Cannabis Compound Database: Showing Protein Cysteine dioxygenase type 1 (CDBP00891)

Identification Biological properties Gene properties Protein properties External links References XML Show 4 compounds

Identification

HMDB Protein ID

CDBP00891

Secondary Accession Numbers

Not Available

Name

Cysteine dioxygenase type 1

Description

Not Available

Synonyms

CDO
CDO-I
Cysteine dioxygenase type I

Gene Name

CDO1

Protein Type

Enzyme

Biological Properties

General Function

Involved in iron ion binding

Specific Function

Initiates several important metabolic pathways related to pyruvate and several sulfurate compounds including sulfate, hypotaurine and taurine. Critical regulator of cellular cysteine concentrations. Has an important role in maintaining the hepatic concentation of intracellular free cysteine within a proper narrow range.

GO Classification

Biological Process
sulfur amino acid biosynthetic process
sulfur amino acid catabolic process
taurine biosynthetic process
inflammatory response
response to ethanol
response to glucocorticoid stimulus
lactation
response to cAMP
L-cysteine catabolic process
cellular nitrogen compound metabolic process
response to amino acid stimulus
cysteine metabolic process
response to glucagon stimulus
Cellular Component
cytosol
Function
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
transition metal ion binding
iron ion binding
cysteine dioxygenase activity
oxidoreductase activity
ion binding
cation binding
metal ion binding
binding
catalytic activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
Molecular Function
ferrous iron binding
cysteine dioxygenase activity
Process
metabolic process
cysteine metabolic process
l-cysteine metabolic process
cellular metabolic process
sulfur amino acid metabolic process
oxidation reduction
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process

Cellular Location

Not Available

Pathways

Name	SMPDB/Pathwhiz	KEGG
Cysteine Metabolism
Taurine and Hypotaurine Metabolism
taurine biosynthesis	Not Available	Not Available
Cysteine and methionine metabolism	Not Available
Beta-mercaptolactate-cysteine disulfiduria		Not Available

Gene Properties

Chromosome Location

Locus

5q23.2

SNPs

CDO1

Gene Sequence

>603 bp
ATGGAACAGACCGAAGTGCTGAAGCCACGGACCCTGGCTGATCTGATCCGCATCCTGCAC
CAGCTCTTTGCCGGCGATGAGGTCAATGTAGAGGAGGTGCAGGCCATCATGGAAGCCTAC
GAGAGCGACCCCATCGAGTGGGCAATGTACGCCAAGTTCGACCAGTACAGGTATACCCGA
AATCTTGTGGATCAAGGAAATGGAAAATTTAATCTGATGATTCTCTGTTGGGGTGAAGGA
CATGGCAGCAGTATTCATGATCATACCAACTCCCACTGCTTTCTGAAGATGCTACAGGGA
AATCTAAAGGAGACATTATTTGCCTGGCCTGACAAAAAATCCAATGAGATGGTCAAGAAG
TCTGAAAGAGTCTTGAGGGAAAACCAGTGTGCCTACATCAATGATTCCATTGGCTTACAT
CGAGTAGAGAACATCAGCCATACGGAACCTGCTGTGAGCCTTCACTTGTACAGTCCACCT
TTTGATACATGCCATGCCTTTGATCAAAGAACAGGACATAAAAACAAAGTCACAATGACA
TTCCATAGTAAATTTGGAATCAGAACTCCAAATGCAACTTCGGGCTCGCTGGAGAACAAC
TAA

Protein Properties

Number of Residues

200

Molecular Weight

22971.745

Theoretical pI

6.591

Pfam Domain Function

CDO_I (PF05995 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Cysteine dioxygenase type 1
MEQTEVLKPRTLADLIRILHQLFAGDEVNVEEVQAIMEAYESDPTEWAMYAKFDQYRYTR
NLVDQGNGKFNLMILCWGEGHGSSIHDHTNSHCFLKMLQGNLKETLFAWPDKKSNEMVKK
SERVLRENQCAYINDSIGLHRVENISHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKVTMT
FHSKFGIRTPNATSGSLENN

External Links

GenBank ID Protein

467561

UniProtKB/Swiss-Prot ID

Q16878

UniProtKB/Swiss-Prot Entry Name

CDO1_HUMAN

PDB IDs