Cannabis Compound Database: Showing Compound Card for Isopropyl alcohol (CDB000734)

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Identification Taxonomy Ontology Physical properties Spectra Protein target Pathways Concentrations Links References enzymes (42)transporters (1) Show 69 proteins XML

Record Information

Version

1.0

Created at

2020-03-19 00:53:49 UTC

Updated at

2020-12-07 19:07:44 UTC

CannabisDB ID

CDB000734

Secondary Accession Numbers

Not Available

Cannabis Compound Identification

Common Name

Isopropyl alcohol

Description

Isopropyl alcohol, also known as isopropanol, rubbing alcohol or IPA, belongs to the class of organic compounds known as secondary alcohols. Secondary alcohols are compounds containing a secondary alcohol functional group, with the general structure HOC(R)(R') (R, R'=alkyl, aryl). Isopropanol is the simplest example of a secondary alcohol, where the alcohol carbon is attached to two other carbons sometimes shown as (CH3)2CHOH. It is a structural isomer of 1-propanol. Isopropanol is a colorless, flammable liquid with a strong odor. It is miscible in water, ethanol, ether, and chloroform. Isoproanol is produced industrially via the hydrogenation of acetone or the hydration of propene with water. It is widely used as a solvent for coatings, as a cleaning fluid (for eyeglasses and electrical contacts) and as a solvent for household or personal care products such as antiseptics, disinfectants, and detergents. Isopropanol has an alcoholic, musty or woody aroma and a similar woody or musty taste. Isopropanol is an approved food additive and is used in cosmetics as an antifoaming agent, a perfuming agent and a viscosity controlling agent. It is frequently used as an extraction solvent in food preparation. Isopropanol is also naturally present in apple, cognac, roselle fruit and papaya (Carica papaya) and contributes to their distinct odor. Isopropanol and its metabolite, acetone, act as central nervous system (CNS) depressants (PMID: 24815348 ). It is oxidized to form acetone by alcohol dehydrogenase in the liver (PMID: 12726989 ). Unlike methanol or ethylene glycol poisoning, the metabolites of isopropanol are considerably less toxic, and treatment is largely supportive. Isopropanol is found in trace amounts from extracted plant essential oil. As a result, it can be found in hemp, CBD or cannabis oils.

Structure

MOL SDF PDB SMILES InChI

Synonyms

Value	Source
1-Methylethanol	ChEBI
1-Methylethyl alcohol	ChEBI
2-Hydroxypropane	ChEBI
2-Propanol	ChEBI
I-propanol	ChEBI
I-propylalkohol	ChEBI
IPA	ChEBI
Isopropanol	ChEBI
Isopropylalkohol	ChEBI
Sec-propanol	ChEBI
Isopro	Kegg
2-Propyl alcohol	HMDB
Alcojel	HMDB
Alkolave	HMDB
Avantin	HMDB
Avantine	HMDB
Hartosol	HMDB
Lavaco	HMDB
Petrohol	HMDB
Takineocol	HMDB
Alcohol, isopropyl	HMDB
Alcohol, rubbing	HMDB
Rubbing alcohol	HMDB
2 Propanol	HMDB
ISOPROPYL alcohol	ChEBI

Chemical Formula

C₃H₈O

Average Molecular Weight

60.1

Monoisotopic Molecular Weight

60.0575

IUPAC Name

propan-2-ol

Traditional Name

isopropyl alcohol

CAS Registry Number

67-63-0

SMILES

CC(C)O

InChI Identifier

InChI=1S/C3H8O/c1-3(2)4/h3-4H,1-2H3

InChI Key

KFZMGEQAYNKOFK-UHFFFAOYSA-N

Chemical Taxonomy

Description

Belongs to the class of organic compounds known as secondary alcohols. Secondary alcohols are compounds containing a secondary alcohol functional group, with the general structure HOC(R)(R') (R,R'=alkyl, aryl).

Kingdom

Organic compounds

Super Class

Organic oxygen compounds

Class

Organooxygen compounds

Sub Class

Alcohols and polyols

Direct Parent

Secondary alcohols

Alternative Parents

Hydrocarbon derivatives

Substituents

Secondary alcohol
Hydrocarbon derivative
Aliphatic acyclic compound

Molecular Framework

Aliphatic acyclic compounds

External Descriptors

secondary alcohol (CHEBI:17824 )
a small molecule (ISO-PROPANOL )

Ontology

Physiological effect

Health effect:

Health condition:

Isopropyl alcohol poisoning

Disposition

Route of exposure:

Enteral:

Ingestion

Source:

Synthetic:

Personal care product

Biological:

Plant

Microbe:

Clostridium:

Biological location:

Tissue and substructures:

Epidermis

Cell and elements:

Element:

Platelet

Organ and components:

Subcellular:

Biofluid and excreta:

Role

Environmental role:

Air pollutant

Industrial application:

Food and nutrition

Personal care products:

Perfuming agent

Household products:

Antimicrobial agent:

Disinfectant

Pharmaceutical industry:

Pharmaceutical

Physical Properties

State

Solid

Experimental Properties

Property	Value	Reference
Melting Point	Not Available	Not Available
Boiling Point	82.6 °C	Wikipedia
Water Solubility	1000 mg/mL	Not Available
logP	0.05	HANSCH,C ET AL. (1995)

Predicted Properties

Property	Value	Source
logP	0.04	ALOGPS
logP	0.25	ChemAxon
logS	0.8	ALOGPS
pKa (Strongest Acidic)	17.26	ChemAxon
pKa (Strongest Basic)	-1.8	ChemAxon
Physiological Charge	0	ChemAxon
Hydrogen Acceptor Count	1	ChemAxon
Hydrogen Donor Count	1	ChemAxon
Polar Surface Area	20.23 Å²	ChemAxon
Rotatable Bond Count	0	ChemAxon
Refractivity	17.43 m³·mol⁻¹	ChemAxon
Polarizability	7.14 Å³	ChemAxon
Number of Rings	0	ChemAxon
Bioavailability	Yes	ChemAxon
Rule of Five	Yes	ChemAxon
Ghose Filter	No	ChemAxon
Veber's Rule	Yes	ChemAxon
MDDR-like Rule	No	ChemAxon

Spectra

EI-MS/GC-MS

Type	Description	Splash Key	View
EI-MS	Mass Spectrum (Electron Ionization)	splash10-0002-9000000000-8f0393a68e54e5668638	2014-09-20	View Spectrum
GC-MS	Isopropyl alcohol, non-derivatized, GC-MS Spectrum	splash10-0002-9000000000-b56f808ef55c854e8324	Spectrum
GC-MS	Isopropyl alcohol, non-derivatized, GC-MS Spectrum	splash10-0002-9000000000-f68d78a99d0ee77081c8	Spectrum
GC-MS	Isopropyl alcohol, non-derivatized, GC-MS Spectrum	splash10-0002-9000000000-a1c27780d39325f67c84	Spectrum
GC-MS	Isopropyl alcohol, non-derivatized, GC-MS Spectrum	splash10-0002-9000000000-40a45591af6378500aeb	Spectrum
GC-MS	Isopropyl alcohol, non-derivatized, GC-MS Spectrum	splash10-0002-9000000000-2261ea7d03d835d46644	Spectrum
GC-MS	Isopropyl alcohol, non-derivatized, GC-MS Spectrum	splash10-0002-9000000000-3c81c56ab53eb5aaa2ec	Spectrum
GC-MS	Isopropyl alcohol, non-derivatized, GC-MS Spectrum	splash10-0002-9000000000-7936ed4d93d5699b0366	Spectrum
GC-MS	Isopropyl alcohol, non-derivatized, GC-MS Spectrum	splash10-0002-9000000000-b56f808ef55c854e8324	Spectrum
GC-MS	Isopropyl alcohol, non-derivatized, GC-MS Spectrum	splash10-0002-9000000000-f68d78a99d0ee77081c8	Spectrum
GC-MS	Isopropyl alcohol, non-derivatized, GC-MS Spectrum	splash10-0002-9000000000-a1c27780d39325f67c84	Spectrum
GC-MS	Isopropyl alcohol, non-derivatized, GC-MS Spectrum	splash10-0002-9000000000-40a45591af6378500aeb	Spectrum
GC-MS	Isopropyl alcohol, non-derivatized, GC-MS Spectrum	splash10-0002-9000000000-2261ea7d03d835d46644	Spectrum
GC-MS	Isopropyl alcohol, non-derivatized, GC-MS Spectrum	splash10-0002-9000000000-3c81c56ab53eb5aaa2ec	Spectrum
GC-MS	Isopropyl alcohol, non-derivatized, GC-MS Spectrum	splash10-0002-9000000000-7936ed4d93d5699b0366	Spectrum
Predicted GC-MS	Isopropyl alcohol, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	splash10-0006-9000000000-026d02184beec46b90cc	Spectrum
Predicted GC-MS	Isopropyl alcohol, 1 TMS, Predicted GC-MS Spectrum - 70eV, Positive	splash10-010c-9200000000-82e9183374d718888481	Spectrum
Predicted GC-MS	Isopropyl alcohol, non-derivatized, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum
Predicted GC-MS	Isopropyl alcohol, TBDMS_1_1, Predicted GC-MS Spectrum - 70eV, Positive	Not Available	Spectrum

MS/MS

Type	Description	Splash Key	View
MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 10V, Positive (Annotated)	splash10-03di-9000000000-958007b112253f530fa1	2012-07-24	View Spectrum
MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 25V, Positive (Annotated)	splash10-03dl-9000000000-eec0fd84c38e3cc2fb7d	2012-07-24	View Spectrum
MS/MS	LC-MS/MS Spectrum - Quattro_QQQ 40V, Positive (Annotated)	splash10-03di-9000000000-e524005ac3e29f5e6e60	2012-07-24	View Spectrum
MS/MS	LC-MS/MS Spectrum - EI-B (HITACHI RMU-6M) , Positive	splash10-0002-9000000000-b56f808ef55c854e8324	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - EI-B (JEOL JMS-D-3000) , Positive	splash10-0002-9000000000-2261ea7d03d835d46644	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - EI-B (HITACHI M-80B) , Positive	splash10-0002-9000000000-3c81c56ab53eb5aaa2ec	2012-08-31	View Spectrum
MS/MS	LC-MS/MS Spectrum - EI-B (HITACHI RMU-7M) , Positive	splash10-0002-9000000000-7936ed4d93d5699b0366	2012-08-31	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-03di-9000000000-52e1a906e58615d920fd	2015-04-24	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-03di-9000000000-e66cba449fc3e39cabcb	2015-04-24	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-0006-9000000000-34d2b3ce7e4949d6207e	2015-04-24	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-0a4i-9000000000-06d1878fb0f08269b040	2015-04-25	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-0a4i-9000000000-a3c0cec1f0523a5089d6	2015-04-25	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-0a4i-9000000000-b7cef7808f5c6bfd85c9	2015-04-25	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 10V, Negative	splash10-0a4i-9000000000-28b1a4f33a69b25b3b12	2021-09-25	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 20V, Negative	splash10-0a4i-9000000000-28b1a4f33a69b25b3b12	2021-09-25	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 40V, Negative	splash10-0a4i-9000000000-c6a8f10b148e0b66c2de	2021-09-25	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 10V, Positive	splash10-0006-9000000000-5381c9dfee7dd1735ffd	2021-09-25	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 20V, Positive	splash10-0006-9000000000-469388653449614be285	2021-09-25	View Spectrum
Predicted MS/MS	Predicted LC-MS/MS Spectrum - 40V, Positive	splash10-0006-9000000000-8d43c0c8144267964937	2021-09-25	View Spectrum

NMR

Type	Description	View
1D NMR	¹H NMR Spectrum (1D, 500 MHz, H₂O, experimental)	Spectrum
1D NMR	¹H NMR Spectrum (1D, 90 MHz, CDCl₃, experimental)	Spectrum
1D NMR	¹³C NMR Spectrum (1D, 15.09 MHz, CDCl₃, experimental)	Spectrum
2D NMR	[¹H, ¹³C]-HSQC NMR Spectrum (2D, 600 MHz, H₂O, experimental)	Spectrum

Pathways

Not Available

Protein Targets

Enzymes

Protein Name	Gene Name	Locus	Uniprot ID	Details
Phospholipase A2, membrane associated	PLA2G2A	1p35	P14555	details
Serum paraoxonase/lactonase 3	PON3	7q21.3	Q15166	details
Serum paraoxonase/arylesterase 1	PON1	7q21.3	P27169	details
Serum paraoxonase/arylesterase 2	PON2	7q21.3	Q15165	details
Intestinal-type alkaline phosphatase	ALPI	2q37.1	P09923	details
Lysosomal acid phosphatase	ACP2	11p12-p11	P11117	details
Alkaline phosphatase, tissue-nonspecific isozyme	ALPL	1p36.12	P05186	details
Tartrate-resistant acid phosphatase type 5	ACP5	19p13.2	P13686	details
Alkaline phosphatase, placental-like	ALPPL2	2q37	P10696	details
Peroxiredoxin-6	PRDX6	1q25.1	P30041	details
Aldehyde dehydrogenase X, mitochondrial	ALDH1B1	9p11.1	P30837	details
L-xylulose reductase	DCXR	17q25.3	Q7Z4W1	details
Sulfotransferase family cytosolic 2B member 1	SULT2B1	19q13.3	O00204	details
Ribonuclease pancreatic	RNASE1	14q11.2	P07998	details
Sorbitol dehydrogenase	SORD	15q15.3	Q00796	details
Alcohol dehydrogenase [NADP(+)]	AKR1A1	1p33-p32	P14550	details
Alcohol dehydrogenase 4	ADH4	4q22	P08319	details
Adenosylhomocysteinase	AHCY	20q11.22	P23526	details
Alcohol dehydrogenase 1B	ADH1B	4q23	P00325	details
Alcohol dehydrogenase 1A	ADH1A	4q23	P07327	details
Alcohol dehydrogenase 6	ADH6	4q23	P28332	details
Beta-glucuronidase	GUSB	7q21.11	P08236	details
Plasma alpha-L-fucosidase	FUCA2	6q24	Q9BTY2	details
GTP cyclohydrolase 1	GCH1	14q22.1-q22.2	P30793	details
Trans-2-enoyl-CoA reductase, mitochondrial	MECR	1p35.3	Q9BV79	details
Chitotriosidase-1	CHIT1		Q13231	details
Ganglioside GM2 activator	GM2A	5q33.1	P17900	details
Lecithin retinol acyltransferase	LRAT	4q32.1	O95237	details
Tumor necrosis factor	TNF	6p21.3	P01375	details
Nuclear receptor subfamily 1 group I member 3	NR1I3	1q23.3	Q14994	details
Zinc-binding alcohol dehydrogenase domain-containing protein 2	ZADH2	18q22.3	Q8N4Q0	details
Hydroxyacid-oxoacid transhydrogenase, mitochondrial	ADHFE1	8q13.1	Q8IWW8	details
Fatty acyl-CoA reductase 2	FAR2	12p11.22	Q96K12	details
Acyl-CoA wax alcohol acyltransferase 2	AWAT2	Xq13.1	Q6E213	details
Testicular acid phosphatase	ACPT	19q13.4	Q9BZG2	details
Carboxylesterase 5A	CES5A	16q12.2	Q6NT32	details
Spliceosome RNA helicase DDX39B	DDX39B	6p21.3	Q13838	details
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase	ADI1	2p25.3	Q9BV57	details
Acid phosphatase-like protein 2	ACPL2	3q23	Q8TE99	details
Synaptic vesicle membrane protein VAT-1 homolog-like	VAT1L	16q23.1	Q9HCJ6	details
Quinone oxidoreductase PIG3	TP53I3	2p23.3	Q53FA7	details
Synaptic vesicle membrane protein VAT-1 homolog	VAT1	17q21	Q99536	details

Transporters

Protein Name	Gene Name	Locus	Uniprot ID	Details
Serum paraoxonase/arylesterase 1	PON1	7q21.3	P27169	details

Metal Bindings

Protein Name	Gene Name	Locus	Uniprot ID	Details
Phospholipase A2, membrane associated	PLA2G2A	1p35	P14555	details
Serum paraoxonase/lactonase 3	PON3	7q21.3	Q15166	details
Serum paraoxonase/arylesterase 2	PON2	7q21.3	Q15165	details
Intestinal-type alkaline phosphatase	ALPI	2q37.1	P09923	details
Alkaline phosphatase, tissue-nonspecific isozyme	ALPL	1p36.12	P05186	details
Alkaline phosphatase, placental-like	ALPPL2	2q37	P10696	details
Sorbitol dehydrogenase	SORD	15q15.3	Q00796	details
Alcohol dehydrogenase 4	ADH4	4q22	P08319	details
Alcohol dehydrogenase 1B	ADH1B	4q23	P00325	details
Alcohol dehydrogenase 1A	ADH1A	4q23	P07327	details
Alcohol dehydrogenase 6	ADH6	4q23	P28332	details
Trans-2-enoyl-CoA reductase, mitochondrial	MECR	1p35.3	Q9BV79	details
Nuclear receptor subfamily 1 group I member 3	NR1I3	1q23.3	Q14994	details
Zinc-binding alcohol dehydrogenase domain-containing protein 2	ZADH2	18q22.3	Q8N4Q0	details
Hydroxyacid-oxoacid transhydrogenase, mitochondrial	ADHFE1	8q13.1	Q8IWW8	details
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase	ADI1	2p25.3	Q9BV57	details
Synaptic vesicle membrane protein VAT-1 homolog-like	VAT1L	16q23.1	Q9HCJ6	details
Quinone oxidoreductase PIG3	TP53I3	2p23.3	Q53FA7	details
Synaptic vesicle membrane protein VAT-1 homolog	VAT1	17q21	Q99536	details
Reticulon-4-interacting protein 1, mitochondrial	RTN4IP1	6q21	Q8WWV3	details

Receptors

Protein Name	Gene Name	Locus	Uniprot ID	Details
Tumor necrosis factor	TNF	6p21.3	P01375	details
Nuclear receptor subfamily 1 group I member 3	NR1I3	1q23.3	Q14994	details
Klotho	KL	13q12	Q9UEF7	details

Transcriptional Factors

Protein Name	Gene Name	Locus	Uniprot ID	Details
mRNA-capping enzyme	RNGTT	6q16	O60942	details
Nuclear receptor subfamily 1 group I member 3	NR1I3	1q23.3	Q14994	details
Spliceosome RNA helicase DDX39B	DDX39B	6p21.3	Q13838	details

Concentrations Data

Not Available

External Links

HMDB ID

HMDB0000863

DrugBank ID

DB02325

Phenol Explorer Compound ID

Not Available

FoodDB ID

KNApSAcK ID

Chemspider ID

KEGG Compound ID

BioCyc ID

BiGG ID

Not Available

Wikipedia Link

Isopropyl_Alcohol

METLIN ID

4192

PubChem Compound

3776

PDB ID

Not Available

ChEBI ID

17824

References

General References

Slaughter RJ, Mason RW, Beasley DM, Vale JA, Schep LJ: Isopropanol poisoning. Clin Toxicol (Phila). 2014 Jun;52(5):470-8. doi: 10.3109/15563650.2014.914527. Epub 2014 May 9. [PubMed:24815348 ]
Kalapos MP: On the mammalian acetone metabolism: from chemistry to clinical implications. Biochim Biophys Acta. 2003 May 2;1621(2):122-39. doi: 10.1016/s0304-4165(03)00051-5. [PubMed:12726989 ]

Only showing the first 10 proteins. There are 69 proteins in total.

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Enzymes

Enzyme Details

1. Phospholipase A2, membrane associated

General function:: Involved in phospholipase A2 activity
Specific function:: Thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
Gene Name:: PLA2G2A
Uniprot ID:: P14555
Molecular weight:: 16082.525

Enzyme Details

2. Serum paraoxonase/lactonase 3

General function:: Involved in arylesterase activity
Specific function:: Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.g. lovastatin). Hydrolyzes aromatic lactones and 5- or 6-member ring lactones with aliphatic substituents but not simple lactones or those with polar substituents.
Gene Name:: PON3
Uniprot ID:: Q15166
Molecular weight:: 39607.185

Enzyme Details

3. Serum paraoxonase/arylesterase 1

General function:: Involved in arylesterase activity
Specific function:: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
Gene Name:: PON1
Uniprot ID:: P27169
Molecular weight:: 39730.99

Enzyme Details

4. Serum paraoxonase/arylesterase 2

General function:: Involved in arylesterase activity
Specific function:: Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis.
Gene Name:: PON2
Uniprot ID:: Q15165
Molecular weight:: 39380.535

Enzyme Details

5. Intestinal-type alkaline phosphatase

General function:: Involved in catalytic activity
Specific function:: Not Available
Gene Name:: ALPI
Uniprot ID:: P09923
Molecular weight:: 56811.695

Enzyme Details

6. Lysosomal acid phosphatase

General function:: Involved in acid phosphatase activity
Specific function:: Not Available
Gene Name:: ACP2
Uniprot ID:: P11117
Molecular weight:: 48343.92

Enzyme Details

7. Alkaline phosphatase, tissue-nonspecific isozyme

General function:: Involved in catalytic activity
Specific function:: This isozyme may play a role in skeletal mineralization.
Gene Name:: ALPL
Uniprot ID:: P05186
Molecular weight:: 57304.435

Enzyme Details

8. Tartrate-resistant acid phosphatase type 5

General function:: Involved in hydrolase activity
Specific function:: Involved in osteopontin/bone sialoprotein dephosphorylation. Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias.
Gene Name:: ACP5
Uniprot ID:: P13686
Molecular weight:: 36598.47

Enzyme Details

9. Alkaline phosphatase, placental-like

General function:: Involved in catalytic activity
Specific function:: Not Available
Gene Name:: ALPPL2
Uniprot ID:: P10696
Molecular weight:: 57376.515

Enzyme Details

10. Peroxiredoxin-6

General function:: Involved in antioxidant activity
Specific function:: Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
Gene Name:: PRDX6
Uniprot ID:: P30041
Molecular weight:: 25034.715

Transporters

Enzyme Details

1. Serum paraoxonase/arylesterase 1

General function:: Involved in arylesterase activity
Specific function:: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation.
Gene Name:: PON1
Uniprot ID:: P27169
Molecular weight:: 39730.99

Only showing the first 10 proteins. There are 69 proteins in total.

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Showing Compound Card for Isopropyl alcohol (CDB000734)

Structure for CDB000734 (Isopropyl alcohol)

Enzymes

Transporters