Identification
HMDB Protein ID CDBP00991
Secondary Accession Numbers Not Available
Name UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1
Description Not Available
Synonyms
  1. Beta-1,3-GalNAc-T1
  2. Beta-1,3-GalTase 3
  3. Beta-1,3-galactosyltransferase 3
  4. Beta-3-Gx-T3
  5. Beta3Gal-T3
  6. Beta3GalT3
  7. Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase
  8. Globoside synthase
  9. UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase
  10. b3Gal-T3
Gene Name B3GALNT1
Protein Type Enzyme
Biological Properties
General Function Involved in galactosyltransferase activity
Specific Function Transfers N-acetylgalactosamine onto globotriaosylceramide.
GO Classification
Biological Process
oligosaccharide biosynthetic process
protein glycosylation
Cellular Component
integral to membrane
Golgi membrane
Component
membrane
cell part
Function
galactosyltransferase activity
catalytic activity
transferase activity
transferase activity, transferring hexosyl groups
transferase activity, transferring glycosyl groups
Molecular Function
UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity
galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity
Process
metabolic process
macromolecule metabolic process
macromolecule modification
protein modification process
protein amino acid glycosylation
Cellular Location
  1. Golgi apparatus membrane
  2. Single-pass type II membrane protein
Pathways
Gene Properties
Chromosome Location 3
Locus 3q25
SNPs B3GALNT1
Gene Sequence
>996 bp
ATGGCCTCGGCTCTCTGGACTGTCCTTCCGAGTAGGATGTCACTGAGATCCCTCAAATGG
AGCCTCCTGCTGCTGTCACTCCTGAGTTTCTTTGTGATGTGGTACCTCAGCCTTCCCCAC
TACAATGTGATAGAACGCGTGAACTGGATGTACTTCTATGAGTATGAGCCGATTTACAGA
CAAGACTTTCACTTCACACTTCGAGAGCATTCAAACTGCTCTCATCAAAATCCATTTCTG
GTCATTCTGGTGACCTCCCACCCTTCAGATGTGAAAGCCAGGCAGGCCATTAGAGTTACT
TGGGGTGAAAAAAAGTCTTGGTGGGGATATGAGGTTCTTACATTTTTCTTATTAGGCCAA
GAGGCTGAAAAGGAAGACAAAATGTTGGCATTGTCCTTAGAGGATGAACACCTTCTTTAT
GGTGACATAATCCGACAAGATTTTTTAGACACATATAATAACCTGACCTTGAAAACCATT
ATGGCATTCAGGTGGGTAACTGAGTTTTGCCCCAATGCCAAGTACGTAATGAAGACAGAC
ACTGATGTTTTCATCAATACTGGCAATTTAGTGAAGTATCTTTTAAACCTAAACCACTCA
GAGAAGTTTTTCACAGGTTATCCTCTAATTGATAATTATTCCTATAGAGGATTTTACCAA
AAAACCCATATTTCTTACCAGGAGTATCCTTTCAAGGTGTTCCCTCCATACTGCAGTGGG
TTGGGTTATATAATGTCCAGAGATTTGGTGCCAAGGATCTATGAAATGATGGGTCACGTA
AAACCCATCAAGTTTGAAGATGTTTATGTCGGGATCTGTTTGAATTTATTAAAAGTGAAC
ATTCATATTCCAGAAGACACAAATCTTTTCTTTCTATATAGAATCCATTTGGATGTCTGT
CAACTGAGACGTGTGATTGCAGCCCATGGCTTTTCTTCCAAGGAGATCATCACTTTTTGG
CAGGTCATGCTAAGGAACACCACATGCCATTATTAA
Protein Properties
Number of Residues 331
Molecular Weight 39511.55
Theoretical pI 7.799
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1
MASALWTVLPSRMSLRSLKWSLLLLSLLSFFVMWYLSLPHYNVIERVNWMYFYEYEPIYR
QDFHFTLREHSNCSHQNPFLVILVTSHPSDVKARQAIRVTWGEKKSWWGYEVLTFFLLGQ
EAEKEDKMLALSLEDEHLLYGDIIRQDFLDTYNNLTLKTIMAFRWVTEFCPNAKYVMKTD
TDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGFYQKTHISYQEYPFKVFPPYCSG
LGYIMSRDLVPRIYEMMGHVKPIKFEDVYVGICLNLLKVNIHIPEDTNLFFLYRIHLDVC
QLRRVIAAHGFSSKEIITFWQVMLRNTTCHY
GenBank ID Protein 3256005
UniProtKB/Swiss-Prot ID O75752
UniProtKB/Swiss-Prot Entry Name B3GL1_HUMAN
PDB IDs Not Available
GenBank Gene ID Y15062
GeneCard ID B3GALNT1
GenAtlas ID B3GALNT1
HGNC ID HGNC:918
References
General References Not Available