Showing Protein Glutathione peroxidase 7 (CDBP00754)
| Identification | |||||||||||||||||
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| HMDB Protein ID | CDBP00754 | ||||||||||||||||
| Secondary Accession Numbers | Not Available | ||||||||||||||||
| Name | Glutathione peroxidase 7 | ||||||||||||||||
| Description | Not Available | ||||||||||||||||
| Synonyms |
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| Gene Name | GPX7 | ||||||||||||||||
| Protein Type | Enzyme | ||||||||||||||||
| Biological Properties | |||||||||||||||||
| General Function | Involved in glutathione peroxidase activity | ||||||||||||||||
| Specific Function | It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks. | ||||||||||||||||
| GO Classification |
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| Cellular Location |
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| Pathways | Not Available | ||||||||||||||||
| Gene Properties | |||||||||||||||||
| Chromosome Location | 1 | ||||||||||||||||
| Locus | 1p32 | ||||||||||||||||
| SNPs | GPX7 | ||||||||||||||||
| Gene Sequence |
>564 bp ATGGTGGCGGCGACGGTGGCAGCGGCGTGGCTGCTCCTGTGGGCTGCGGCCTGCGCGCAG CAGGAGCAGGACTTCTACGACTTCAAGGCGGTCAACATCCGGGGCAAACTGGTGTCGCTG GAGAAGTACCGCGGATCGGTGTCCCTGGTGGTGAATGTGGCCAGCGAGTGCGGCTTCACA GACCAGCACTACCGAGCCCTGCAGCAGCTGCAGCGAGACCTGGGCCCCCACCACTTTAAC GTGCTCGCCTTCCCCTGCAACCAGTTTGGCCAACAGGAGCCTGACAGCAACAAGGAGATT GAGAGCTTTGCCCGCCGCACCTACAGTGTCTCATTCCCCATGTTTAGCAAGATTGCAGTC ACCGGTACTGGTGCCCATCCTGCCTTCAAGTACCTGGCCCAGACTTCTGGGAAGGAGCCC ACCTGGAACTTCTGGAAGTACCTAGTAGCCCCAGATGGAAAGGTGGTAGGGGCTTGGGAC CCAACTGTGTCAGTGGAGGAGGTCAGACCCCAGATCACAGCGCTCGTGAGGAAGCTCATC CTACTGAAGCGAGAAGACTTATAA |
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| Protein Properties | |||||||||||||||||
| Number of Residues | 187 | ||||||||||||||||
| Molecular Weight | 20995.88 | ||||||||||||||||
| Theoretical pI | 8.268 | ||||||||||||||||
| Pfam Domain Function |
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| Signals | Not Available | ||||||||||||||||
| Transmembrane Regions | Not Available | ||||||||||||||||
| Protein Sequence |
>Glutathione peroxidase 7 MVAATVAAAWLLLWAAACAQQEQDFYDFKAVNIRGKLVSLEKYRGSVSLVVNVASECGFT DQHYRALQQLQRDLGPHHFNVLAFPCNQFGQQEPDSNKEIESFARRTYSVSFPMFSKIAV TGTGAHPAFKYLAQTSGKEPTWNFWKYLVAPDGKVVGAWDPTVSVEEVRPQITALVRKLI LLKREDL |
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| External Links | |||||||||||||||||
| GenBank ID Protein | Not Available | ||||||||||||||||
| UniProtKB/Swiss-Prot ID | Q96SL4 | ||||||||||||||||
| UniProtKB/Swiss-Prot Entry Name | GPX7_HUMAN | ||||||||||||||||
| PDB IDs | |||||||||||||||||
| GenBank Gene ID | AF320068 | ||||||||||||||||
| GeneCard ID | GPX7 | ||||||||||||||||
| GenAtlas ID | GPX7 | ||||||||||||||||
| HGNC ID | HGNC:4559 | ||||||||||||||||
| References | |||||||||||||||||
| General References | Not Available | ||||||||||||||||