| Identification |
|---|
| HMDB Protein ID
| CDBP03845 |
| Secondary Accession Numbers
| Not Available |
| Name
| Cytochrome P450 20A1 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| CYP20A1 |
| Protein Type
| Metal Binding |
| Biological Properties |
|---|
| General Function
| Involved in monooxygenase activity |
| Specific Function
| Not Available |
| GO Classification
|
| Cellular Component |
| integral to membrane |
| Function |
| heme binding |
| oxidoreductase activity |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| catalytic activity |
| transition metal ion binding |
| electron carrier activity |
| iron ion binding |
| monooxygenase activity |
| Molecular Function |
| electron carrier activity |
| monooxygenase activity |
| iron ion binding |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| heme binding |
| Process |
| metabolic process |
| oxidation reduction |
|
| Cellular Location
|
- Membrane
- Single-pass membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 2 |
| Locus
| 2q33.2 |
| SNPs
| CYP20A1 |
| Gene Sequence
|
>1389 bp
ATGTTGGACTTCGCGATCTTCGCCGTTACCTTCTTGCTGGCGTTGGTGGGAGCCGTGCTC
TACCTCTATCCGGCTTCCAGACAAGCTGCAGGAATTCCAGGGATTACTCCAACTGAAGAA
AAAGATGGTAATCTTCCAGATATTGTGAATAGTGGAAGTTTGCATGAGTTCCTGGTTAAT
TTGCATGAGAGATATGGGCCTGTGGTCTCCTTCTGGTTTGGCAGGCGCCTCGTGGTTAGT
TTGGGCACTGTTGATGTACTGAAGCAGCATATCAATCCCAATAAGACATCGGACCCTTTT
GAAACCATGCTGAAGTCATTATTAAGGTATCAATCTGGTGGTGGCAGTGTGAGTGAAAAC
CACATGAGGAAAAAATTGTATGAAAATGGTGTGACTGATTCTCTGAAGAGTAACTTTGCC
CTCCTCCTAAAGCTTTCAGAAGAATTATTAGATAAATGGCTCTCCTACCCAGAGACCCAG
CACGTGCCCCTCAGCCAGCATATGCTTGGTTTTGCTATGAAGTCTGTTACACAGATGGTA
ATGGGTAGTACATTTGAAGATGATCAGGAAGTCATTCGCTTCCAGAAGAATCATGGCACA
GTTTGGTCTGAGATTGGAAAAGGCTTTCTAGATGGGTCACTTGATAAAAACATGACTCGG
AAAAAACAATATGAAGATGCCCTCATGCAACTGGAGTCTGTTTTAAGGAACATCATAAAA
GAACGAAAAGGAAGGAACTTCAGTCAACATATTTTCATTGACTCCTTAGTACAAGGGAAC
CTTAATGACCAACAGATCCTAGAAGACAGTATGATATTTTCTCTGGCCAGTTGCATAATA
ACTGCAAAATTGTGTACCTGGGCAATCTGTTTTTTAACCACCTCTGAAGAAGTTCAAAAA
AAATTATATGAAGAGATAAACCAAGTTTTTGGAAATGGTCCTGTTACTCCAGAGAAAATT
GAGCAGCTCAGATATTGTCAGCATGTGCTTTGTGAAACTGTTCGAACTGCCAAACTGACT
CCAGTTTCTGCCCAGCTTCAAGATATTGAAGGAAAAATTGACCGATTTATTATTCCTAGA
GAGACCCTCGTCCTTTATGCCCTTGGTGTGGTACTTCAGGATCCTAATACTTGGCCATCT
CCACACAAGTTTGATCCAGATCGGTTTGATGATGAATTAGTAATGAAAACTTTTTCCTCA
CTTGGATTCTCAGGCACACAGGAGTGTCCAGAGTTGAGGTTTGCATATATGGTGACCACA
GTACTTCTTAGTGTATTGGTGAAGAGACTGCACCTACTTTCTGTGGAGGGACAGGTTATT
GAAACAAAGTATGAACTGGTAACATCATCAAGGGAAGAAGCTTGGATCACTGTCTCAAAG
AGATATTAA
|
| Protein Properties |
|---|
| Number of Residues
| 462 |
| Molecular Weight
| 52431.955 |
| Theoretical pI
| 6.219 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Cytochrome P450 20A1
MLDFAIFAVTFLLALVGAVLYLYPASRQAAGIPGITPTEEKDGNLPDIVNSGSLHEFLVN
LHERYGPVVSFWFGRRLVVSLGTVDVLKQHINPNKTSDPFETMLKSLLRYQSGGGSVSEN
HMRKKLYENGVTDSLKSNFALLLKLSEELLDKWLSYPETQHVPLSQHMLGFAMKSVTQMV
MGSTFEDDQEVIRFQKNHGTVWSEIGKGFLDGSLDKNMTRKKQYEDALMQLESVLRNIIK
ERKGRNFSQHIFIDSLVQGNLNDQQILEDSMIFSLASCIITAKLCTWAICFLTTSEEVQK
KLYEEINQVFGNGPVTPEKIEQLRYCQHVLCETVRTAKLTPVSAQLQDIEGKIDRFIIPR
ETLVLYALGVVLQDPNTWPSPHKFDPDRFDDELVMKTFSSLGFSGTQECPELRFAYMVTT
VLLSVLVKRLHLLSVEGQVIETKYELVTSSREEAWITVSKRY
|
| External Links |
|---|
| GenBank ID Protein
| 29171730 |
| UniProtKB/Swiss-Prot ID
| Q6UW02 |
| UniProtKB/Swiss-Prot Entry Name
| CP20A_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_177538.2 |
| GeneCard ID
| CYP20A1 |
| GenAtlas ID
| CYP20A1 |
| HGNC ID
| HGNC:20576 |
| References |
|---|
| General References
| Not Available |