Cannabis Compound Database: Showing Protein Phosphatidylinositol N-acetylglucosaminyltransferase subunit C (CDBP00887)

Identification Biological properties Gene properties Protein properties External links References XML Show 4 compounds

Identification

HMDB Protein ID

CDBP00887

Secondary Accession Numbers

Not Available

Name

Phosphatidylinositol N-acetylglucosaminyltransferase subunit C

Description

Not Available

Synonyms

PIG-C
Phosphatidylinositol-glycan biosynthesis class C protein

Gene Name

PIGC

Protein Type

Enzyme

Biological Properties

General Function

Involved in phosphatidylinositol N-acetylglucosaminyltransferase activity

Specific Function

Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

GO Classification

Biological Process
C-terminal protein lipidation
preassembly of GPI anchor in ER membrane
Cellular Component
endoplasmic reticulum membrane
glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex
integral to membrane
Component
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
catalytic activity
transferase activity
acetylglucosaminyltransferase activity
phosphatidylinositol n-acetylglucosaminyltransferase activity
udp-glycosyltransferase activity
transferase activity, transferring glycosyl groups
Molecular Function
catalytic activity
phosphatidylinositol N-acetylglucosaminyltransferase activity
Process
metabolic process
macromolecule metabolic process
protein amino acid lipidation
gpi anchor biosynthetic process
macromolecule modification
protein modification process

Cellular Location

Multi-pass membrane protein (Potential)
Endoplasmic reticulum membrane

Pathways

Name	SMPDB/Pathwhiz	KEGG
glycosylphosphatidylinositol-anchor biosynthesis	Not Available	Not Available
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis	Not Available

Gene Properties

Chromosome Location

Locus

1q23-q25

SNPs

PIGC

Gene Sequence

>894 bp
ATGTATGCTCAACCTGTGACTAACACCAAGGAGGTCAAGTGGCAGAAGGTCTTGTATGAG
CGACAGCCCTTTCCTGATAACTATGTGGACCGGCGATTCCTGGAAGAGCTCCGGAAAAAC
ATCCATGCTCGGAAATACCAATATTGGGCTGTGGTATTTGAGTCCAGTGTGGTGATCCAG
CAGCTGTGCAGTGTTTGTGTTTTTGTGGTTATCTGGTGGTATATGGATGAGGGTCTTCTG
GCCCCCCATTGGCTTTTAGGGACTGGCCTGGCTTCTTCACTGATTGGGTATGTTTTGTTT
GATCTCATTGATGGAGGTGAAGGGCGGAAGAAGAGTGGGCAGACCCGGTGGGCTGACCTG
AAGAGTGCCCTAGTCTTCATTACTTTCACTTATGGGTTTTCACCAGTGCTGAAGACCCTT
ACAGAGTCTGTCAGCACTGACACCATCTATGCCATGTCAGTCTTCATGCTGTTAGGCCAT
CTCATCTTTTTTGACTATGGTGCCAATGCTGCCATTGTATCCAGCACACTATCCTTGAAC
ATGGCCATCTTTGCTTCTGTATGCTTGGCATCACGTCTTCCCCGGTCCCTGCATGCCTTC
ATCATGGTGACATTTGCCATTCAGATTTTTGCCCTGTGGCCCATGTTGCAGAAGAAACTA
AAGGCATGTACTCCCCGGAGCTATGTGGGGGTCACACTGCTTTTTGCATTTTCAGCCGTG
GGAGGCCTACTGTCCATTAGTGCTGTGGGAGCCGTACTCTTTGCCCTTCTGCTGATGTCT
ATCTCATGTCTGTGTTCATTCTACCTCATTCGCTTGCAGCTTTTTAAAGAAAACATTCAT
GGGCCTTGGGATGAAGCTGAAATCAAGGAAGACTTGTCCAGGTTCCTCAGTTAA

Protein Properties

Number of Residues

297

Molecular Weight

33582.18

Theoretical pI

8.41

Pfam Domain Function

GPI2 (PF06432 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Phosphatidylinositol N-acetylglucosaminyltransferase subunit C
MYAQPVTNTKEVKWQKVLYERQPFPDNYVDRRFLEELRKNIHARKYQYWAVVFESSVVIQ
QLCSVCVFVVIWWYMDEGLLAPHWLLGTGLASSLIGYVLFDLIDGGEGRKKSGQTRWADL
KSALVFITFTYGFSPVLKTLTESVSTDTIYAMSVFMLLGHLIFFDYGANAAIVSSTLSLN
MAIFASVCLASRLPRSLHAFIMVTFAIQIFALWPMLQKKLKACTPRSYVGVTLLFAFSAV
GGLLSISAVGAVLFALLLMSISCLCPFYLIRLQLFKENIHGPWDEAEIKEDLSRFLS

External Links

GenBank ID Protein

2547042

UniProtKB/Swiss-Prot ID

Q92535

UniProtKB/Swiss-Prot Entry Name

PIGC_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AB000360

GeneCard ID