Record Information
Version1.0
Created at2020-04-17 19:14:04 UTC
Updated at2020-11-18 16:39:26 UTC
CannabisDB IDCDB005147
Secondary Accession NumbersNot Available
Cannabis Compound Identification
Common NameUridine 5'-diphosphate
DescriptionUridine 5'-diphosphate, also known as 5'-UDP or uridine diphosphoric acid, belongs to the class of organic compounds known as pyrimidine ribonucleoside diphosphates. These are pyrimidine ribonucleotides with diphosphate group linked to the ribose moiety. Uridine 5'-diphosphate is an important extracellular pyrimidine signaling molecule that mediates diverse biological effects via P1 and P2 purinergic receptors, such as the uptake of thymidine and proliferation of gliomas. Uridine 5'-diphosphate is an extremely weak basic (essentially neutral) compound (based on its pKa). Uridine 5'-diphosphate exists in all living species, ranging from bacteria to humans. Within humans, uridine 5'-diphosphate participates in a number of enzymatic reactions. In particular, tamoxifen-N-glucuronide and uridine 5'-diphosphate can be biosynthesized from tamoxifen and uridine diphosphate glucuronic acid through the action of the enzyme UDP-glucuronosyltransferase 1-4. In addition, 4-hydroxytamoxifen-O-glucuronide and uridine 5'-diphosphate can be biosynthesized from 4-hydroxytamoxifen and uridine diphosphate glucuronic acid through the action of the enzyme UDP-glucuronosyltransferase 1-4. In humans, uridine 5'-diphosphate is involved in tamoxifen metabolism pathway. Outside of the human body, Uridine 5'-diphosphate has been detected, but not quantified in, several different foods, such as pineapples, pine nuts, potato, swiss chards, and lima beans. This could make uridine 5'-diphosphate a potential biomarker for the consumption of these foods. Uridine 5'-diphosphate induces intracellular Ca(2+) responses and oscillations in HeLa cells, due to the activation of P2Ys (G-protein coupled ATP receptors). Uridine 5'-diphosphate is expected to be in Cannabis as all living plants are known to produce and metabolize it.
Structure
Thumb
Synonyms
ValueSource
Uridine diphosphateChEBI
Uridine diphosphoric acidGenerator
Uridine 5'-diphosphoric acidGenerator
5'-UDPHMDB
UDPHMDB
Uridine 5'-pyrophosphateHMDB
Uridine 5'-pyrophosphorateHMDB
Uridine 5'-pyrophosphoric acidHMDB
Uridine pyrophosphateHMDB
Pyrophosphate, uridineHMDB
Diphosphate, uridineHMDB
5’-UDPHMDB
Uridine 5'-(trihydrogen pyrophosphate)HMDB
Uridine 5'-diphosphateHMDB
Uridine 5’-(trihydrogen pyrophosphate)HMDB
Uridine 5’-diphosphateHMDB
Uridine 5’-diphosphoric acidHMDB
Uridine 5’-pyrophosphateHMDB
Uridine 5’-pyrophosphoric acidHMDB
Chemical FormulaC9H14N2O12P2
Average Molecular Weight404.16
Monoisotopic Molecular Weight404.0022
IUPAC Name[({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid
Traditional NameUDP
CAS Registry Number58-98-0
SMILES
O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(O)=O)N1C=CC(=O)NC1=O
InChI Identifier
InChI=1S/C9H14N2O12P2/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChI KeyXCCTYIAWTASOJW-XVFCMESISA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as pyrimidine ribonucleoside diphosphates. These are pyrimidine ribonucleotides with diphosphate group linked to the ribose moiety.
KingdomOrganic compounds
Super ClassNucleosides, nucleotides, and analogues
ClassPyrimidine nucleotides
Sub ClassPyrimidine ribonucleotides
Direct ParentPyrimidine ribonucleoside diphosphates
Alternative Parents
Substituents
  • Pyrimidine ribonucleoside diphosphate
  • Pentose phosphate
  • Pentose-5-phosphate
  • Glycosyl compound
  • N-glycosyl compound
  • Monosaccharide phosphate
  • Organic pyrophosphate
  • Hydroxypyrimidine
  • Pyrimidone
  • Monoalkyl phosphate
  • Hydropyrimidine
  • Monosaccharide
  • Organic phosphoric acid derivative
  • Phosphoric acid ester
  • Pyrimidine
  • Alkyl phosphate
  • Heteroaromatic compound
  • Tetrahydrofuran
  • Secondary alcohol
  • 1,2-diol
  • Oxacycle
  • Azacycle
  • Organoheterocyclic compound
  • Organic nitrogen compound
  • Hydrocarbon derivative
  • Organooxygen compound
  • Organonitrogen compound
  • Organic oxide
  • Alcohol
  • Organopnictogen compound
  • Organic oxygen compound
  • Aromatic heteromonocyclic compound
Molecular FrameworkAromatic heteromonocyclic compounds
External Descriptors
Ontology
Disposition

Route of exposure:

Source:

Biological location:

Role

Industrial application:

Physical Properties
StateSolid
Experimental Properties
PropertyValueReference
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
logPNot AvailableNot Available
Predicted Properties
PropertyValueSource
logP-0.94ALOGPS
logP-3ChemAxon
logS-1.7ALOGPS
pKa (Strongest Acidic)1.77ChemAxon
pKa (Strongest Basic)-3.7ChemAxon
Physiological Charge-2ChemAxon
Hydrogen Acceptor Count10ChemAxon
Hydrogen Donor Count6ChemAxon
Polar Surface Area212.39 ŲChemAxon
Rotatable Bond Count6ChemAxon
Refractivity74.31 m³·mol⁻¹ChemAxon
Polarizability30.43 ųChemAxon
Number of Rings2ChemAxon
BioavailabilityNoChemAxon
Rule of FiveNoChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Spectra
EI-MS/GC-MS
TypeDescriptionSplash KeyView
Predicted GC-MSUridine 5'-diphosphate, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positivesplash10-004i-4911000000-e0e7874495a5b5baf6b1Spectrum
Predicted GC-MSUridine 5'-diphosphate, 2 TMS, Predicted GC-MS Spectrum - 70eV, Positivesplash10-00pi-3795210000-ef08b4deabe40209df75Spectrum
MS/MS
TypeDescriptionSplash KeyView
MS/MSLC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)splash10-0002-9000000000-7c065a8df0e08b8c365fSpectrum
MS/MSLC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)splash10-0002-9000000000-73234233232c376d095cSpectrum
MS/MSLC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)splash10-0002-9000000000-7c065a8df0e08b8c365fSpectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF (UPLC Q-Tof Premier, Waters) , Negativesplash10-0pdi-6910600000-bf4136774851b6559f17Spectrum
MS/MSLC-MS/MS Spectrum - LC-ESI-QTOF , negativesplash10-0pdi-6910600000-bf4136774851b6559f17Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-03di-1901000000-4c9ba16543da8ee18c74Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-03di-4901000000-1ff9973ec00da457d453Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-03di-7900000000-f88f01d934d46a57fefbSpectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-0ik9-3904300000-454bc02fb8862a1d0facSpectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-057l-9801000000-5aabcad933dc7e5003a8Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-004i-9100000000-7a6d480c699f409f2f36Spectrum
NMR
TypeDescriptionView
1D NMR1H NMR SpectrumSpectrum
1D NMR1H NMR SpectrumSpectrum
1D NMR13C NMR SpectrumSpectrum
2D NMR[1H,13C] 2D NMR SpectrumSpectrum
Pathways
Pathways
Protein Targets
Enzymes
Protein NameGene NameLocusUniprot IDDetails
UMP-CMP kinaseCMPK11p32P30085 details
Ectonucleoside triphosphate diphosphohydrolase 1ENTPD110q24P49961 details
Soluble calcium-activated nucleotidase 1CANT117q25.3Q8WVQ1 details
Ectonucleoside triphosphate diphosphohydrolase 3ENTPD33p21.3O75355 details
Uridine-cytidine kinase 1UCK19q34.13Q9HA47 details
Nucleoside diphosphate kinase, mitochondrialNME416p13.3O00746 details
Ribonucleoside-diphosphate reductase large subunitRRM111p15.5P23921 details
Nucleoside diphosphate kinase ANME117q21.3P15531 details
Nucleoside diphosphate kinase 7NME71q24Q9Y5B8 details
Ribonucleoside-diphosphate reductase subunit M2RRM22p25-p24P31350 details
Nucleoside diphosphate kinase BNME217q21.3P22392 details
Nucleoside diphosphate kinase 3NME316q13.3Q13232 details
Nucleoside diphosphate kinase 6NME63p21O75414 details
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinaseGNE9p13.3Q9Y223 details
Beta-1,4-galactosyltransferase 2B4GALT21p34-p33O60909 details
Alpha-lactalbuminLALBAP00709 details
Beta-1,4-galactosyltransferase 1B4GALT19p13P15291 details
UDP-glucuronosyltransferase 2B28UGT2B284q13.2Q9BY64 details
UDP-glucuronosyltransferase 2B4UGT2B44q13P06133 details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3PLOD37q22O60568 details
Chondroitin sulfate N-acetylgalactosaminyltransferase 1CSGALNACT18p21.3Q8TDX6 details
UDP-glucuronosyltransferase 1-4UGT1A42q37P22310 details
UDP-glucuronosyltransferase 2B10UGT2B104q13.2P36537 details
UDP-glucuronosyltransferase 2B7UGT2B74q13P16662 details
UDP-glucuronosyltransferase 2B15UGT2B154q13P54855 details
UDP-glucuronosyltransferase 2A1UGT2A14q13.3Q9Y4X1 details
UDP-glucuronosyltransferase 1-1UGT1A12q37P22309 details
UDP-glucuronosyltransferase 1-9UGT1A92q37O60656 details
UDP-glucuronosyltransferase 1-8UGT1A82q37Q9HAW9 details
UDP-glucuronosyltransferase 1-3UGT1A32q37P35503 details
UDP-glucuronosyltransferase 1-10UGT1A102q37Q9HAW8 details
UDP-glucuronosyltransferase 2B17UGT2B174q13O75795 details
UDP-glucuronosyltransferase 1-6UGT1A62q37P19224 details
UDP-glucuronosyltransferase 1-5UGT1A52q37P35504 details
UDP-glucuronosyltransferase 2B11UGT2B114q13.2O75310 details
UDP-glucuronosyltransferase 1-7UGT1A72q37Q9HAW7 details
GTP:AMP phosphotransferase, mitochondrialAK39p24.1Q9UIJ7 details
6-phosphofructokinase type CPFKP10p15.3-p15.2Q01813 details
6-phosphofructokinase, liver typePFKL21q22.3P17858 details
6-phosphofructokinase, muscle typePFKM12q13.3P08237 details
Pyruvate kinase isozymes M1/M2PKM15q22P14618 details
Pyruvate kinase isozymes R/LPKLR1q21P30613 details
Ceramide glucosyltransferaseUGCG9q31Q16739 details
Beta-1,4 N-acetylgalactosaminyltransferase 1B4GALNT112q13.3Q00973 details
Lactosylceramide 4-alpha-galactosyltransferaseA4GALT22q13.2Q9NPC4 details
Ectonucleoside triphosphate diphosphohydrolase 4ENTPD48p21.3Q9Y227 details
Ectonucleoside triphosphate diphosphohydrolase 6ENTPD620p11.21O75354 details
Ectonucleoside triphosphate diphosphohydrolase 5ENTPD514q24O75356 details
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3B3GAT311q12.3O94766 details
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2B3GAT26q13Q9NPZ5 details
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1B3GAT111q25Q9P2W7 details
Phosphatidylinositol N-acetylglucosaminyltransferase subunit QPIGQ16p13.3Q9BRB3 details
Phosphatidylinositol N-acetylglucosaminyltransferase subunit APIGAXp22.1P37287 details
Phosphatidylinositol N-acetylglucosaminyltransferase subunit HPIGH14q24.1Q14442 details
Phosphatidylinositol N-acetylglucosaminyltransferase subunit PPIGP21q22.2P57054 details
Phosphatidylinositol N-acetylglucosaminyltransferase subunit CPIGC1q23-q25Q92535 details
Dolichyl-phosphate beta-glucosyltransferaseALG513q13.3Q9Y673 details
Polypeptide N-acetylgalactosaminyltransferase 11GALNT117q36.1Q8NCW6 details
Polypeptide N-acetylgalactosaminyltransferase 4GALNT412q21.33Q8N4A0 details
Polypeptide N-acetylgalactosaminyltransferase 3GALNT32q24-q31Q14435 details
Probable polypeptide N-acetylgalactosaminyltransferase 8GALNT812p13.3Q9NY28 details
Polypeptide N-acetylgalactosaminyltransferase-like protein 2GALNTL23p25.1Q8N3T1 details
Putative polypeptide N-acetylgalactosaminyltransferase-like protein 1GALNTL114q24.1Q8N428 details
Polypeptide N-acetylgalactosaminyltransferase 10GALNT105q33.2Q86SR1 details
Polypeptide N-acetylgalactosaminyltransferase 13GALNT132q24.1Q8IUC8 details
Putative polypeptide N-acetylgalactosaminyltransferase-like protein 3WBSCR177q11.23Q6IS24 details
Putative polypeptide N-acetylgalactosaminyltransferase-like protein 4GALNTL411p15.3Q6P9A2 details
N-acetylgalactosaminyltransferase 7GALNT74q31.1Q86SF2 details
Polypeptide N-acetylgalactosaminyltransferase 6GALNT612q13Q8NCL4 details
Polypeptide N-acetylgalactosaminyltransferase 14GALNT142p23.1Q96FL9 details
Polypeptide N-acetylgalactosaminyltransferase 2GALNT21q41-q42Q10471 details
Polypeptide N-acetylgalactosaminyltransferase 12GALNT129q22.33Q8IXK2 details
Polypeptide N-acetylgalactosaminyltransferase 1GALNT118q12.1Q10472 details
Polypeptide N-acetylgalactosaminyltransferase 5GALNT52q24.1Q7Z7M9 details
Beta-1,4-galactosyltransferase 3B4GALT31q21-q23O60512 details
Beta-1,4-galactosyltransferase 4B4GALT43q13.3O60513 details
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1B3GALNT13q25O75752 details
Glycogen [starch] synthase, liverGYS212p12.2P54840 details
Glycogen [starch] synthase, muscleGYS119q13.3P13807 details
Histo-blood group ABO system transferaseABO9q34.2P16442 details
2-hydroxyacylsphingosine 1-beta-galactosyltransferaseUGT84q26Q16880 details
Beta-1,3-galactosyltransferase 4B3GALT46p21.3O96024 details
Chondroitin sulfate synthase 3CHSY35q23.3Q70JA7 details
Chondroitin sulfate synthase 2CHPF2q35Q8IZ52 details
Chondroitin sulfate synthase 1CHSY115q26.3Q86X52 details
Polyribonucleotide nucleotidyltransferase 1, mitochondrialPNPT12p15Q8TCS8 details
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferaseMGAT214q21Q10469 details
Exostosin-1EXT18q24.11Q16394 details
Hyaluronan synthase 1HAS119q13.4Q92839 details
Exostosin-like 3EXTL38p21O43909 details
Exostosin-2EXT211p12-p11Q93063 details
Exostosin-like 1EXTL11p36.1Q92935 details
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferaseB3GNT111q13.2O43505 details
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase AMGAT52q21.3Q09328 details
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunitOGTXq13O15294 details
Hyaluronan synthase 3HAS316q22.1O00219 details
Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferaseMGAT322q13.1Q09327 details
Hyaluronan synthase 2HAS28q24.12Q92819 details
Uridine-cytidine kinase 2UCK21q23Q9BZX2 details
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform BGCNT26p24.2Q06430 details
Beta-1,4-galactosyltransferase 7B4GALT75q35.2-q35.3Q9UBV7 details
Chondroitin sulfate glucuronyltransferaseCHPF27q36.1Q9P2E5 details
Chondroitin sulfate N-acetylgalactosaminyltransferase 2CSGALNACT210q11.21Q8N6G5 details
ENTPD4 proteinENTPD48p21.3Q8NE73 details
Beta-1,3-N-acetylglucosaminyltransferase bGnT-2bGnT-22p15Q9NY97 details
Beta-1,3-galactosyltransferase 6B3GALT61p36.33Q96L58 details
Polypeptide N-acetylgalactosaminyltransferase 9GALNT912q24.33Q9HCQ5 details
Exostosin-like 2EXTL21p21Q9UBQ6 details
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase AMGAT4A2q12Q9UM21 details
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase BMGAT4B5q35Q9UQ53 details
Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferaseB3GNT53q28Q9BYG0 details
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1C1GALT17p21.3Q9NS00 details
Beta-1,4-galactosyltransferase 6B4GALT618q11Q9UBX8 details
UDP-glucuronosyltransferase 2A3UGT2A34q13.2Q6UWM9 details
Ribonucleoside-diphosphate reductase subunit M2 BRRM2B8q23.1Q7LG56 details
UMP-CMP kinase 2, mitochondrialCMPK22p25.2Q5EBM0 details
Uridine-cytidine kinase-like 1UCKL120q13.33Q9NWZ5 details
Ectonucleoside triphosphate diphosphohydrolase 8ENTPD89q34.3Q5MY95 details
Polypeptide N-acetylgalactosaminyltransferase-like 6GALNTL64q34.1Q49A17 details
Putative polypeptide N-acetylgalactosaminyltransferase-like protein 5GALNTL57q36.1Q7Z4T8 details
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1POMGNT11p34.1Q8WZA1 details
Beta-1,4-N-acetylgalactosaminyltransferase 3B4GALNT312p13.33Q6L9W6 details
N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1B4GALNT411p15.5Q76KP1 details
HCG2039726, isoform CRA_fUGT1A102q37Q5DT02 details
HCG2039726, isoform CRA_eUGT1A82q37Q5DSZ6 details
UDP glycosyltransferase 1 family polypeptide A7UGT1A72q37Q5DSZ7 details
Pp-GalNAc-transferase 20GALNT20Q2L4S5 details
UDP-N-acetylglucosamine transferase subunit ALG13 homologALG13Xq23Q9NP73 details
EGF domain-specific O-linked N-acetylglucosamine transferaseEOGT3p14.1Q5NDL2 details
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferaseGCNT19q13Q02742 details
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3GCNT315q21.3O95395 details
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4GCNT45q12Q9P109 details
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform AGCNT26p24.2Q8N0V5 details
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform CGCNT26p24.2Q8NFS9 details
Procollagen galactosyltransferase 1GLT25D119p13.11Q8NBJ5 details
Procollagen galactosyltransferase 2GLT25D21q25Q8IYK4 details
Glycosyltransferase-like domain-containing protein 2GTDC23p22.1Q8NAT1 details
Glucoside xylosyltransferase 1GXYLT112q12Q4G148 details
Glucoside xylosyltransferase 2GXYLT23p13A0PJZ3 details
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferaseMGAT15q35P26572 details
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase CMGAT4C12q21Q9UBM8 details
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase BMGAT5B17q25.2Q3V5L5 details
Nucleoside diphosphate kinase homolog 5NME5P56597 details
UDP-glucuronosyltransferase 3A1UGT3A15p13.2Q6NUS8 details
UDP-glucuronosyltransferase 3A2UGT3A25p13.2Q3SY77 details
Xyloside xylosyltransferase 1XXYLT13q29Q8NBI6 details
TransportersNot Available
Metal Bindings
Protein NameGene NameLocusUniprot IDDetails
Soluble calcium-activated nucleotidase 1CANT117q25.3Q8WVQ1 details
Nucleoside diphosphate kinase, mitochondrialNME416p13.3O00746 details
Nucleoside diphosphate kinase 7NME71q24Q9Y5B8 details
Ribonucleoside-diphosphate reductase subunit M2RRM22p25-p24P31350 details
Nucleoside diphosphate kinase BNME217q21.3P22392 details
Nucleoside diphosphate kinase 3NME316q13.3Q13232 details
Nucleoside diphosphate kinase 6NME63p21O75414 details
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinaseGNE9p13.3Q9Y223 details
Beta-1,4-galactosyltransferase 2B4GALT21p34-p33O60909 details
Alpha-lactalbuminLALBAP00709 details
Beta-1,4-galactosyltransferase 1B4GALT19p13P15291 details
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3PLOD37q22O60568 details
Chondroitin sulfate N-acetylgalactosaminyltransferase 1CSGALNACT18p21.3Q8TDX6 details
6-phosphofructokinase type CPFKP10p15.3-p15.2Q01813 details
6-phosphofructokinase, liver typePFKL21q22.3P17858 details
6-phosphofructokinase, muscle typePFKM12q13.3P08237 details
Pyruvate kinase isozymes M1/M2PKM15q22P14618 details
Pyruvate kinase isozymes R/LPKLR1q21P30613 details
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2B3GAT26q13Q9NPZ5 details
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1B3GAT111q25Q9P2W7 details
Polypeptide N-acetylgalactosaminyltransferase 10GALNT105q33.2Q86SR1 details
Beta-1,4-galactosyltransferase 3B4GALT31q21-q23O60512 details
Beta-1,4-galactosyltransferase 4B4GALT43q13.3O60513 details
Glycogenin-1GYG13q24-q25.1P46976 details
Histo-blood group ABO system transferaseABO9q34.2P16442 details
Chondroitin sulfate synthase 3CHSY35q23.3Q70JA7 details
Chondroitin sulfate synthase 2CHPF2q35Q8IZ52 details
Chondroitin sulfate synthase 1CHSY115q26.3Q86X52 details
Exostosin-like 3EXTL38p21O43909 details
Beta-1,4-galactosyltransferase 7B4GALT75q35.2-q35.3Q9UBV7 details
Chondroitin sulfate N-acetylgalactosaminyltransferase 2CSGALNACT210q11.21Q8N6G5 details
Exostosin-like 2EXTL21p21Q9UBQ6 details
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase AMGAT4A2q12Q9UM21 details
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase BMGAT4B5q35Q9UQ53 details
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1C1GALT17p21.3Q9NS00 details
Beta-1,4-galactosyltransferase 6B4GALT618q11Q9UBX8 details
Ribonucleoside-diphosphate reductase subunit M2 BRRM2B8q23.1Q7LG56 details
Polypeptide N-acetylgalactosaminyltransferase-like 6GALNTL64q34.1Q49A17 details
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferaseMGAT15q35P26572 details
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase CMGAT4C12q21Q9UBM8 details
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase BMGAT5B17q25.2Q3V5L5 details
Receptors
Protein NameGene NameLocusUniprot IDDetails
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunitOGTXq13O15294 details
Transcriptional Factors
Protein NameGene NameLocusUniprot IDDetails
Ribonucleoside-diphosphate reductase subunit M2RRM22p25-p24P31350 details
Nucleoside diphosphate kinase BNME217q21.3P22392 details
Hyaluronan synthase 3HAS316q22.1O00219 details
Concentrations Data
Not Available
HMDB IDHMDB0000295
DrugBank IDDB03435
Phenol Explorer Compound IDNot Available
FoodDB IDFDB031236
KNApSAcK IDC00007313
Chemspider ID5809
KEGG Compound IDC00015
BioCyc IDUDP
BiGG ID33518
Wikipedia LinkUridine_Diphosphate
METLIN IDNot Available
PubChem Compound6031
PDB IDNot Available
ChEBI ID17659
References
General ReferencesNot Available

Only showing the first 10 proteins. There are 191 proteins in total.

Enzymes

General function:
Involved in ATP binding
Specific function:
Catalyzes specific phosphoryl transfer from ATP to UMP and CMP.
Gene Name:
CMPK1
Uniprot ID:
P30085
Molecular weight:
20180.12
General function:
Involved in hydrolase activity
Specific function:
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.
Gene Name:
ENTPD1
Uniprot ID:
P49961
Molecular weight:
58706.0
General function:
Involved in calcium ion binding
Specific function:
Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP. Involved in proteoglycan synthesis.
Gene Name:
CANT1
Uniprot ID:
Q8WVQ1
Molecular weight:
44839.24
General function:
Involved in hydrolase activity
Specific function:
Has a threefold preference for the hydrolysis of ATP over ADP.
Gene Name:
ENTPD3
Uniprot ID:
O75355
Molecular weight:
59104.76
General function:
Involved in ATP binding
Specific function:
Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine.
Gene Name:
UCK1
Uniprot ID:
Q9HA47
Molecular weight:
22760.43
General function:
Involved in nucleoside diphosphate kinase activity
Specific function:
Major role in the synthesis of nucleoside triphosphates other than ATP (By similarity).
Gene Name:
NME4
Uniprot ID:
O00746
Molecular weight:
20658.45
General function:
Involved in oxidation reduction
Specific function:
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
Gene Name:
RRM1
Uniprot ID:
P23921
Molecular weight:
90069.375
General function:
Involved in nucleoside diphosphate kinase activity
Specific function:
Major role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination.
Gene Name:
NME1
Uniprot ID:
P15531
Molecular weight:
17148.635
General function:
Involved in nucleoside diphosphate kinase activity
Specific function:
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
Gene Name:
NME7
Uniprot ID:
Q9Y5B8
Molecular weight:
42491.365
General function:
Involved in oxidoreductase activity
Specific function:
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
Gene Name:
RRM2
Uniprot ID:
P31350
Molecular weight:
44877.25

Only showing the first 10 proteins. There are 191 proteins in total.