Identification |
HMDB Protein ID
| CDBP05283 |
Secondary Accession Numbers
| Not Available |
Name
| EGF domain-specific O-linked N-acetylglucosamine transferase |
Description
| Not Available |
Synonyms
|
- Extracellular O-linked N-acetylglucosamine transferase
|
Gene Name
| EOGT |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Not Available |
Specific Function
| Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains (By similarity).
|
GO Classification
|
Biological Process |
protein O-linked glycosylation |
Cellular Component |
endoplasmic reticulum lumen |
Molecular Function |
protein N-acetylglucosaminyltransferase activity |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| 3 |
Locus
| 3p14.1 |
SNPs
| Not Available |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| Not Available |
Molecular Weight
| 52296.26 |
Theoretical pI
| 6.818 |
Pfam Domain Function
|
Not Available |
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>gi|39930531|ref|NP_775925.1| EGF domain-specific O-linked N-acetylglucosamine transferase precursor [Homo sapiens]
MLMLFVFGVLLHEVSLSGQNEAPPNTHSIPGEPLYNYASIRLPEEHIPFFLHNNRHIATV
CRKDSLCPYK
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| Q5NDL2 |
UniProtKB/Swiss-Prot Entry Name
| Not Available |
PDB IDs
|
Not Available |
GenBank Gene ID
| Not Available |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| HGNC:28526 |
References |
General References
| Not Available |