Record Information
Version1.0
Created at2020-04-17 18:53:25 UTC
Updated at2020-12-07 19:11:21 UTC
CannabisDB IDCDB004947
Secondary Accession NumbersNot Available
Cannabis Compound Identification
Common NameHydrogen peroxide
DescriptionHydrogen peroxide, also known as oxydol or dihydrogen dioxide, belongs to the class of inorganic compounds known as homogeneous other non-metal compounds. These are inorganic non-metallic compounds in which the largest atom belongs to the class of 'other non-metals'. Hydrogen peroxide is an extremely weak basic (essentially neutral) compound (based on its pKa). Hydrogen peroxide exists in all living species, ranging from bacteria to humans. In humans, hydrogen peroxide is involved in disulfiram action pathway. Outside of the human body, Hydrogen peroxide has been detected, but not quantified in, several different foods, such as tree ferns, napa cabbages, lingonberries, chives, and sesames. This could make hydrogen peroxide a potential biomarker for the consumption of these foods. An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond. Hydrogen peroxide is expected to be in Cannabis as all living plants are known to produce and metabolize it.
Structure
Thumb
Synonyms
ValueSource
[OH(OH)]ChEBI
Dihydrogen dioxideChEBI
H2O2ChEBI
HOOHChEBI
OxydolChEBI
PerhydrolChEBI
OxyfullKegg
Adeka super elHMDB
AlboneHMDB
Albone 35HMDB
Albone DSHMDB
Anti-keim 50HMDB
AsepticperHMDB
BaquashockHMDB
CIXHMDB
Clarigel goldHMDB
Crestal whitestripsHMDB
CrystacideHMDB
DentaseptHMDB
Deslime LPHMDB
HioxylHMDB
HipoxHMDB
HybriteHMDB
Hydrogen dioxideHMDB
InhibineHMDB
Lase peroxideHMDB
Lensan aHMDB
Magic bleachingHMDB
MetrokurHMDB
MiraseptHMDB
Nite white excel 2HMDB
Odosat DHMDB
Opalescence xtraHMDB
OxigenalHMDB
OxyseptHMDB
Oxysept IHMDB
PegasylHMDB
PeroneHMDB
PeroxaanHMDB
PeroxcleanHMDB
Quasar briteHMDB
Select bleachHMDB
SuperoxolHMDB
T-StuffHMDB
Whiteness HPHMDB
WhitespeedHMDB
Xtra whiteHMDB
Hydrogen peroxide (H2O2)HMDB
HydroperoxideHMDB
Peroxide, hydrogenHMDB
Chemical FormulaH2O2
Average Molecular Weight34.01
Monoisotopic Molecular Weight34.0055
IUPAC Nameperoxol
Traditional Namehydrogen peroxide
CAS Registry Number7722-84-1
SMILES
OO
InChI Identifier
InChI=1S/H2O2/c1-2/h1-2H
InChI KeyMHAJPDPJQMAIIY-UHFFFAOYSA-N
Chemical Taxonomy
Description Belongs to the class of inorganic compounds known as homogeneous other non-metal compounds. These are inorganic non-metallic compounds in which the largest atom belongs to the class of 'other non-metals'.
KingdomInorganic compounds
Super ClassHomogeneous non-metal compounds
ClassHomogeneous other non-metal compounds
Sub ClassNot Available
Direct ParentHomogeneous other non-metal compounds
Alternative ParentsNot Available
Substituents
  • Homogeneous other non metal
Molecular FrameworkNot Available
External Descriptors
Ontology
Physiological effect

Health effect:

Disposition

Route of exposure:

Biological location:

Source:

Role

Industrial application:

Physical Properties
StateLiquid
Experimental Properties
PropertyValueReference
Melting Point-0.43 °CNot Available
Boiling Point150.2 °CWikipedia
Water Solubility1000 mg/mL at 25 °CNot Available
logP-0.43Wikipedia
Predicted Properties
PropertyValueSource
logP-0.45ChemAxon
pKa (Strongest Acidic)11.52ChemAxon
pKa (Strongest Basic)-4.2ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area40.46 ŲChemAxon
Rotatable Bond Count0ChemAxon
Refractivity5.13 m³·mol⁻¹ChemAxon
Polarizability2.29 ųChemAxon
Number of Rings0ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Spectra
EI-MS/GC-MS
TypeDescriptionSplash KeyView
Predicted GC-MSHydrogen peroxide, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positivesplash10-001i-9000000000-4749d46780bc552fb9afSpectrum
MS/MS
TypeDescriptionSplash KeyView
Predicted MS/MSPredicted LC-MS/MS Spectrum - 10V, Positivesplash10-000i-9000000000-50a90bb1548c24e83fbeSpectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 20V, Positivesplash10-000i-9000000000-50a90bb1548c24e83fbeSpectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 40V, Positivesplash10-000i-9000000000-50a90bb1548c24e83fbeSpectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 10V, Negativesplash10-001i-9000000000-a9a93dd42f2cfa0b34c4Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 20V, Negativesplash10-001i-9000000000-a9a93dd42f2cfa0b34c4Spectrum
Predicted MS/MSPredicted LC-MS/MS Spectrum - 40V, Negativesplash10-001i-9000000000-a9a93dd42f2cfa0b34c4Spectrum
NMRNot Available
Pathways
Pathways
Protein Targets
Enzymes
Protein NameGene NameLocusUniprot IDDetails
Peroxisomal sarcosine oxidasePIPOX17q11.2Q9P0Z9 details
Peroxisomal N(1)-acetyl-spermine/spermidine oxidasePAOX10q26.3Q6QHF9 details
Aldehyde oxidaseAOX12q33Q06278 details
Peroxisomal acyl-coenzyme A oxidase 1ACOX117q25.1Q15067 details
D-aspartate oxidaseDDO6q21Q99489 details
Amine oxidase [flavin-containing] BMAOBXp11.23P27338 details
Amine oxidase [flavin-containing] AMAOAXp11.3P21397 details
Xanthine dehydrogenase/oxidaseXDH2p23.1P47989 details
Dihydroorotate dehydrogenase (quinone), mitochondrialDHODH16q22Q02127 details
Peroxisomal acyl-coenzyme A oxidase 3ACOX34p15.3O15254 details
D-amino-acid oxidaseDAO12q24P14920 details
Thyroid peroxidaseTPO2p25P07202 details
LactoperoxidaseLPO17q23.1P22079 details
Peroxiredoxin-6PRDX61q25.1P30041 details
MyeloperoxidaseMPO17q23.1P05164 details
Eosinophil peroxidaseEPX17q23.1P11678 details
Amiloride-sensitive amine oxidase [copper-containing]ABP17q36.1P19801 details
Membrane primary amine oxidaseAOC317q21Q16853 details
Retina-specific copper amine oxidaseAOC217q21O75106 details
Pyridoxine-5'-phosphate oxidasePNPO17q21.32Q9NVS9 details
Protein-lysine 6-oxidaseLOX5q23.2P28300 details
Hydroxyacid oxidase 1HAO120p12Q9UJM8 details
Hydroxyacid oxidase 2HAO21p13.3-p13.1Q9NYQ3 details
Glutathione peroxidase 7GPX71p32Q96SL4 details
Epididymal secretory glutathione peroxidaseGPX56p22.1O75715 details
Glutathione peroxidase 6GPX66p22.1P59796 details
Glutathione peroxidase 1GPX13p21.3P07203 details
Phospholipid hydroperoxide glutathione peroxidase, mitochondrialGPX419p13.3P36969 details
Glutathione peroxidase 3GPX35q23P22352 details
Glutathione peroxidase 2GPX214q24.1P18283 details
Protoporphyrinogen oxidasePPOX1q22P50336 details
Sulfite oxidase, mitochondrialSUOX12q13.2P51687 details
CatalaseCAT11p13P04040 details
Superoxide dismutase [Mn], mitochondrialSOD26q25.3P04179 details
Superoxide dismutase [Cu-Zn]SOD121q22.11P00441 details
Peroxiredoxin-5, mitochondrialPRDX511q13P30044 details
Spermine oxidaseSMOX20p13Q9NWM0 details
Dual oxidase 2DUOX215q15.3Q9NRD8 details
Extracellular superoxide dismutase [Cu-Zn]SOD34p15.2P08294 details
Dual oxidase 1DUOX115q15.3Q9NRD9 details
Lysyl oxidase homolog 2LOXL28p21.3Q9Y4K0 details
FAD-linked sulfhydryl oxidase ALRGFER16p13.3-p13.12P55789 details
NADPH oxidase 4NOX411q14.2-q21Q9NPH5 details
L-amino-acid oxidaseIL4I119q13.3-q13.4Q96RQ9 details
Prenylcysteine oxidase 1PCYOX12p13.3Q9UHG3 details
Sulfhydryl oxidase 1QSOX11q24O00391 details
Sulfhydryl oxidase 2QSOX29q34.3Q6ZRP7 details
NADPH oxidase activator 1NOXA19q34.3Q86UR1 details
NADPH oxidase organizer 1NOXO116p13.3Q8NFA2 details
Probable glutathione peroxidase 8GPX85q11.2Q8TED1 details
TransportersNot Available
Metal Bindings
Protein NameGene NameLocusUniprot IDDetails
Aldehyde oxidaseAOX12q33Q06278 details
Xanthine dehydrogenase/oxidaseXDH2p23.1P47989 details
Thyroid peroxidaseTPO2p25P07202 details
LactoperoxidaseLPO17q23.1P22079 details
MyeloperoxidaseMPO17q23.1P05164 details
Eosinophil peroxidaseEPX17q23.1P11678 details
Amiloride-sensitive amine oxidase [copper-containing]ABP17q36.1P19801 details
Membrane primary amine oxidaseAOC317q21Q16853 details
Retina-specific copper amine oxidaseAOC217q21O75106 details
Protein-lysine 6-oxidaseLOX5q23.2P28300 details
Sulfite oxidase, mitochondrialSUOX12q13.2P51687 details
CatalaseCAT11p13P04040 details
Superoxide dismutase [Mn], mitochondrialSOD26q25.3P04179 details
Superoxide dismutase [Cu-Zn]SOD121q22.11P00441 details
Dual oxidase 2DUOX215q15.3Q9NRD8 details
Extracellular superoxide dismutase [Cu-Zn]SOD34p15.2P08294 details
Dual oxidase 1DUOX115q15.3Q9NRD9 details
Peroxidasin homologPXDN2p25Q92626 details
Peroxidasin-like proteinPXDNL8q11.22-q11.23A1KZ92 details
Lysyl oxidase homolog 2LOXL28p21.3Q9Y4K0 details
NADPH oxidase 4NOX411q14.2-q21Q9NPH5 details
Receptors
Protein NameGene NameLocusUniprot IDDetails
Amiloride-sensitive amine oxidase [copper-containing]ABP17q36.1P19801 details
Superoxide dismutase [Cu-Zn]SOD121q22.11P00441 details
Peroxidasin homologPXDN2p25Q92626 details
Lysyl oxidase homolog 2LOXL28p21.3Q9Y4K0 details
Transcriptional Factors
Protein NameGene NameLocusUniprot IDDetails
Glutathione peroxidase 3GPX35q23P22352 details
CatalaseCAT11p13P04040 details
Superoxide dismutase [Mn], mitochondrialSOD26q25.3P04179 details
Peroxiredoxin-5, mitochondrialPRDX511q13P30044 details
Lysyl oxidase homolog 2LOXL28p21.3Q9Y4K0 details
Concentrations Data
Not Available
HMDB IDHMDB0003125
DrugBank IDDB11091
Phenol Explorer Compound IDNot Available
FoodDB IDFDB014562
KNApSAcK IDNot Available
Chemspider ID763
KEGG Compound IDC00027
BioCyc IDHYDROGEN-PEROXIDE
BiGG ID33570
Wikipedia LinkHydrogen_peroxide
METLIN IDNot Available
PubChem Compound784
PDB IDNot Available
ChEBI ID16240
References
General ReferencesNot Available

Only showing the first 10 proteins. There are 80 proteins in total.

Enzymes

General function:
Involved in oxidoreductase activity
Specific function:
Metabolizes sarcosine, L-pipecolic acid and L-proline.
Gene Name:
PIPOX
Uniprot ID:
Q9P0Z9
Molecular weight:
44065.515
General function:
Amino acid transport and metabolism
Specific function:
Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
Gene Name:
PAOX
Uniprot ID:
Q6QHF9
Molecular weight:
55512.64
General function:
Involved in oxidoreductase activity
Specific function:
Not Available
Gene Name:
AOX1
Uniprot ID:
Q06278
Molecular weight:
147916.735
General function:
Involved in acyl-CoA dehydrogenase activity
Specific function:
Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy-palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl-CoA.
Gene Name:
ACOX1
Uniprot ID:
Q15067
Molecular weight:
70135.205
General function:
Involved in D-amino-acid oxidase activity
Specific function:
Selectively catalyzes the oxidative deamination of D-aspartate and its N-methylated derivative, N-methyl D-aspartate.
Gene Name:
DDO
Uniprot ID:
Q99489
Molecular weight:
40992.53
General function:
Involved in oxidoreductase activity
Specific function:
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.
Gene Name:
MAOB
Uniprot ID:
P27338
Molecular weight:
58762.475
General function:
Involved in oxidoreductase activity
Specific function:
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.
Gene Name:
MAOA
Uniprot ID:
P21397
Molecular weight:
59681.27
General function:
Involved in oxidoreductase activity
Specific function:
Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro).
Gene Name:
XDH
Uniprot ID:
P47989
Molecular weight:
146422.99
General function:
Involved in catalytic activity
Specific function:
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
Gene Name:
DHODH
Uniprot ID:
Q02127
Molecular weight:
42866.93
General function:
Involved in oxidoreductase activity, acting on the CH-CH group of donors
Specific function:
Oxidizes the CoA-esters of 2-methyl-branched fatty acids (By similarity).
Gene Name:
ACOX3
Uniprot ID:
O15254
Molecular weight:
69574.075

Only showing the first 10 proteins. There are 80 proteins in total.