Cannabis Compound Database: Showing Protein Beta-1,4-galactosyltransferase 4 (CDBP00970)

Identification Biological properties Gene properties Protein properties External links References XML Show 2 compounds

Identification

HMDB Protein ID

CDBP00970

Secondary Accession Numbers

Not Available

Name

Beta-1,4-galactosyltransferase 4

Description

Not Available

Synonyms

Beta-1,4-GalTase 4
Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase
Beta4Gal-T4
N-acetyllactosamine synthase
Nal synthase
UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4
UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4
b4Gal-T4

Gene Name

B4GALT4

Protein Type

Enzyme

Biological Properties

General Function

Involved in transferase activity, transferring glycosyl groups

Specific Function

Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

GO Classification

Biological Process
keratan sulfate biosynthetic process
post-translational protein modification
protein N-linked glycosylation via asparagine
membrane lipid metabolic process
Cellular Component
Golgi cisterna membrane
integral to membrane
Golgi membrane
Function
catalytic activity
transferase activity
transferase activity, transferring glycosyl groups
Molecular Function
N-acetyllactosamine synthase activity
metal ion binding
galactosyltransferase activity
Process
primary metabolic process
carbohydrate metabolic process
metabolic process

Cellular Location

Single-pass type II membrane protein
Golgi apparatus
Golgi stack membrane

Pathways

Name	SMPDB/Pathwhiz	KEGG
protein glycosylation	Not Available	Not Available
Glycosaminoglycan biosynthesis - keratan sulfate	Not Available
Glycosphingolipid biosynthesis - lacto and neolacto series	Not Available

Gene Properties

Chromosome Location

Locus

3q13.3

SNPs

B4GALT4

Gene Sequence

>1035 bp
ATGGGCTTCAACCTGACTTTCCACCTTTCCTACAAATTCCGATTACTGTTGCTGTTGACT
TTGTGCCTGACAGTGGTTGGGTGGGCCACCAGTAACTACTTCGTGGGTGCCATTCAAGAG
ATTCCTAAAGCAAAGGAGTTCATGGCTAATTTCCATAAGACCCTCATTTTGGGGAAGGGA
AAAACTCTGACTAATGAAGCATCCACGAAGAAGGTAGAACTTGACAACTGCCCTTCTGTG
TCTCCTTACCTCAGAGGCCAGAGCAAGCTCATTTTCAAACCAGATCTCACTTTGGAAGAG
GTACAGGCAGAAAATCCCAAAGTGTCCAGAGGCCGGTATCGCCCTCAGGAATGTAAAGCT
TTACAGAGGGTCGCCATCCTCGTTCCCCACCGGAACAGAGAGAAACACCTGATGTACCTG
CTGGAACATCTGCATCCCTTCCTGCAGAGGCAGCAGCTGGATTATGGCATCTACGTCATC
CACCAGGCTGAAGGTAAAAAGTTTAATCGAGCCAAACTCTTGAATGTGGGCTATCTAGAA
GCCCTCAAGGAAGAAAATTGGGACTGCTTTATATTCCACGATGTGGACCTGGTACCCGAG
AATGACTTTAACCTTTACAAGTGTGAGGAGCATCCCAAGCATCTGGTGGTTGGCAGGAAC
AGCACTGGGTACAGGTTACGTTACAGTGGATATTTTGGGGGTGTTACTGCCCTAAGCAGA
GAGCAGTTTTTCAAGGTGAATGGATTCTCTAACAACTACTGGGGATGGGGAGGCGAAGAC
GATGACCTCAGACTCAGGGTTGAGCTCCAAAGAATGAAAATTTCCCGGCCCCTGCCTGAA
GTGGGTAAATATACAATGGTCTTCCACACTAGAGACAAAGGCAATGAGGTGAACGCAGAA
CGGATGAAGCTCTTACACCAAGTGTCACGAGTCTGGAGAACAGATGGGTTGAGTAGTTGT
TCTTATAAATTAGTATCTGTGGAACACAATCCTTTATATATCAACATCACAGTGGATTTC
TGGTTTGGTGCATGA

Protein Properties

Number of Residues

344

Molecular Weight

40040.865

Theoretical pI

9.074

Pfam Domain Function

Galactosyl_T_2 (PF02709 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Beta-1,4-galactosyltransferase 4
MGFNLTFHLSYKFRLLLLLTLCLTVVGWATSNYFVGAIQEIPKAKEFMANFHKTLILGKG
KTLTNEASTKKVELDNCPSVSPYLRGQSKLIFKPDLTLEEVQAENPKVSRGRYRPQECKA
LQRVAILVPHRNREKHLMYLLEHLHPFLQRQQLDYGIYVIHQAEGKKFNRAKLLNVGYLE
ALKEENWDCFIFHDVDLVPENDFNLYKCEEHPKHLVVGRNSTGYRLRYSGYFGGVTALSR
EQFFKVNGFSNNYWGWGGEDDDLRLRVELQRMKISRPLPEVGKYTMVFHTRDKGNEVNAE
RMKLLHQVSRVWRTDGLSSCSYKLVSVEHNPLYINITVDFWFGA

External Links

GenBank ID Protein

Not Available

UniProtKB/Swiss-Prot ID

O60513

UniProtKB/Swiss-Prot Entry Name

B4GT4_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AF038662

GeneCard ID