Showing Protein Cysteine dioxygenase type 1 (CDBP00891)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 4 compounds
Identification
HMDB Protein ID CDBP00891
Secondary Accession Numbers Not Available
Name Cysteine dioxygenase type 1
Description Not Available
Synonyms
  1. CDO
  2. CDO-I
  3. Cysteine dioxygenase type I
Gene Name CDO1
Protein Type Enzyme
Biological Properties
General Function Involved in iron ion binding
Specific Function Initiates several important metabolic pathways related to pyruvate and several sulfurate compounds including sulfate, hypotaurine and taurine. Critical regulator of cellular cysteine concentrations. Has an important role in maintaining the hepatic concentation of intracellular free cysteine within a proper narrow range.
GO Classification
Biological Process
inflammatory response
response to ethanol
response to glucocorticoid stimulus
lactation
response to cAMP
L-cysteine catabolic process
cellular nitrogen compound metabolic process
response to amino acid stimulus
cysteine metabolic process
response to glucagon stimulus
sulfur amino acid biosynthetic process
sulfur amino acid catabolic process
taurine biosynthetic process
Cellular Component
cytosol
Function
cysteine dioxygenase activity
oxidoreductase activity
ion binding
cation binding
metal ion binding
binding
catalytic activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
transition metal ion binding
iron ion binding
Molecular Function
ferrous iron binding
cysteine dioxygenase activity
Process
metabolic process
cysteine metabolic process
l-cysteine metabolic process
cellular metabolic process
sulfur amino acid metabolic process
oxidation reduction
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location 5
Locus 5q23.2
SNPs CDO1
Gene Sequence 
>603 bp
ATGGAACAGACCGAAGTGCTGAAGCCACGGACCCTGGCTGATCTGATCCGCATCCTGCAC
CAGCTCTTTGCCGGCGATGAGGTCAATGTAGAGGAGGTGCAGGCCATCATGGAAGCCTAC
GAGAGCGACCCCATCGAGTGGGCAATGTACGCCAAGTTCGACCAGTACAGGTATACCCGA
AATCTTGTGGATCAAGGAAATGGAAAATTTAATCTGATGATTCTCTGTTGGGGTGAAGGA
CATGGCAGCAGTATTCATGATCATACCAACTCCCACTGCTTTCTGAAGATGCTACAGGGA
AATCTAAAGGAGACATTATTTGCCTGGCCTGACAAAAAATCCAATGAGATGGTCAAGAAG
TCTGAAAGAGTCTTGAGGGAAAACCAGTGTGCCTACATCAATGATTCCATTGGCTTACAT
CGAGTAGAGAACATCAGCCATACGGAACCTGCTGTGAGCCTTCACTTGTACAGTCCACCT
TTTGATACATGCCATGCCTTTGATCAAAGAACAGGACATAAAAACAAAGTCACAATGACA
TTCCATAGTAAATTTGGAATCAGAACTCCAAATGCAACTTCGGGCTCGCTGGAGAACAAC
TAA
Protein Properties
Number of Residues 200
Molecular Weight 22971.745
Theoretical pI 6.591
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence 
>Cysteine dioxygenase type 1
MEQTEVLKPRTLADLIRILHQLFAGDEVNVEEVQAIMEAYESDPTEWAMYAKFDQYRYTR
NLVDQGNGKFNLMILCWGEGHGSSIHDHTNSHCFLKMLQGNLKETLFAWPDKKSNEMVKK
SERVLRENQCAYINDSIGLHRVENISHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMT
FHSKFGIRTPNATSGSLENN
GenBank ID Protein 467561
UniProtKB/Swiss-Prot ID Q16878
UniProtKB/Swiss-Prot Entry Name CDO1_HUMAN
PDB IDs
GenBank Gene ID Z31357
GeneCard ID CDO1
GenAtlas ID CDO1
HGNC ID HGNC:1795
References
General References Not Available