| Identification |
|---|
| HMDB Protein ID
| CDBP02441 |
| Secondary Accession Numbers
| Not Available |
| Name
| Polypeptide N-acetylgalactosaminyltransferase 9 |
| Description
| Not Available |
| Synonyms
|
- GalNAc-T9
- Polypeptide GalNAc transferase 9
- Protein-UDP acetylgalactosaminyltransferase 9
- UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9
- pp-GaNTase 9
|
| Gene Name
| GALNT9 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein binding |
| Specific Function
| Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Does not glycosylate apomucin or SDC3.
|
| GO Classification
|
| Biological Process |
| O-glycan processing |
| post-translational protein modification |
| Cellular Component |
| integral to membrane |
| Golgi membrane |
| Function |
| binding |
| protein binding |
| Molecular Function |
| polypeptide N-acetylgalactosaminyltransferase activity |
|
| Cellular Location
|
- Golgi apparatus membrane
- Single-pass type II membrane protein
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | protein glycosylation | Not Available | Not Available | | Mucin type O-Glycan biosynthesis | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| 12 |
| Locus
| 12q24.33 |
| SNPs
| GALNT9 |
| Gene Sequence
|
>1812 bp
ATGGCGGTGGCCAGGAAGATCCGAACTTTGCTGACGGTGAACATCCTGGTGTTCGTGGGC
ATCGTCCTGTTCTCCGTGTACTGCCGCCTGCAGGGCCGCTCCCAGGAGCTCGTGCGCATC
GTGAGCGGCGACCGCCGGGTGCGCAGCCGACACGCCAAGGTGGGCACGCTGGGGGACCGT
GAGGCCATCCTGCAGCGCCTGGACCACCTGGAGGAGGTGGTCTACAACCAGCTCAACGGC
CTTGCCAAGCCCATCGGCCTGGTGGAGGGGCCAGGAGGTCTGGGCCAGGGTGGCTTGGCG
GCCACCCTGCGTGATGACGGCCAGGAGGCGGAAGGCAAGTATGAGGAGTACGGCTACAAC
GCTCAGCTCAGCGACCGCATCTCCCTCGATCGGAGCATCCCCGACTACCGGCCCAGAAAG
TGCAGACAGATGAGCTACGCCCAGGACCTGCCCCAGGTCTCCGTGGTCTTCATCTTCGTC
AATGAGGCGCTGTCGGTCATCCTGCGCTCCGTGCACAGCGTGGTCAACCACACGCCCTCC
CAGCTCCTCAAGGAGGTCATCCTGGTGGACGACAACAGTGACAACGTGGAACTCAAGTTC
AATCTGGACCAGTACGTCAACAAGCGGTACCCAGGCCTCGTGAAGATTGTCCGCAACAGC
CGGCGGGAAGGACTGATCCGCGCGCGGCTGCAGGGCTGGAAGGCGGCCACCGCCCCAGTC
GTCGGCTTCTTTGATGCCCACGTCGAGTTCAACACGGGTTGGGCCGAGCCCGCACTGTCG
CGGATCCGAGAGGACCGGCGTCGCATCGTGCTGCCAGCCATCGACAACATCAAGTACAGC
ACGTTTGAGGTGCAGCAGTATGCGAACGCCGCCCATGGCTACAACTGGGGCCTCCGGTGC
ATGTACATCATCCCCCCGCAGGACTGGCTGGACCGCGGCGACGAGTCAGCACCCATCAGG
ACCCCAGCCATGATCGGCTGCTCCTTCGTAGTGGACCGCGAGTACTTCGGAGACATTGGG
CTGCTGGACCCCGGCATGGAGGTGTATGGCGGCGAGAACGTAGAACTGGGCATGAGGGTG
TGGCAGTGTGGCGGCAGCATGGAGGTGCTGCCCTGCTCCCGCGTGGCCCACATCGAGCGC
ACCAGGAAGCCCTACAACAACGACATTGACTACTACGCCAAGCGCAACGCCCTGCGCGCC
GCCGAGGTGTGGATGGATGACTTCAAGTCCCACGTGTACATGGCCTGGAACATCCCCATG
TCGAACCCAGGGGTGGACTTCGGGGACGTGTCTGAGAGGCTGGCCCTGCGTCAGAGGCTG
AAGTGTCGCAGCTTCAAGTGGTACCTGGAGAACGTGTACCCGGAGATGAGGGTCTACAAC
AACACCCTCACGTACGGAGAGGTGAGAAACAGCAAAGCCAGTGCCTACTGTCTGGACCAG
GGAGCGGAGGACGGCGACCGGGCGATCCTCTACCCCTGCCACGGGATGTCCTCCCAGCTG
GTGCGGTACAGCGCTGACGGCCTGCTGCAGCTGGGGCCTCTGGGCTCCACAGCCTTCTTG
CCTGACTCCAAGTGTCTGGTGGATGACGGCACGGGCCGCATGCCCACCCTGAAGAGGTGT
GAGGATGTGGCGCGGCCAACACAGCGGCTGTGGGACTTCACCCAGAGTGGCCCCATTGTG
AGCCGGGCCACGGGCCGCTGCCTGGAGGTGGAGATGTCCAAAGATGCCAACTTTGGGCTC
CGGCTGGTGGTACAGAGGTGCTCGGGGCAGAAGTGGATGATCAGAAACTGGATCAAACAC
GCACGGCACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 603 |
| Molecular Weight
| 68388.61 |
| Theoretical pI
| 8.35 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Polypeptide N-acetylgalactosaminyltransferase 9
MAVARKIRTLLTVNILVFVGIVLFSVYCRLQGRSQELVRIVSGDRRVRSRHAKVGTLGDR
EAILQRLDHLEEVVYNQLNGLAKPIGLVEGPGGLGQGGLAATLRDDGQEAEGKYEEYGYN
AQLSDRISLDRSIPDYRPRKCRQMSYAQDLPQVSVVFIFVNEALSVILRSVHSVVNHTPS
QLLKEVILVDDNSDNVELKFNLDQYVNKRYPGLVKIVRNSRREGLIRARLQGWKAATAPV
VGFFDAHVEFNTGWAEPALSRIREDRRRIVLPAIDNIKYSTFEVQQYANAAHGYNWGLRC
MYIIPPQDWLDRGDESAPIRTPAMIGCSFVVDREYFGDIGLLDPGMEVYGGENVELGMRV
WQCGGSMEVLPCSRVAHIERTRKPYNNDIDYYAKRNALRAAEVWMDDFKSHVYMAWNIPM
SNPGVDFGDVSERLALRQRLKCRSFKWYLENVYPEMRVYNNTLTYGEVRNSKASAYCLDQ
GAEDGDRAILYPCHGMSSQLVRYSADGLLQLGPLGSTAFLPDSKCLVDDGTGRMPTLKKC
EDVARPTQRLWDFTQSGPIVSRATGRCLEVEMSKDANFGLRLVVQRCSGQKWMIRNWIKH
ARH
|
| External Links |
|---|
| GenBank ID Protein
| 10336504 |
| UniProtKB/Swiss-Prot ID
| Q9HCQ5 |
| UniProtKB/Swiss-Prot Entry Name
| GALT9_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB040672 |
| GeneCard ID
| GALNT9 |
| GenAtlas ID
| GALNT9 |
| HGNC ID
| HGNC:4131 |
| References |
|---|
| General References
| Not Available |