Identification |
HMDB Protein ID
| CDBP00542 |
Secondary Accession Numbers
| Not Available |
Name
| GTP:AMP phosphotransferase, mitochondrial |
Description
| Not Available |
Synonyms
|
- AK 3
- Adenylate kinase 3
- Adenylate kinase 3 alpha-like 1
|
Gene Name
| AK3 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in ATP binding |
Specific Function
| Not Available |
GO Classification
|
Biological Process |
GTP metabolic process |
ITP metabolic process |
UTP metabolic process |
blood coagulation |
AMP metabolic process |
AMP phosphorylation |
Cellular Component |
mitochondrial matrix |
Function |
adenyl ribonucleotide binding |
atp binding |
binding |
catalytic activity |
nucleotide kinase activity |
phosphotransferase activity, phosphate group as acceptor |
transferase activity |
adenylate kinase activity |
transferase activity, transferring phosphorus-containing groups |
kinase activity |
nucleobase, nucleoside, nucleotide kinase activity |
nucleoside binding |
purine nucleoside binding |
adenyl nucleotide binding |
Molecular Function |
ATP binding |
GTP binding |
adenylate kinase activity |
nucleoside triphosphate adenylate kinase activity |
nucleotide kinase activity |
Process |
metabolic process |
nitrogen compound metabolic process |
cellular nitrogen compound metabolic process |
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
|
Cellular Location
|
- Mitochondrion matrix
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Pyrimidine Metabolism | | | Beta Ureidopropionase Deficiency | | Not Available | UMP Synthase Deficiency (Orotic Aciduria) | | Not Available | Dihydropyrimidinase Deficiency | | Not Available | MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy) | | Not Available |
|
Gene Properties |
Chromosome Location
| 9 |
Locus
| 9p24.1 |
SNPs
| AK3 |
Gene Sequence
|
>684 bp
ATGGGGGCGTCGGGGCGGCTGCTGCGAGCGGTGATCATGGGGGCCCCGGGCTCGGGCAAG
GGCACCGTGTCGTCCCGCATCACTACACACTTCGAGCTGAAGCACCTCTCCCGCGGGGAC
CTGCTCCGGGACAACATGCTGCGGGGCACAGAAATTGGCGTGTTAGCCCAGGCTTTCATT
GACCAAGGGAAACTCATCCCAGATTATGTCACGACTCGGCTGGCCCTTCATGAGCTGAAA
AACCTCACCCAGTATAGCTGGCTGTTGGATGGTTTTCCAAGGACACTTCCACAGGCAGAA
GCCCTAGATAGAGCTTATCAGATCGACACAGTGATTAACCTGAATGTGCCCTTTGAGGTC
ATTAAACAACGCCTTACTGCTCGCTGGATTCATCCCGCCAGTGGCCGAGTCTATAACATT
GAATTCAACCCTCCCAAAACTGTGGGCATTGATGACCTGACTGGGGAGCCTCTCATTCAG
CGTGAGGATGATAAACCAGAGACGGTTATCAAGAGACTAAAGGCTTATGAAGACCAAACA
AAGCCAGTCCTGGAATATTACCAGAAAAAAGGGGTGTTGGAAACATTCTCCGGAACAGAA
ACCAACAAGATTTGGCCCTATGTATATGCTTTCCTACAAACTAAAGTTCCACAAAGAAGC
CAGAAAGCTTCAGTTACTCCATGA
|
Protein Properties |
Number of Residues
| 227 |
Molecular Weight
| 21013.93 |
Theoretical pI
| 9.522 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>GTP:AMP phosphotransferase, mitochondrial
MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFI
DQGKLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEV
IKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQT
KPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP
|
External Links |
GenBank ID Protein
| 6518533 |
UniProtKB/Swiss-Prot ID
| Q9UIJ7 |
UniProtKB/Swiss-Prot Entry Name
| KAD3_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| AB021870 |
GeneCard ID
| AK3 |
GenAtlas ID
| AK3 |
HGNC ID
| HGNC:17376 |
References |
General References
| Not Available |