Identification
HMDB Protein ID CDBP00638
Secondary Accession Numbers Not Available
Name Pyridoxine-5'-phosphate oxidase
Description Not Available
Synonyms
  1. Pyridoxamine-phosphate oxidase
Gene Name PNPO
Protein Type Enzyme
Biological Properties
General Function Involved in pyridoxamine-phosphate oxidase activity
Specific Function Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
GO Classification
Biological Process
pyridoxine biosynthetic process
vitamin B6 metabolic process
Cellular Component
cytosol
Function
binding
nucleotide binding
catalytic activity
oxidoreductase activity, acting on the ch-nh2 group of donors
oxidoreductase activity, acting on the ch-nh2 group of donors, oxygen as acceptor
pyridoxamine-phosphate oxidase activity
fmn binding
oxidoreductase activity
Molecular Function
FMN binding
pyridoxamine-phosphate oxidase activity
Process
metabolic process
small molecule metabolic process
vitamin metabolic process
water-soluble vitamin metabolic process
vitamin b6 metabolic process
pyridoxine metabolic process
pyridoxine biosynthetic process
oxidation reduction
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location 17
Locus 17q21.32
SNPs PNPO
Gene Sequence
>786 bp
ATGACGTGCTGGCTGCGGGGCGTCACGGCGACGTTCGGGCGACCTGCCGAGTGGCCAGGC
TACCTCAGTCACCTGTGTGGTCGCAGTGCTGCCATGGACCTGGGACCCATGCGCAAGAGT
TACCGCGGGGACCGAGAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAAA
CAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTGTCCTGACATAGGGGAAGCCAATGCC
ATGTGTCTGGCTACCTGCACCAGAGATGGAAAACCCTCTGCTCGCATGTTGCTGCTGAAG
GGCTTCGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGAG
CTGGACTCTAATCCCTTTGCTTCCCTTGTCTTCTACTGGGAGCCACTTAACCGTCAGGTG
CGTGTGGAAGGCCCTGTGAAGAAACTGCCTGAGGAGGAGGCTGAGTGCTACTTCCACTCC
CGCCCCAAGAGCAGCCAGATTGGGGCTGTGGTCAGCCACCAGAGTTCTGTGATCCCTGAT
CGGGAGTATCTGAGAAAGAAAAATGAGGAACTGGAACAGCTCTACCAGGATCAAGAGGTG
CCCAAGCCAAAATCCTGGGGTGGCTATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAA
GGTCAAACCAACCGCCTGCATGACCGGATAGTCTTTCGGCGGGGCCTACCCACAGGAGAT
TCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGACTGGCTCTATGAGAGACTTGCA
CCTTAA
Protein Properties
Number of Residues 261
Molecular Weight 29987.79
Theoretical pI 7.071
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Pyridoxine-5'-phosphate oxidase
MTCWLRGVTATFGRPAEWPGYLSHLCGRSAAMDLGPMRKSYRGDREAFEETHLTSLDPVK
QFAAWFEEAVQCPDIGEANAMCLATCTRDGKPSARMLLLKGFGKDGFRFFTNFESRKGKE
LDSNPFASLVFYWEPLNRQVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPD
REYLRKKNEELEQLYQDQEVPKPKSWGGYVLYPQVMEFWQGQTNRLHDRIVFRRGLPTGD
SPLGPMTHRGEEDWLYERLAP
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q9NVS9
UniProtKB/Swiss-Prot Entry Name PNPO_HUMAN
PDB IDs
GenBank Gene ID AF468030
GeneCard ID PNPO
GenAtlas ID PNPO
HGNC ID HGNC:30260
References
General References Not Available