<?xml version="1.0" encoding="UTF-8"?>
<protein>
  <id type="integer">892</id>
  <cancdbp-id>CDBP00891</cancdbp-id>
  <name>Cysteine dioxygenase type 1</name>
  <uniprot-id>Q16878</uniprot-id>
  <uniprot-name>CDO1_HUMAN</uniprot-name>
  <enzyme type="boolean">true</enzyme>
  <transporter type="boolean">false</transporter>
  <protein-type>Enzyme</protein-type>
  <organism>Homo_sapiens</organism>
  <gene-name>CDO1</gene-name>
  <num-residues type="integer">200</num-residues>
  <molecular-weight type="decimal">22971.745</molecular-weight>
  <theoretical-pi type="decimal">6.591</theoretical-pi>
  <general-function>Involved in iron ion binding</general-function>
  <specific-function>Initiates several important metabolic pathways related to pyruvate and several sulfurate compounds including sulfate, hypotaurine and taurine. Critical regulator of cellular cysteine concentrations. Has an important role in maintaining the hepatic concentation of intracellular free cysteine within a proper narrow range.
</specific-function>
  <signal-regions type="array"/>
  <transmembrane-regions type="array"/>
  <pdb-ids>2IC1</pdb-ids>
  <genbank-gene-id>Z31357</genbank-gene-id>
  <genbank-protein-id>467561</genbank-protein-id>
  <genecard-id>CDO1</genecard-id>
  <chromosome-location>5</chromosome-location>
  <locus>5q23.2</locus>
  <geneatlas-id>CDO1</geneatlas-id>
  <hgnc-id>HGNC:1795</hgnc-id>
  <export type="boolean">true</export>
  <comment nil="true"/>
  <kegg-id>hsa:1036</kegg-id>
  <meta-cyc-id></meta-cyc-id>
  <ncbi-sequence-ids>NP_001792.2:NM_001801.2</ncbi-sequence-ids>
  <tissue-specificity>Highly expressed in liver and placenta. Low expression in heart, brain and pancreas. Also detected in hepatoblastoma Hep-G2 cells.
</tissue-specificity>
  <cofactor>iron ion . Zinc to a much lesser extent</cofactor>
  <subunit>Monomer
</subunit>
  <cellular-location nil="true"/>
  <ec-number nil="true"/>
  <created-at type="dateTime">2020-06-12T23:06:52Z</created-at>
  <updated-at type="dateTime">2020-07-28T02:26:08Z</updated-at>
  <description nil="true"/>
  <receptor type="integer">0</receptor>
  <metal-binding type="integer">1</metal-binding>
  <trans-factor type="integer">0</trans-factor>
</protein>

