family 1, subfamily A, polypeptide 1CYP1A115q24.1A0N0X8 details
Ubiquinone biosynthesis monooxygenase COQ6COQ6Q9Y2Z9 details
Lysyl oxidase homolog 2LOXL28p21.3Q9Y4K0 details
FAD-linked sulfhydryl oxidase ALRGFER16p13.3-p13.12P55789 details
Protein-methionine sulfoxide oxidase MICAL1MICAL16q21Q8TDZ2 details
Protein-methionine sulfoxide oxidase MICAL2MICAL211p15.3O94851 details
Protein-methionine sulfoxide oxidase MICAL3MICAL322q11.21Q7RTP6 details
L-amino-acid oxidaseIL4I119q13.3-q13.4Q96RQ9 details
Prenylcysteine oxidase 1PCYOX12p13.3Q9UHG3 details
Sulfhydryl oxidase 1QSOX11q24O00391 details
Sulfhydryl oxidase 2QSOX29q34.3Q6ZRP7 details
2-aminoethanethiol dioxygenaseADO10q21.3Q96SZ5 details
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2ALKBH212q24.11Q6NS38 details
Beta,beta-carotene 9',10'-oxygenaseBCO211q23.1Q9BYV7 details
Prolyl 3-hydroxylase 1LEPRE11p34.1Q32P28 details
Prolyl 3-hydroxylase 2LEPREL13q28Q8IVL5 details
Prolyl 3-hydroxylase 3LEPREL212q13Q8IVL6 details
Prolyl 4-hydroxylase subunit alpha-3P4HA311q13.4Q7Z4N8 details
Lysine-specific demethylase 2AKDM2A11q13.2Q9Y2K7 details
Lysine-specific demethylase 2BKDM2B12q24.31Q8NHM5 details
Deoxyhypusine hydroxylaseDOHH19p13.3Q9BU89 details
Egl nine homolog 1EGLN11q42.1Q9GZT9 details
Egl nine homolog 2EGLN219q13.2Q96KS0 details
Egl nine homolog 3EGLN314q13.1Q9H6Z9 details
Transmembrane prolyl 4-hydroxylaseP4HTM3p21.3Q9NXG6 details
Cytochrome P450, family 21, subfamily A, polypeptide 2CYP21A26p21.3Q08AG9 details
CP proteinCP3q23-q25A5PL27 details
NOS1 mutantNOS112q24.2-q24.31B3VK56 details
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenaseADI12p25.3Q9BV57 details
Alkylglycerol monooxygenaseAGMO7p21.2Q6ZNB7 details
Steroid 21-hydroxylaseCYP21A26p21.3P08686 details
Lysine-specific demethylase 8KDM816p12.1Q8N371 details
Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINAMINA3q11.2Q8IUF8 details
Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66NO6614q24.3Q9H6W3 details
Histone lysine demethylase PHF8PHF8Xp11.22Q9UPP1 details
Methylcytosine dioxygenase TET1TET110q21Q8NFU7 details
Methylcytosine dioxygenase TET2TET24q24Q6N021 details
Methylcytosine dioxygenase TET3TET32p13.1O43151 details
Transporters
Protein NameGene NameLocusUniprot IDDetails
Nitric oxide synthase, inducibleNOS217q11.2-q12P35228 details
Metal Bindings
Protein NameGene NameLocusUniprot IDDetails
Aldehyde oxidaseAOX12q33Q06278 details
Lathosterol oxidaseSC5DL11q23.3O75845 details
Heme oxygenase 2HMOX216p13.3P30519 details
Xanthine dehydrogenase/oxidaseXDH2p23.1P47989 details
Heme oxygenase 1HMOX122q13.1P09601 details
Peptidyl-glycine alpha-amidating monooxygenasePAM5q14-q21P19021 details
Dopamine beta-hydroxylaseDBH9q34P09172 details
Methylsterol monooxygenase 1MSMO14q32-q34Q15800 details
Lanosterol 14-alpha demethylaseCYP51A17q21.2Q16850 details
Phytanoyl-CoA dioxygenase, peroxisomalPHYH10p13O14832 details
Tyrosine 3-monooxygenaseTH11p15.5P07101 details
Phenylalanine-4-hydroxylasePAH12q22-q24.2P00439 details
Prolyl 4-hydroxylase subunit alpha-2P4HA25q31O15460 details
Prolyl 4-hydroxylase subunit alpha-1P4HA110q21.3-q23.1P13674 details
Acyl-CoA desaturaseSCD10q24.31O00767 details
Gamma-butyrobetaine dioxygenaseBBOX111p14.2O75936 details
Amiloride-sensitive amine oxidase [copper-containing]ABP17q36.1P19801 details
Membrane primary amine oxidaseAOC317q21Q16853 details
Retina-specific copper amine oxidaseAOC217q21O75106 details
Cytochrome P450 4A11CYP4A111p33Q02928 details
Indoleamine 2,3-dioxygenase 1IDO18p12-p11P14902 details
Cytochrome P450 11B1, mitochondrialCYP11B18q21P15538 details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1PLOD11p36.22Q02809 details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2PLOD23q24O00469 details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3PLOD37q22O60568 details
Tryptophan 5-hydroxylase 1TPH111p15.3-p14P17752 details
Ferritin, mitochondrialFTMT5q21.3Q8N4E7 details
Tryptophan 5-hydroxylase 2TPH212q21.1Q8IWU9 details
CeruloplasminCP3q23-q25P00450 details
Cholesterol 7-alpha-monooxygenaseCYP7A18q11-q12P22680 details
Protein-lysine 6-oxidaseLOX5q23.2P28300 details
Cholesterol side-chain cleavage enzyme, mitochondrialCYP11A115q23-q24P05108 details
Inositol oxygenaseMIOX22q13.3Q9UGB7 details
4-hydroxyphenylpyruvate dioxygenaseHPD12q24-qterP32754 details
Homogentisate 1,2-dioxygenaseHGD3q13.33Q93099 details
Nitric oxide synthase, inducibleNOS217q11.2-q12P35228 details
Nitric oxide synthase, brainNOS112q24.2-q24.31P29475 details
Nitric oxide synthase, endothelialNOS37q36P29474 details
Cysteine dioxygenase type 1CDO15q23.2Q16878 details
Arachidonate 5-lipoxygenaseALOX510q11.2P09917 details
Arachidonate 15-lipoxygenase BALOX15B17p13.1O15296 details
Arachidonate 12-lipoxygenase, 12S-typeALOX1217p13.1P18054 details
Prostaglandin G/H synthase 2PTGS21q25.2-q25.3P35354 details
Prostaglandin G/H synthase 1PTGS19q32-q33.3P23219 details
Arachidonate 15-lipoxygenaseALOX1517p13.3P16050 details
Leukotriene-B(4) omega-hydroxylase 1CYP4F219p13.12P78329 details
Leukotriene-B(4) omega-hydroxylase 2CYP4F319p13.2Q08477 details
Cytochrome P450 3A4CYP3A47q21.1P08684 details
Cytochrome P450 2C9CYP2C910q24P11712 details
Sterol 26-hydroxylase, mitochondrialCYP27A12q33-qterQ02318 details
Cytochrome P450 2C19CYP2C1910q24P33261 details
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialCYP27B112q13.1-q13.3O15528 details
Steroid 17-alpha-hydroxylase/17,20 lyaseCYP17A110q24.3P05093 details
Sulfite oxidase, mitochondrialSUOX12q13.2P51687 details
3-hydroxyanthranilate 3,4-dioxygenaseHAAO2p21P46952 details
Cytochrome P450 2E1CYP2E110q24.3-qterP05181 details
Cytochrome P450 4F11CYP4F1119p13.1Q9HBI6 details
Cytochrome P450 3A43CYP3A437q21.1Q9HB55 details
Cytochrome P450 1B1CYP1B12p22.2Q16678 details
Cytochrome P450 2D6CYP2D622q13.1P10635 details
Cytochrome P450 2C18CYP2C1810q24P33260 details
Cytochrome P450 4F12CYP4F1219p13.1Q9HCS2 details
Cytochrome P450 2F1CYP2F119q13.2P24903 details
Cytochrome P450 4X1CYP4X11Q8N118 details
Cytochrome P450 2B6CYP2B619q13.2P20813 details
Cytochrome P450 3A5CYP3A57q21.1P20815 details
Cytochrome P450 1A1CYP1A115q24.1P04798 details
Cytochrome P450 2A13CYP2A1319q13.2Q16696 details
Cytochrome P450 3A7CYP3A77q21-q22.1P24462 details
Cytochrome P450 4B1CYP4B11p34-p12P13584 details
Cytochrome P450 4Z1CYP4Z11p33Q86W10 details
Cytochrome P450 1A2CYP1A215q24.1P05177 details
Cytochrome P450 19A1CYP19A115q21.1P11511 details
Cytochrome P450 2C8CYP2C810q23.33P10632 details
Cytochrome P450 2S1CYP2S119q13.1Q96SQ9 details
Cytochrome P450 4F8CYP4F819p13.1P98187 details
Cytochrome P450 2J2CYP2J21p31.3-p31.2P51589 details
Cytochrome P450 2A7CYP2A719q13.2P20853 details
Cytochrome P450 2A6CYP2A619q13.2P11509 details
Beta,beta-carotene 15,15'-monooxygenaseBCMO116q23.2Q9HAY6 details
CatalaseCAT11p13P04040 details
Hemoglobin subunit betaHBB11p15.5P68871 details
Hemoglobin subunit alphaHBA116p13.3P69905 details
25-hydroxycholesterol 7-alpha-hydroxylaseCYP7B18q21.3O75881 details
Cytochrome c oxidase subunit 1MT-CO1P00395 details
Ubiquinone biosynthesis protein COQ7 homologCOQ7Q99807 details
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialCYP24A120q13Q07973 details
Superoxide dismutase [Mn], mitochondrialSOD26q25.3P04179 details
Superoxide dismutase [Cu-Zn]SOD121q22.11P00441 details
MyoglobinMB22q13.1P02144 details
Vitamin D 25-hydroxylaseCYP2R111p15.2Q6VVX0 details
Hemoglobin subunit gamma-2HBG211p15.5P69892 details
Cholesterol 25-hydroxylaseCH25H10q23O95992 details
Dual oxidase 2DUOX215q15.3Q9NRD8 details
Extracellular superoxide dismutase [Cu-Zn]SOD34p15.2P08294 details
Trimethyllysine dioxygenase, mitochondrialTMLHEXq28Q9NVH6 details
Cholesterol 24-hydroxylaseCYP46A114q32.1Q9Y6A2 details
Cytochrome P450 11B2, mitochondrialCYP11B28q21-q22P19099 details
Tryptophan 2,3-dioxygenaseTDO24q31-q32P48775 details
24-hydroxycholesterol 7-alpha-hydroxylaseCYP39A16p21.1-p11.2Q9NYL5 details
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylaseCYP8B13p22.1Q9UNU6 details
Cytochrome c oxidase subunit 2MT-CO2P00403 details
Dual oxidase 1DUOX115q15.3Q9NRD9 details
Cytochrome P450 4A22CYP4A221p33Q5TCH4 details
Stearoyl-CoA desaturase 5SCD54q21.22Q86SK9 details
Indoleamine 2,3-dioxygenase 2IDO28p11.21Q6ZQW0 details
Cytochrome P450, family 1, subfamily A, polypeptide 1CYP1A115q24.1A0N0X8 details
Lysyl oxidase homolog 2LOXL28p21.3Q9Y4K0 details
Protein-methionine sulfoxide oxidase MICAL1MICAL16q21Q8TDZ2 details
Protein-methionine sulfoxide oxidase MICAL2MICAL211p15.3O94851 details
Protein-methionine sulfoxide oxidase MICAL3MICAL322q11.21Q7RTP6 details
Cytochrome P450 20A1CYP20A12q33.2Q6UW02 details
Cytochrome P450 2U1CYP2U14q25Q7Z449 details
Cytochrome P450 4F22CYP4F22Q6NT55 details
CytoglobinCYGB17q25.3Q8WWM9 details
Hemoglobin subunit deltaHBD11p15.5P02042 details
NeuroglobinNGB14q24.3Q9NPG2 details
2-aminoethanethiol dioxygenaseADO10q21.3Q96SZ5 details
Beta,beta-carotene 9',10'-oxygenaseBCO211q23.1Q9BYV7 details
Ferritin heavy chainFTH111q13P02794 details
Prolyl 3-hydroxylase 1LEPRE11p34.1Q32P28 details
Prolyl 3-hydroxylase 2LEPREL13q28Q8IVL5 details
Prolyl 3-hydroxylase 3LEPREL212q13Q8IVL6 details
Prolyl 4-hydroxylase subunit alpha-3P4HA311q13.4Q7Z4N8 details
Lysine-specific demethylase 2AKDM2A11q13.2Q9Y2K7 details
Lysine-specific demethylase 2BKDM2B12q24.31Q8NHM5 details
Deoxyhypusine hydroxylaseDOHH19p13.3Q9BU89 details
Egl nine homolog 1EGLN11q42.1Q9GZT9 details
Egl nine homolog 2EGLN219q13.2Q96KS0 details
Egl nine homolog 3EGLN314q13.1Q9H6Z9 details
Transmembrane prolyl 4-hydroxylaseP4HTM3p21.3Q9NXG6 details
Cytochrome P450, family 21, subfamily A, polypeptide 2CYP21A26p21.3Q08AG9 details
CP proteinCP3q23-q25A5PL27 details
NOS1 mutantNOS112q24.2-q24.31B3VK56 details
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenaseADI12p25.3Q9BV57 details
Lysine-specific demethylase 8KDM816p12.1Q8N371 details
PirinPIRXp22.2O00625 details
Methylcytosine dioxygenase TET2TET24q24Q6N021 details
Methylcytosine dioxygenase TET3TET32p13.1O43151 details
Receptors
Protein NameGene NameLocusUniprot IDDetails
Tyrosine 3-monooxygenaseTH11p15.5P07101 details
Amiloride-sensitive amine oxidase [copper-containing]ABP17q36.1P19801 details
Nitric oxide synthase, brainNOS112q24.2-q24.31P29475 details
Prostaglandin G/H synthase 1PTGS19q32-q33.3P23219 details
25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialCYP27B112q13.1-q13.3O15528 details
25-hydroxycholesterol 7-alpha-hydroxylaseCYP7B18q21.3O75881 details
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialCYP24A120q13Q07973 details
Superoxide dismutase [Cu-Zn]SOD121q22.11P00441 details
Lysyl oxidase homolog 2LOXL28p21.3Q9Y4K0 details
Egl nine homolog 2EGLN219q13.2Q96KS0 details
Transcriptional Factors
Protein NameGene NameLocusUniprot IDDetails
Heme oxygenase 1HMOX122q13.1P09601 details
Nitric oxide synthase, brainNOS112q24.2-q24.31P29475 details
Aspartyl/asparaginyl beta-hydroxylaseASPH8q12.1Q12797 details
Hypoxia-inducible factor 1-alpha inhibitorHIF1AN10q24Q9NWT6 details
CatalaseCAT11p13P04040 details
Superoxide dismutase [Mn], mitochondrialSOD26q25.3P04179 details
Lysyl oxidase homolog 2LOXL28p21.3Q9Y4K0 details
Lysine-specific demethylase 2AKDM2A11q13.2Q9Y2K7 details
Lysine-specific demethylase 2BKDM2B12q24.31Q8NHM5 details
Egl nine homolog 1EGLN11q42.1Q9GZT9 details
Egl nine homolog 2EGLN219q13.2Q96KS0 details
Egl nine homolog 3EGLN314q13.1Q9H6Z9 details
Lysine-specific demethylase 8KDM816p12.1Q8N371 details
Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66NO6614q24.3Q9H6W3 details
Histone lysine demethylase PHF8PHF8Xp11.22Q9UPP1 details
PirinPIRXp22.2O00625 details
Methylcytosine dioxygenase TET1TET110q21Q8NFU7 details
Concentrations Data
Not Available
HMDB IDHMDB0001377
DrugBank IDDB09140
Phenol Explorer Compound IDNot Available
FoodDB IDFDB022589
KNApSAcK IDNot Available
Chemspider ID952
KEGG Compound IDC00007
BioCyc IDOXYGEN-MOLECULE
BiGG ID33493
Wikipedia LinkOxygen
METLIN ID3195
PubChem Compound977
PDB IDNot Available
ChEBI ID15379
References
General ReferencesNot Available

Only showing the first 10 proteins. There are 318 proteins in total.

Enzymes

General function:
Involved in oxidoreductase activity
Specific function:
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.
Gene Name:
TYR
Uniprot ID:
P14679
Molecular weight:
60392.69
General function:
Involved in oxidoreductase activity
Specific function:
Metabolizes sarcosine, L-pipecolic acid and L-proline.
Gene Name:
PIPOX
Uniprot ID:
Q9P0Z9
Molecular weight:
44065.515
General function:
Amino acid transport and metabolism
Specific function:
Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
Gene Name:
PAOX
Uniprot ID:
Q6QHF9
Molecular weight:
55512.64
General function:
Involved in oxidoreductase activity
Specific function:
Not Available
Gene Name:
AOX1
Uniprot ID:
Q06278
Molecular weight:
147916.735
General function:
Involved in iron ion binding
Specific function:
Catalyzes a dehydrogenation to introduce C5-6 double bond into lathosterol.
Gene Name:
SC5DL
Uniprot ID:
O75845
Molecular weight:
35300.55
General function:
Involved in flavin-containing monooxygenase activity
Specific function:
In contrast with other forms of FMO it does not seem to be a drug-metabolizing enzyme.
Gene Name:
FMO5
Uniprot ID:
P49326
Molecular weight:
32480.04
General function:
Involved in acyl-CoA dehydrogenase activity
Specific function:
Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy-palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl-CoA.
Gene Name:
ACOX1
Uniprot ID:
Q15067
Molecular weight:
70135.205
General function:
Involved in D-amino-acid oxidase activity
Specific function:
Selectively catalyzes the oxidative deamination of D-aspartate and its N-methylated derivative, N-methyl D-aspartate.
Gene Name:
DDO
Uniprot ID:
Q99489
Molecular weight:
40992.53
General function:
Involved in heme oxygenase (decyclizing) activity
Specific function:
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.
Gene Name:
HMOX2
Uniprot ID:
P30519
Molecular weight:
36032.615
General function:
Involved in oxidoreductase activity
Specific function:
Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway.
Gene Name:
SQLE
Uniprot ID:
Q14534
Molecular weight:
63922.505

Transporters

General function:
Involved in oxidoreductase activity
Specific function:
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
Gene Name:
NOS2
Uniprot ID:
P35228
Molecular weight:
131116.3

Only showing the first 10 proteins. There are 318 proteins in total.