| Identification |
|---|
| HMDB Protein ID
| CDBP02926 |
| Secondary Accession Numbers
| Not Available |
| Name
| Polypeptide N-acetylgalactosaminyltransferase-like 6 |
| Description
| Not Available |
| Synonyms
|
- GalNAc-T17
- Polypeptide GalNAc transferase 17
- Protein-UDP acetylgalactosaminyltransferase 17
- Putative polypeptide N-acetylgalactosaminyltransferase 17
- UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 17
- pp-GaNTase 17
|
| Gene Name
| GALNTL6 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in metal ion binding |
| Specific Function
| Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor (By similarity).
|
| GO Classification
|
| Biological Process |
| protein glycosylation |
| Cellular Component |
| Golgi membrane |
| integral to membrane |
| Molecular Function |
| metal ion binding |
| polypeptide N-acetylgalactosaminyltransferase activity |
|
| Cellular Location
|
- Golgi apparatus membrane
- Single-pass type II membrane protein
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | protein glycosylation | Not Available | Not Available | | Mucin type O-Glycan biosynthesis | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| 4 |
| Locus
| 4q34.1 |
| SNPs
| GALNTL6 |
| Gene Sequence
|
>1806 bp
ATGAAGAGGAAACAGAAGAGATTTCTGCAGATGACTTTGTTGTTCACGGTGGCTTTAATT
TTCCTGCCTAACGTTGGTCTCTGGTCTCTGTACAAGGATAAGCACCTGGTGAAGTCAGCG
GAGCCCGGGGAGCAGCAGACATTTCCACTGGGCCTGGGAGATGGGCAATTCTATTCATGG
ACAGATGGTTTGAGAAGAAAGGACTGGCATGACTATGAAAGCATTCAGAAAGAGGCTATG
CGCTCAGGGAAAGGTGAACATGGGAAACCTTACCCCCTTACTGAAGAGGACCATGATGAC
TCAGCTTACAGGGAAAATGGTTTTAATATTTTCGTCAGCAACAATATTGCTCTAGAGAGG
TCTCTGCCAGATATTCGTCATGCTAACTGTAAGCATAAGATGTATCTGGAAAGGCTGCCA
AACACCAGCATCATTATCCCATTTCATAATGAAGGTTGGACTTCACTCCTGCGGACCATA
CACAGTATAATTAACCGAACCCCAGGGAGTCTGATAGCAGAAATCATTCTAGTAGATGAC
TTCAGTGAGAGAGAACACCTGAAGGATAAATTGGAAGAATACATGGCCCGATTTTCCAAA
GTGAGGATTGTTCGCACCAAGAAAAGAGAAGGACTCATCCGGACCCGTCTCCTGGGGGCA
TCTATGGCCAGAGGAGAAGTCCTGACATTCCTGGACTCCCACTGCGAGGTCAATGTGAAC
TGGCTGCCCCCACTCCTCAACCAAATTGCACTAAACCACAAAACCATCGTGTGTCCCATG
ATCGATGTCATTGACCACAATCACTTCGGGTATGAGGCACAAGCTGGGGATGCCATGCGA
GGAGCCTTCGACTGGGAAATGTACTACAAAAGAATCCCCATCCCTCCAGAGCTCCAGAGG
GCAGATCCCAGCGACCCTTTTGAGTCTCCTGTTATGGCTGGAGGTCTCTTTGCTGTGGAT
CGGAAATGGTTTTGGGAATTGGGTGGCTATGATCCAGGTTTAGAAATCTGGGGAGGAGAA
CAGTATGAAATCTCTTTTAAGGTTTGGATGTGTGGAGGAGAAATGTTTGATGTTCCATGT
TCTAGAGTTGGTCATATCTACAGGAAGTACGTTCCATACAAAGTTCCATCTGGGACAAGC
CTGGCAAGAAACCTGAAGCGGGTAGCTGAGACCTGGATGGATGAATTTGCCGAGTACATT
TACCAGCGGCGGCCGGAGTACAGGCATCTCTCCACGGGGGACATCTCTGCCCAGAAGGAG
CTGCGCAAGCAGCTCAAGTGCAAGGACTTCAAATGGTTCATGGCTGCTGTGGCCTGGGAC
GTGCCTAAATACTACCCTCCAGTGGAGCCCCCGCCTGCTGCCTGGGGGGAGATCCGAAAT
GTGGCAGCAAATCTCTGTGTGGACAGCAAGCATGGAGCCACCGGAACAGAGCTGAGGCTG
GACATCTGTGTCAAGGATGGTTCTGAAAGAACATGGTCTCATGAACAGCTTTTTACCTTT
GGATGGAGAGAAGATATTCGACCCGGTGAGCCACTGCATACCCGGAAATTCTGCTTTGAT
GCGATCTCACACAACAGCCCCGTTACACTCTATGACTGTCATGGCATGAAGGGGAACCAG
CTCTGGGGATACCGGAAGGACAGAACATTATTCCATCCTGTGAGCAACAGCTGCATGGAT
TGCAACCCCGCAGAGAAGAAGATTTTCATGGCCAGATGTGACCCTCTCTCTGAGACTCAG
CAGTGGATTTTTGAACACATTAATATGACTGTTTTAGAAAAATTTAACCACCATGCCAAC
TCCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 601 |
| Molecular Weight
| 69787.21 |
| Theoretical pI
| 7.455 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Polypeptide N-acetylgalactosaminyltransferase-like 6
MKRKQKRFLQMTLLFTVALIFLPNVGLWSLYKDKHLVKSAEPGEQQTFPLGLGDGQFYSW
TDGLRRKDWHDYESIQKEAMRSGKGEHGKPYPLTEEDHDDSAYRENGFNIFVSNNIALER
SLPDIRHANCKHKMYLERLPNTSIIIPFHNEGWTSLLRTIHSIINRTPGSLIAEIILVDD
FSEREHLKDKLEEYMARFSKVRIVRTKKREGLIRTRLLGASMARGEVLTFLDSHCEVNVN
WLPPLLNQIALNHKTIVCPMIDVIDHNHFGYEAQAGDAMRGAFDWEMYYKRIPIPPELQR
ADPSDPFESPVMAGGLFAVDRKWFWELGGYDPGLEIWGGEQYEISFKVWMCGGEMFDVPC
SRVGHIYRKYVPYKVPSGTSLARNLKRVAETWMDEFAEYIYQRRPEYRHLSTGDISAQKE
LRKQLKCKDFKWFMAAVAWDVPKYYPPVEPPPAAWGEIRNVAANLCVDSKHGATGTELRL
DICVKDGSERTWSHEQLFTFGWREDIRPGEPLHTRKFCFDAISHNSPVTLYDCHGMKGNQ
LWGYRKDRTLFHPVSNSCMDCNPAEKKIFMARCDPLSETQQWIFEHINMTVLEKFNHHAN
S
|
| External Links |
|---|
| GenBank ID Protein
| 194018457 |
| UniProtKB/Swiss-Prot ID
| Q49A17 |
| UniProtKB/Swiss-Prot Entry Name
| GLTL6_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_001034845.2 |
| GeneCard ID
| GALNTL6 |
| GenAtlas ID
| GALNTL6 |
| HGNC ID
| HGNC:33844 |
| References |
|---|
| General References
| Not Available |