Identification
HMDB Protein ID CDBP02490
Secondary Accession Numbers Not Available
Name Cytochrome c oxidase subunit 6A1, mitochondrial
Description Not Available
Synonyms
  1. COX VIa-L
  2. Cytochrome c oxidase polypeptide VIa-liver
  3. Cytochrome c oxidase subunit VIA-liver
Gene Name COX6A1
Protein Type Enzyme
Biological Properties
General Function Involved in cytochrome-c oxidase activity
Specific Function This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport
GO Classification
Component
mitochondrial inner membrane
mitochondrial membrane part
mitochondrial respiratory chain complex iv
membrane
cell part
membrane part
organelle membrane
organelle inner membrane
Function
catalytic activity
oxidoreductase activity
heme-copper terminal oxidase activity
cytochrome-c oxidase activity
Cellular Location
  1. Mitochondrion inner membrane
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 12q24.2|12q24.2
SNPs COX6A1
Gene Sequence
>330 bp
ATGGCGGTAGTTGGTGTGTCCTCGGTTTCTCGGCTGCTGGGTCGGTCCCGCCCACAGCTG
GGGCGGCCTATGTCGAGTGGCGCCCATGGCGAAGAGGGCTCAGCTCGCATGTGGAAGACT
CTCACCTTCTTCGTCGCGCTCCCCGGGGTGGCAGTCAGCATGCTGAATGTGTACCTGAAG
TCGCACCACGGAGAGCACGAGAGACCCGAGTTCATCGCCTACCCCCATCTCCGCATCAGG
ACCAAGCCGTTTCCCTGGGGAGATGGTAACCATACTCTATTCCATAACCCTCATGTGAAT
CCACTTCCAACTGGCTACGAAGATGAATAA
Protein Properties
Number of Residues 109
Molecular Weight 12154.8
Theoretical pI 9.7
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Cytochrome c oxidase subunit 6A1, mitochondrial
MAVVGVSSVSRLLGRSRPQLGRPMSSGAHGEEGSARMWKTLTFFVALPGVAVSMLNVYLK
SHHGEHERPEFIAYPHLRIRTKPFPWGDGNHTLFHNPHVNPLPTGYEDE
GenBank ID Protein 189065224
UniProtKB/Swiss-Prot ID P12074
UniProtKB/Swiss-Prot Entry Name CX6A1_HUMAN
PDB IDs Not Available
GenBank Gene ID AK312009
GeneCard ID COX6A1
GenAtlas ID COX6A1
HGNC ID HGNC:2277
References
General References Not Available