Cannabis Compound Database: Showing Protein UMP-CMP kinase (CDBP00003)

Identification Biological properties Gene properties Protein properties External links References XML Show 9 compounds

Identification

HMDB Protein ID

CDBP00003

Secondary Accession Numbers

Not Available

Name

UMP-CMP kinase

Description

Not Available

Synonyms

Cytidine monophosphate kinase
Cytidylate kinase
Deoxycytidylate kinase
UMP/CMP kinase
UMP/CMPK
Uridine monophosphate kinase
Uridine monophosphate/cytidine monophosphate kinase

Gene Name

CMPK1

Protein Type

Enzyme

Biological Properties

General Function

Involved in ATP binding

Specific Function

Catalyzes specific phosphoryl transfer from ATP to UMP and CMP.

GO Classification

Biological Process
nucleobase-containing small molecule interconversion
Cellular Component
cytosol
nucleus
Function
nucleotide kinase activity
phosphotransferase activity, phosphate group as acceptor
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleobase, nucleoside, nucleotide kinase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
binding
catalytic activity
Molecular Function
ATP binding
cytidylate kinase activity
phosphotransferase activity, phosphate group as acceptor
uridine kinase activity
Process
nitrogen compound metabolic process
cellular nitrogen compound metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
metabolic process

Cellular Location

Nucleus
Cytoplasm

Pathways

Name	SMPDB/Pathwhiz	KEGG
Lactose Synthesis		Not Available
Congenital disorder of glycosylation CDG-IId		Not Available
GLUT-1 deficiency syndrome		Not Available
Gemcitabine Action Pathway		Not Available
Gemcitabine Metabolism Pathway		Not Available

Gene Properties

Chromosome Location

Locus

1p32

SNPs

CMPK1

Gene Sequence

>591 bp
ATGAAGCCGCTGGTCGTGTTCGTCCTCGGCGGCCCCGGCGCCGGCAAGGGGACCCAGTGC
GCCCGCATCGTCGAGAAATATGGCTACACACACCTTTCTGCAGGAGAGCTGCTTCGTGAT
GAAAGGAAGAACCCAGATTCACAGTATGGTGAACTTATTGAAAAGTACATTAAAGAAGGA
AAGATTGTACCAGTTGAGATAACCATCAGTTTATTAAAGAGGGAAATGGATCAGACAATG
GCTGCCAATGCTCAGAAGAATAAATTCTTGATTGATGGGTTTCCAAGAAATCAAGACAAC
CTTCAAGGATGGAACAAGACCATGGATGGGAAGGCAGATGTATCTTTCGTTCTCTTTTTT
GACTGTAATAATGAGATTTGTATTGAACGATGTCTTGAGAGGGGAAAGAGTAGTGGTAGG
AGTGATGACAACAGAGAGAGCTTGGAAAAGAGAATTCAGACCTACCTTCAGTCAACAAAG
CCAATTATTGACTTATATGAAGAAATGGGGAAAGTCAAGAAAATAGATGCTTCTAAATCT
GTTGATGAAGTTTTTGATGAAGTTGTGCAGATTTTTGACAAGGAAGGCTAA

Protein Properties

Number of Residues

196

Molecular Weight

20180.12

Theoretical pI

7.631

Pfam Domain Function

ADK (PF00406 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>UMP-CMP kinase
MKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEG
KIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFF
DCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKS
VDEVFDEVVQIFDKEG

External Links

GenBank ID Protein

33150592

UniProtKB/Swiss-Prot ID

P30085

UniProtKB/Swiss-Prot Entry Name

KCY_HUMAN

PDB IDs